Chapter 67 Hematologic Changes in Pregnancy
Table 67-1 Initiation of Treatment in Pregnant Patients With Idiopathic Thrombocytopenic Purpura
Platelet Count | Treatment |
---|---|
<10,000/µL | Platelet transfusion for life-threatening bleeding |
10,000-30,000/µL | Consider monitoring in first trimester; treat in second or third trimester |
>30,000/µL | Clinically monitor |
Imatinib Therapy
Factor XIII | ↑/↓ |
Protein C, antithrombin | = |
Protein S | ↓ |
Factor XI | ↓/ = |
Factors V, VII, VIII, IX, X, XII | ↑ |
von Willebrand factor, fibrinogen | ↑ |
Tissue plasminogen activator | ↓ |
Prothrombin, D-dimer | ↑ |