Published on 27/03/2015 by admin
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Chapter 517 Introduction to the Child with Proteinuria
Priya Pais, Ellis D. Avner
The demonstration of proteinuria on a routine screening urinalysis is common; 10% of children aged 8-15 yr test positive for proteinuria by urinary dipstick at some time. The challenge is to differentiate the child with proteinuria related to renal disease from the otherwise healthy child with transient or other benign forms of proteinuria.
The urinary dipstick test offers a qualitative assessment of urinary protein excretion. Dipsticks primarily detect albuminuria and are less sensitive for other forms of proteinuria (low molecular weight proteins, Bence Jones protein, gamma globulins). Visual changes in the color of the dipstick are a semiquantitative measure of increasing urinary protein concentration. The dipstick is reported as negative, trace (10-20 mg/dL), 1+ (30 mg/dL), 2+ (100 mg/dL), 3+ (300 mg/dL), and 4+ (1000-2000 mg/dL).
Nelson Textbook of Pediatrics Expert Consult
