Hematologic Changes in Pregnancy

Published on 04/03/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 04/03/2015

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Chapter 67 Hematologic Changes in Pregnancy

Caroline Cromwell

Table 67-1 Initiation of Treatment in Pregnant Patients With Idiopathic Thrombocytopenic Purpura

Platelet Count Treatment
<10,000/µL Platelet transfusion for life-threatening bleeding
10,000-30,000/µL Consider monitoring in first trimester; treat in second or third trimester
>30,000/µL Clinically monitor
image

Figure 67-1 MICROANGIOPATHIC HEMOLYTIC ANEMIA.

Microangiopathic hemolytic anemia in pregnancy, peripheral blood smear (A and B). Evidence of microangiopathy with the formation of schistocytes, fragmented forms and spherocytes, associated with polychromasia and nucleated red blood cells (A and B, detail).

Imatinib Therapy

A 38-year-old woman with a history of chronic phase CML on imatinib therapy for 5 years becomes pregnant. She has had a complete cytogenetic response. She asks what to do about her imatinib therapy.

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