Lumbar sympathetic blockade

Published on 07/02/2015 by admin

Filed under Anesthesiology

Last modified 22/04/2025

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Lumbar sympathetic blockade

David M. Rosenfeld, MD

Lumbar sympathetic blockade was first fully described by Mandl in 1926. Currently, the modality is widely used as a diagnostic and therapeutic procedure in the treatment of a wide variety of medical conditions.

Relevant anatomy

The lumbar sympathetic ganglia are known to control the sympathetic impulses to the lower extremities. These structures may represent either a single fused elongated mass or up to six separate ganglia spanning the L1 to L5 vertebra. As the sympathetic trunk passes into the abdomen, it begins a migration from a position that is more anterior to the vertebral bodies to a true anterolateral position by the midlumbar levels. On the right side, the sympathetic trunk is positioned posterior to the inferior vena cava, and, on the left, it is lateral and slightly posterior to the aorta. Injection techniques that position needles from L2 through L4 have been described. When approaching the ganglia, the best starting point is the area just cephalad to the middle of the body of the L3 vertebral body. This level has the highest probability of encountering the ganglia, variation is less, as compared with at L2 or L4, and the psoas muscle may terminate at the lower part of the L3 vertebra. The psoas muscle is well positioned posterior to the sympathetic chain, thus separating it from the somatic lumbar plexus and leading to fewer complications after injection, compared with other levels of the sympathetic chain.

Indications

The indications for lumbar sympathetic blockade fall into three main categories and serve both diagnostic and therapeutic purposes. First are conditions that result in circulatory insufficiency of the lower extremity, including atherosclerotic disease, arterial embolism, thromboangiitis, Raynaud phenomenon, frostbite, and following reconstructive vascular operations. Many of these conditions, such as claudication, rest pain, ischemic ulcers, and gangrene, are painful. The institution of continuous sympathetic blockade can transiently improve regional blood flow and predict the success of surgical sympathectomy or neurolytic therapy.

The second category involves pain from nonvascular causes and includes phantom or stump pain after amputation, varicella zoster or postherpetic neuralgia, renal colic, interstitial cystitis, complex regional pain syndrome, and labor analgesia. For complex regional pain syndrome, blocks are often performed in succession or continuously via a catheter and can improve analgesia and function in conjunction with pharmacologic and physical therapy. Lumbar sympathetic blockade is known to provide relief from the pain associated with the first stage of labor. Lack of effectiveness of lumbar sympathetic blockade for pain relief during the second stage of labor, concerns over potential intrathecal injection, technical difficulty, and the relative efficiency and ease of epidural analgesia have rendered lumbar sympathetic blockade rare in labor and delivery.

A third miscellaneous category includes nonpainful conditions such as lower extremity hyperhidrosis. The block is primarily used for diagnostic and predictive purposes prior to neurolysis or surgical sympathectomy. It has also been attempted on a limited basis to transiently improve renal function in patients with hepatorenal syndrome.

Technique

Patients are generally positioned prone, with pillow support provided beneath the lower abdomen to decrease lumbar lordosis and improve exposure of the L2 through L4 vertebrae. Establishment of intravenous access is recommended. Local infiltration of an anesthetic agent is mandatory along the needle track, and some clinicians use varying levels of conscious sedation in patients for whom specific diagnostic interaction is not necessary. The procedure routinely can be accomplished in 30 min and should be performed by clinicians who are experienced in performing percutaneous procedures and have knowledge of the relevant anatomy. Historically, the procedure was performed without radiographic assistance; however, currently, many clinicians use fluoroscopic guidance with anteroposterior, oblique, and lateral views to improve safety and precision. A myelographic iodinated contrast agent should be used if possible to help avoid intravascular injection and to enhance needle position and injection spread within the distribution of the ganglion. Currently, ultrasound-guided needle placement is being investigated, and some clinicians even employ computed tomography to guide needle placement. Transcutaneous temperature monitoring should be utilized to verify blockade; increases between 1°C and 8°C can be seen.

Brown single-needle technique

With this technique, the patient is placed in the prone position, and pillow support is provided. The needle is inserted 12.5 cm lateral to the spine at the level of the L4 vertebra, 1 cm cephalad to the ileum. A 22-gauge 14-cm needle is inserted at an angle of 35 to 40 degrees to the skin. The needle is directed medially until bone is contacted, and the needle lies at the anterolateral surface of the vertebra. The patient is then placed in a 5- to 140-degree Trendelenburg position, and 20 mL of local anesthetic agent is injected; the anesthetic agent should spread as high as L2. This oblique approach with insertion of the needle at the level of L4, versus a more cephalad position, is mandatory to avoid kidney injury. The Brown single-needle technique is infrequently used.

Lateral approach first described by reid

With this technique, the patient is again placed in the prone position with pillow support of the lower abdomen. Fluoroscopy is used for assistance in properly placing the needle. The spinous processes of L2, L3, and L4 are marked, and a site that is 7 to 8 cm lateral to midline at approximately the L2 to L3 transition is located. A spot that is perpendicular to the caudal aspect of the L2 vertebra, which corresponds to the interspace between the transverse process of L2 and L3, is marked. Reid described 7 cm as the optimal position to gain the proper trajectory to the ganglion of the vertebral body and to avoid injury to the renal parenchyma. This technique can be employed with a single needle at L3 or with as many as three needles positioned at L2, L3, and L4.

A 22-gauge 12-cm to 18-cm needle is advanced until it contacts the vertebral body at the cephalad portion of L3. The typical angle of insertion is 45 degrees, but this angle may be modified depending upon the patient’s body habitus. If bone is encountered soon after inserting the needle, the clinician has likely come into contact with a transverse process, and the needle trajectory should be modified cephalad or caudad to avoid contact with bone. If this occurs, the needle depth is noted, and the needle is retracted to skin level and redirected at a steeper angle under fluoroscopy to clear the lateral margin of the vertebra and position the tip at the anterolateral border of the vertebral body (Figure 219-1). The needle should be anterior to the psoas fascia. The needle is aspirated to verify extravascular position, taking into account the proximity of the aorta and vena cava. A small volume of iodinated contrast agent is injected, and spread should ideally be seen from L2 to L4. If spread is limited, additional needles can be placed at L2 and L4. Obtaining anteroposterior and lateral radiographic views helps to assess contrast spread, and, if striations (psoas stripe) are seen on fluoroscopy, the needle position may be too posterior.

It is helpful to initially inject 10 to 15 mL of lidocaine to document distal temperature rise and then follow with an additional 10 to 15 mL of bupivacaine. If temperature rise is not seen with initial injection, the needle should be repositioned and the local anesthetic agent reinjected, taking care to not exceed the maximum recommended dose of local anesthetic agent. The patient should be carefully monitored for the presence of lower extremity weakness and toxicity from the local anesthetic agent.

Mandl technique

With the Mandl technique, the spinous processes of L2 to L4 are marked, and a skin wheal is placed approximately 10 cm off midline with a local anesthetic agent injected at the L2 level and infiltrated to the transverse process. A 20-gauge, 12-cm needle is inserted to the level of the transverse process and then redirected medially toward the vertebral body 45 degrees to the coronal plane between the transverse processes. The needle is advanced, with the bevel toward the vertebral body, until contact is made; the needle is then adjusted to a position that allows it to slide 1 cm off the vertebral body. The position can be verified by loss of resistance and negative aspiration for cerebrospinal fluid, blood, or urine. Movement of the needle with normal respiration indicates lateral positioning in the diaphragmatic crus. Radiographic screening with contrast injection is recommended to ensure proper needle positioning, especially for neurolytic blocks. Alternatively, ultrasonography may be used, sparing the patient and physician radiation exposure. The procedure is repeated at the L4 level. Catheters may be placed if an 18-gauge needle is used.