Cysticercosis

Published on 25/03/2015 by admin

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Last modified 25/03/2015

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Chapter 295 Cysticercosis

Clinical Manifestations

Seizures are the presenting finding in ~70% of cases, although any cognitive or neurologic abnormality ranging from psychosis to stroke may be a manifestation of cysticercosis. It is useful to classify neurocysticercosis as parenchymal, intraventricular, meningeal, spinal, or ocular on the basis of anatomic location, clinical presentation, and radiologic appearance. Prognosis and management vary with location.

Parenchymal neurocysticercosis produces seizures as well as focal neurologic deficits. The seizures are generalized in 80% of cases but frequently begin as simple or complex partial seizures. Rarely, cerebral infarction can result from obstruction of small terminal arteries or vasculitis. With extensive frontal lobe disease, symptoms of intellectual deterioration with dementia or parkinsonism may obfuscate diagnosis until focal signs appear. A fulminant encephalitis-like presentation also occurs, most frequently in children who have had a massive initial infection. Intraventricular neurocysticercosis (5-10% of all cases) is associated with hydrocephalus and acute, subacute, or intermittent signs of increased intracranial pressure without localizing signs. The 4th ventricle is the most common site for obstruction and symptoms; cysts in the lateral ventricles are less likely to cause obstruction. Meningeal neurocysticercosis is associated with signs of meningeal irritation and also increased intracranial pressure that results from edema, inflammation, or the presence of a cyst obstructing flow of CSF. Chronic basilar meningitis is associated with many forms of neurocysticercosis, but predominantly meningeal presentations. Racemose neurocysticercosis is a meningeal form of disease in which large, lobulated cysts appear in the basal cisterns. Spinal neurocysticercosis