Transfusion Therapy for Coagulation Factor Deficiencies

Published on 04/03/2015 by admin

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Last modified 04/03/2015

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Chapter 52 Transfusion Therapy for Coagulation Factor Deficiencies

Elizabeth Roman, Peter J. Larson, Catherine S. Manno

Table 52-1 Dosing Regimens for Bleeding and Prophylaxis in Hemophilia

qod, Every other day.

* Depending on severity.

† Painless spontaneous hematuria often requires no treatment other than fluid intake. Persistence requires treatment and evaluation.

‡ Use of a schedule of 25 U/kg qod and a dose of 40 U/kg with an interval of 2 days between the next dose may increase compliance by decreasing infusions to three per week.

Data from DiMichele D: Hemophilia 1996. New approach to an old disease. Pediatr Clin North Am 43:709, 1996; Mannucci PM: Haemophilia treatment protocols around the world: Towards a consensus. Haemophilia 4:421, 1998; and Lusher J: Treatment of congenital coagulopathies, 1999, AABB Press.