Soft tissues
9.1
Gynaecomastia
Pharmacological
1. Oestrogens or drugs with oestrogen-like activity – treatment of carcinoma of the prostate; digitalis.
2. Enhanced oestrogen synthesis – gonadotrophins, phenytoin.
3. Anti-androgens – spironolactone, metronidazole, alkylating agents, ketoconazole.
4. Idiopathic – phenothiazines, tricyclic antidepressants, ACE inhibitors, omeprazole.