Neurology and the Neuromuscular System

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Chapter 21 Neurology and the Neuromuscular System

Acetaminophen

MOA (Mechanism of Action) (Figure 21-1)

Important Notes

Overdose

Evidence

Analgesia

Opioids

Delta (δ)

Pharmacokinetics (Table 21-2)

image Important metabolites:

Side Effects

Important Notes

Evidence

α2 Agonists

Inhaled Anesthetics

Pharmacokinetics

image Inhaled anesthetics move through the body by dissolving in the blood and distributing into tissues; the important tissue interfaces include the following:

Important Notes

Intravenous Anesthetics

Important Notes

Local Anesthetics

MOA (Mechanism of Action)

Pharmacokinetics

TABLE 21-3 Local Anesthetic Durations

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Agent Duration Plain (minutes) Duration with Epinephrine (minutes)
2-Chloroprocaine 20-30 30-45
Procaine 15-30 30
Lidocaine 30-60 120
Mepivacaine 45-90 120
Prilocaine 30-90 120
Bupivacaine 120-240 180-240
Ropivacaine