Chapter 295 Cysticercosis
Etiology
Humans can be the definitive host (parasite sexual reproduction) as well as the intermediate host (parasite asexual reproduction) of Taenia solium, the pork tapeworm. Infection with the invasive intermediate stage (cysticercus) is called cysticercosis. Unlike Taenia saginata, the intermediate stage of T. solium is invasive with a tropism for the central nervous system (CNS) in humans, causing neurocysticercosis. The risk of cysticercosis may be the same for individuals who eat or do not eat pork, since humans acquire the intermediate form by ingestion of food or water contaminated with the eggs of T. solium. By contrast, consumption of infected undercooked pork produces intestinal infection with the adult worm (Chapter 294). Individuals harboring an adult worm may infect themselves with the eggs by the fecal-oral route. Reverse peristalsis in the small intestine has also been implicated as a means of autoinfection. In the small intestine, the egg releases an oncosphere that crosses the gut wall and spreads hematogenously to many tissues, primarily brain and muscle. Wherever the eggs lodge, they produce small (0.2-0.5 cm) fluid-filled bladders containing a single protoscolex, the juvenile-stage parasite.