AML, Acute myeloid leukemia; BL, Burkitt’s lymphoma; CLL, chronic lymphocytic leukemia; DLBCL, diffuse large B-cell lymphoma; ES, Ewing sarcoma.
Main Types of Therapeutic RNA Molecules
Table 55-2
Glossary of Terms in RNA-Inhibition Strategies
Ribozymes
siRNAs and shRNAs

ASOs/AMOs Anti-miRNAs, LNAS Anti-miRNAs, and Antagomirs
miRNA-Mimic Agents
In Search of the Right Way and the Right Type of Delivery
A Strategy for Using RNA as Therapeutic Molecules

Table 55-3
Delivery Methods for RNA-Interference–Based Therapeutics
dsDNA, Double-strand DNA; SNALP, stable nucleic acid-lipid particle; ssDNA, single-strand DNA.
Modified with permission from Kim DH, Rossi JJ. Strategies for silencing human disease using RNA interference. Nat Rev Genet. 2007;8:173-184.
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