Trauma Ultrasound

The trauma US examination is also called the focused assessment with sonography for trauma (FAST) examination.1,22,42 The trauma examination originally focused on the peritoneal space, as an evaluation for hemoperitoneum, with use of the right flank, left flank, and pelvic windows for detection of dependent peritoneal fluid and pleural effusion.⁴³ Newer versions include the EFAST (extended FAST) for the evaluation of potential pneumothorax and FASTER for evaluation of the extremities.^40,44–46

The FAST examination is based on the premise that a treating physician can sample known sonographic windows within minutes to evaluate the peritoneal, pericardial, and pleural spaces for fluid and abnormal fluid and air. Within the peritoneum, fluid circulates throughout the abdomen and pelvis and settles in dependent spaces.47,48 The volume of fluid required for a positive US study depends on the site of injury and site of sonographic detection, but 250 mL or more is generally visible, and nearly 600 mL of fluid is necessary to cause a positive flank stripe when fluid is infused from the pelvis.⁴⁹

Pericardial fluid is contained within the parietal and visceral pericardium. Once a certain volume is reached, the pressure in the pericardial space increases exponentially, causing pericardial tamponade.⁵⁰ In general, 50 mL is required to cause hemodynamic compromise in a patient without prior pericardial inflammation. However, tears in the pericardium that communicate with the pleural space or even the peritoneum can cause false-negative examination findings.

Pleural fluid can be detected by US, but this depends on the position of the body.⁵¹ Pneumothorax detection is based on the absence of the normal sonographic sliding of the visceral and parietal pleurae, although there are other signs (see thoracic section).

The torso trauma US examination (often called the EFAST) can detect pathologic free intraperitoneal fluid (typically hemoperitoneum, uroperitoneum, bile, or ascites), hemopericardium, hemothorax, or pneumothorax.45,46 Typically, fluid in the peritoneum, pericardium, and pleural cavity is anechoic, but it can have echogenicity with clotting, depending on the age of the clot or bowel contents. Compared with other fluid-filled structures in the abdomen and pelvis, peritoneal free fluid generally has sharp edges and an irregular shape, whereas most visceral or vascular structures have intrinsically smooth oval contours and less abrupt edge detail.

The FAST technique uses a low- to middle-frequency probe (2-5 MHz) to evaluate dependent peritoneal spaces, pleural spaces, and the pericardium. Within the peritoneum, dependent spaces include the following, grouped by tissue window: the right flank, which evaluates the hepatorenal space (also called Morison’s pouch; Fig. 196-1), the right subphrenic space, and the right costophrenic angle; the left flank, which evaluates the perisplenic space between the diaphragm and spleen, the splenorenal space, the perirenal space, and the left subphrenic space; and the suprapubic view, which is performed by placement of the transducer superior to the pubic bone with a full bladder to visualize the pouch of Douglas in women and the retrovesical space in men. Extra views include the paracolic gutters inferior from the flank views and medial from the iliac spine to visualize free fluid surrounding the bowel.⁵²

The typical cardiac views include the transverse subcostal images, which visualize the four cardiac chambers and pericardial space, and the sagittal subcostal view to assess the pericardial space and the collapsibility and diameter of the inferior vena cava (IVC), indicating right-sided heart pressures. A good alternative in patients with long chest walls or obesity is the parasternal view, which assesses the anterior and posterior pericardial spaces.

For pleural fluid, the superiorly angled flank views allow visualization of the costophrenic angles. The evaluation for pneumothorax uses either a low-frequency probe at a shallow depth or, more typically, a high-frequency probe for better resolution, placed at the anterior chest in the second intercostal space for anterior pneumothorax and at the axilla for large pneumothoraces and pleural effusion. Diaphragm injuries have been described with dislocation of typical organ patterns.⁵³

The sensitivity of the FAST examination ranges from 60 to 99%, and its specificity ranges from 80 to 99%.54–57 The large range of sensitivity is related to the comparative “gold standard” used for each study, with clinical endpoints suggesting higher accuracy. The FAST does not capture every peritoneal injury, although the need for intervention in undetected injuries has not been studied.⁵⁸ Randomized, controlled trials show lower morbidity, time to operating room, and charges for patients with US use during resuscitation, and a positive US study increases the odds ratio for laparotomy.^59,60

Patients with traumatic pericardial effusions are taken to the operating room sooner and have lower mortality rates with US.⁴⁴ However, the mediastinal injuries more common in blunt trauma have not been assessed without transesophageal echocardiography.^50,61 US can diagnose pneumothorax with excellent sensitivity and specificity compared with plain chest radiography and variable accuracy compared with computed tomography scanning.^62,63

There are certain populations of patients in whom FAST evaluation has limited benefit. With penetrating chest injuries, the FAST examination seems to be efficacious for both pericardial and nearby peritoneal injuries; but in patients with purely anterior penetrating trauma to the abdomen, the sensitivity of trauma US is poor because bowel injuries can occur without significant hemoperitoneum.58,59,64–66

The accuracy of the FAST examination may be lower in children than in adults, and many pediatric injuries can be observed or treated nonoperatively with angiography.⁶⁷ In obstetric patients, the few observational studies that have been performed have shown reasonable sensitivity and specificity, although abruption and fetal viability may necessitate an earlier operative course.⁶⁸

With pelvic fractures, the sensitivity ranges from 20 to 80%.69–72 More important, the detection of free fluid in an unstable patient with a pelvic fracture may be due to uroperitoneum from bladder injury rather than hemoperitoneum from vascular injury, clouding the decision for laparotomy versus pelvic embolization.⁶⁴ In addition, retroperitoneal injuries to the genitourinary tract are not assessed with four-quadrant FAST examination.

Pelvic Ultrasound

Pelvic US by emergency physicians was initiated to address one of the epidemics of the modern era—ectopic pregnancy.73–77 Typically, pelvic US is used to confirm intrauterine pregnancy, which indirectly excludes ectopic pregnancy in most patients.^78,79 A recent meta-analysis revealed a pooled sensitivity of 99.3% to rule out ectopic pregnancy when an intrauterine pregnancy was detected. Another use during pregnancy is the detection of fetal viability, incomplete abortion, ectopic pregnancy, and molar pregnancy. Pelvic US is used in nonpregnancy states to detect tubo-ovarian abscesses, masses, and hemoperitoneum in the hemodynamically unstable patient.⁸⁰

Indications for sonographic evaluation of the first-trimester pregnant patient include symptoms or signs that suggest an ectopic pregnancy, molar pregnancy, or fetal demise and dating of the pregnancy. Intrauterine pregnancy is confirmed with a gestational sac with a yolk sac or fetal pole within the fundus of the uterus (Fig. 196-2).⁷⁸ An embryonic or fetal demise has US findings of a fetal pole measuring more than 5 mm without fetal heart rate or a gestational sac of more than 20 mm in diameter without a fetal pole. A molar pregnancy appears as an echogenic, cystic uterus with disorganized echoes and is associated with high β-human chorionic gonadotropin concentrations without the sonographic finding of intrauterine pregnancy. Findings of an ectopic pregnancy include a chorionic ring or gestational sac with evidence of a yolk sac or fetal pole outside the uterus or in an abnormal location in the uterus, such as the cornu or cervix.⁷³ Excluding the groups of intrauterine pregnancy, embryonic demise, molar pregnancy, and ectopic pregnancy, there is a class called indeterminate, which may account for 20% of pregnant patients presenting to the ED in the first and early second trimesters. Heterotopic pregnancies can occur at a rate of 1/5000 and be detected by the same techniques and definitions.⁸¹

Pelvic US is performed by transabdominal or endovaginal techniques. The transabdominal technique uses a low-frequency transabdominal transducer placed over the lower abdomen suprapubically. Ideally, the patient has a full bladder, which provides a sonographic window, but this may not be necessary if the uterus is large or the patient is thin. Advantages of the transabdominal technique include wider field of view, detection of large pelvic masses, and greater depth of field. In the endovaginal technique, the transducer is placed in the vagina, optimally with an empty bladder to visualize the same structures. Endovaginal transducers are high frequency, providing excellent axial resolution but poor penetration of distant structures. Early intrauterine yolk sacs and fetal poles within gestational sacs may be detected more clearly, and ectopic pregnancies can be identified with more accuracy. Endovaginal US can detect small (7 mL) amounts of peritoneal fluid. Endovaginal US in the hemodynamically compromised patient has replaced culdocentesis for detection of ruptured ectopic pregnancy.

Emergency physician–performed pelvic US has reduced the morbidity of ectopic pregnancy by shortening the time to diagnosis and operating room treatment and has resulted in greater initial detection of abnormal pregnancy, reduced ED patient throughput times, and increased patient satisfaction with care.74,76,82–85 The detection of live intrauterine pregnancy predicts a rate of 91% continuation past 20 weeks, except for those with vaginal bleeding, who drop to a rate of 86%.⁸⁶ Further continuation of the pregnancy to term occurs in 77% of patients.⁸⁷ Emergency physicians can date pregnancies accurately by pelvic US with typical fetal biometry.⁸⁸

Emergency physicians are adept at identification of ectopic pregnancies by both transabdominal and endovaginal techniques.85,89–93 In addition, molar pregnancies and some malformation, such as conjoint twins, have been described.^94,95 The gynecologic differential diagnosis of significant free fluid in a pregnant woman, in addition to ectopic pregnancy, should include uterine rupture and ruptured corpus luteum pregnancy.⁹⁶ Pelvic US in nonpregnancy states has shown good accuracy for tubo-ovarian abscess and improved decision-making for female patients with right lower abdominal pain.^97,98

Cardiac Ultrasound

The use of cardiac US by emergency physicians is presentation and symptom specific and focused in nature. Indications include cardiac arrest, possible pericardial effusion, trauma, chest pain, hypotension, and procedural guidance.1,3,23,99 Cardiac US is often included in algorithms and protocols for certain symptoms or signs, such as dyspnea or hypotension.

Cardiac US is performed through the transthoracic and transabdominal windows with use of small curvilinear or phased array transducers. Typical views include the subcostal four-chamber and long-axis views, parasternal long-axis view, parasternal short-axis view, and apical four-chamber view. Although most emergency physicians are comfortable with the subcostal view from the FAST examination, the parasternal long-axis view is a good alternative and good window for left ventricular assessment.100,101 In addition, the apical four-chamber view provides excellent comparison of the right and left ventricles in terms of size and function. The long-axis subcostal view shows some of the right side of the heart but highlights the IVC, including size and respiratory variation.

Cardiac US performed by emergency physicians shows good accuracy in detection of pericardial effusion (Fig. 196-3), assessment of left ventricular function, and evaluation of patients with undifferentiated shock. In addition, aspects of cardiac US are being used for the assessment of intravascular volume status and cardiac output and in the evaluation of dyspnea.

In cardiac arrest, US can detect ventricular motion in both asystole and pulseless electrical activity (PEA).102,103 In asystole, two studies have shown poor prognosis in the absence of sonographic ventricular activity.⁸⁴ Cardiac US can detect pseudoasystole by revealing ventricular fibrillation or coordinated cardiac contractions without a palpable pulse.^85,104 Use of cardiac US in PEA and near-PEA states can be diagnostic for pericardial effusion.⁸² Cardiac US can detect ventricular capture when the patient is paced, transcutaneously or by a transvenous pacer. US can also identify pneumothorax, another treatable cause of cardiac arrest.¹⁰³ Cardiac US is feasible during pulse checks and prehospital life support, as advanced cardiac life support guidelines suggest minimizing non–cardiopulmonary resuscitation intervals.^105–108

Emergency cardiac US is diagnostic for both medical and traumatic pericardial effusions.109,110 In patients with dyspnea, pericardial effusion is detected with excellent accuracy.¹¹¹ In trauma, use of cardiac US reduces time to operative intervention and reduces mortality in patients with penetrating cardiac injury.⁵⁰ Detection of effusions in blunt trauma has also been described. Patients with cardiac US performed by emergency physicians for pericardial effusion have significantly reduced hospital length of stay and charges.¹¹²

Cardiac US is used for detection of pericardial effusions, chamber enlargement, and global activity in chest pain syndromes.¹¹³ In chest pain, US has been studied for the evaluation of pericardial tamponade, pulmonary embolus, cardiogenic shock, aortic dissection, pneumothorax, and bony chest wall fracture.^114–116

US protocols have been developed to evaluate undifferentiated hypotension.41,117–119 Cardiac US windows with the addition of abdominal views can assess for effusion, global ventricular activity, ventricular chamber size, IVC size and respiratory change, peritoneal fluid, and abdominal aortic aneurysm to narrow the differential diagnosis. Sepsis is the most common diagnosis for patients with hyperdynamic ventricular activity.¹²⁰

Central pressures can be estimated by examination of the IVC size and collapsibility.121,122 Studies show that this technique has good accuracy in assessment of blood loss, hypovolemia, and congestive heart failure.^123,124 Correlation studies have shown moderate agreement between central venous pressure and IVC measurements, with actual cardiac qualitative assessment as good as or better than the IVC measurements.^125–129 The internal jugular vein measurement may correlate with central venous pressure,¹³⁰ and esophageal Doppler examination may also correlate with hemodynamic measurements.¹³¹

Cardiac US is also a procedural guide for placement of transvenous pacer wires and for pericardiocentesis. Transvenous pacer wires are often placed through central veins, and it can be difficult to place them into the right ventricular apex. US facilitates placement by imaging of the wires in real time as they pass through the tricuspid valve and approach the apex of the right ventricle. US can also document ventricular capture. The probe is placed in the subxiphoid space for both applications.

Abdominal Vascular Ultrasound

Emergency physicians use abdominal US to detect abdominal aortic aneurysm, another silent disease in patients with flank, abdominal, or back pain, and to evaluate unexplained hypotension in the older patient.132,133 The use of US to detect aortic dissection and occlusion is described as well.^134–136

The technique involves imaging of the aorta from the subxiphoid space to the umbilicus to evaluate for dilation above a diameter of 3 cm (Fig. 196-4). For the detection of infrarenal aneurysms, the technique should visualize the aorta from the diaphragm to the aortic bifurcation. Fusiform aneurysms are more common, but detection of saccular aneurysms requires both the transverse and longitudinal planes.¹³⁷ If an aneurysm is found, a peritoneal view of Morison’s pouch is performed to detect intraperitoneal fluid. Proximal iliac arteries may be followed if it is technically feasible or time allows.

Emergency physician use of US for abdominal aortic aneurysm detection has shown good accuracy compared with other imaging modalities and laparotomy.133,138–140 It also has management implications in older patients with lower back pain, in whom the elimination of the presence of abdominal aortic aneurysm can lead to other management decisions. Screening for abdominal aortic aneurysm in the ED with US has been shown to be effective.^141,142

Endovascular repair versus the more traditional open repair has become more popular.143,144 The detection of leaks (often called endoleaks) from the stent would require Doppler imaging and may require further imaging with computed tomography or magnetic resonance imaging.¹⁴⁴

Aortic dissection may be detected by a combination of abdominal and cardiac scanning.¹³⁶ A linear echogenic flap, anywhere across the lumen of the aorta, is suggestive of dissection, sometimes with the detection of different flows on either side of the flap by color Doppler scanning. The cardiac US examination can show unexplained pericardial effusion; a dilated aortic root; aortic insufficiency; and a linear echogenic flap seen in the ascending aorta, aortic arch (through a suprasternal notch), or descending aorta.

Aortic occlusion is another condition that may be detected by US.¹⁴⁵ Echogenic thrombus may fill the aorta and disrupt perfusion below the diaphragm with resulting pain, pallor, numbness, and reduction or absence of distal pulses. Clear identification of the borders and lack of Doppler flow in the abdominal aorta are characteristic of the syndrome.

Biliary Ultrasound

Biliary US to detect gallstones and associated cholecystitis was one of the early applications of US in emergency medicine.146–148 The sonographic technique involves a modified biplanar approach to the right upper quadrant. A complete evaluation includes visualization of the common bile duct. The diagnosis of cholelithiasis is made after identification of echogenic foci within the gallbladder lumen with shadowing (Fig. 196-5). Other image patterns include stones that will not shadow, sludge, and the wall echo sign of a gallbladder full of gallstones. Signs of cholecystitis include a dilated gallbladder, increased gallbladder wall thickness, sonographic Murphy’s sign, and pericholecystic fluid. A nonmobile stone in the gallbladder neck is highly suggestive of eventual cholecystitis.¹⁴⁹ A common bile duct larger than 6 mm in people younger than 60 years and smaller than 10 mm in elders may indicate choledocholithiasis. Biliary US is fast and accurate, with a sensitivity of 87 to 94% and a specificity of 82 to 96% in detection of gallstones, comparable to radiology ultrasonography.^150–153 Biliary US has replaced nuclear medicine testing.^148,154

Urinary Tract Ultrasound

Renal or urinary tract US can detect hydronephrosis or urinary retention. The lack of ionizing radiation and the rapidity of renal US make it an attractive option for the investigation of unexplained flank, back, or groin pain or abdominal mass.

Renal US includes biplanar views of the kidneys with emphasis on dilation of the calyceal system and pelvis of the respective kidney (Fig. 196-6). In addition, visualization of the bladder can diagnose secondary hydronephrosis from an obstructed bladder stone and may demonstrate nonobstructive bladder jets through the use of Doppler US. The windows for the two kidneys are similar to those of the trauma flank series, with the exception that the patient may be rolled on the opposite side so that the transducer may be placed more posteriorly on the back if necessary. The bladder view is performed suprapubically, and calculations of volume may be made with on-machine calculators or by formulas.

Renal US has a sensitivity of 83% and a specificity of 92% in detection of hydronephrosis (see Fig. 196-6).^155,156 Genitourinary tract obstruction protocols have great sensitivity in elimination of renal obstruction from a differential diagnosis.¹⁵⁷ Bladder US is useful for detection of a full bladder and the presence of a Foley catheter and for guidance during suprapubic aspiration or Foley placement.^{119–124,158–160}

Deep Venous Thrombosis Ultrasound

The swollen extremity often requires sonographic imaging to assess for DVT. Emergency physicians commonly use compression US to rule out DVT.125–128,161–165 The two-level compression technique involves visualization of the compressibility of the common femoral and popliteal veins. The three-level technique adds the junction of the superficial femoral and deep femoral veins (Fig. 196-7). Use of upper extremity veins is less common because Doppler US is needed for the subclavian vein, which is not compressible under the clavicle.¹⁶⁶

The accuracy of this technique ranges from 70 to 99%, depending on operator experience.164,167–169 Hospital charges and time in the ED are reduced for patients who have bedside venous US performed to rule out DVT.^170–172

Bernardi also investigated a whole-leg strategy versus a 2-point strategy in combination with a D-dimer test, which required 1-week follow-up with an abnormal level.¹⁷³ Both strategies were equivalent in detection of symptomatic DVT at 3-month follow-up. Depending on the skill of the sonographer, patient characteristics, and availability of follow-up, ED US may guide lower extremity DVT institutional protocols.

Thoracic and Tracheal Ultrasound

Thoracic applications include the detection of pleural effusion, pneumothorax, pneumonia, and interstitial edema.174,175 The technique of thoracic US uses a low-frequency probe to survey for pleural effusions and a high-frequency probe to detect pleural lines and related artifacts. Pleural fluid appears as an anechoic collection above the diaphragm (Fig. 196-8). In addition, a collapsed lung may be visualized as an echogenic floating structure. Normally, the parietal and visceral pleural lines slide against each other, and lack of sliding is the finding most consistent with pneumothorax (on M-mode, called the seashore sign). Additional findings of pneumothorax include the presence of horizontal artifacts called A-lines (on M-mode, called the stratosphere sign) and the absence of B-lines (vertical white lines from reverberation of air with fluid) at the parietal-visceral pleural line (Fig. 196-9).^176–179 Confounding factors include adhesions of the pleura, chronic obstructive pulmonary disease, prior pneumothorax, and mainstem bronchus intubation. A lung point sign is the edge of the pneumothorax where the lung is still adherent to the parietal pleura, and part of the image shows no sliding until the lung moves into the interspace with respirations.¹⁷⁷ The accuracy of US for detection of pneumothorax (sensitivity 100%, specificity 98%) is better than that of plain chest radiography in the acute setting, but there may be reduced accuracy after 24 hours.¹⁸⁰

Severe pneumonia is visualized as echogenic “liver-like” echogenicity as the lung accumulates fluid with consolidation.¹⁸¹ Peripneumonic collections are common and may indicate inflammation. The dynamic air bronchogram, hyperechoic areas within bronchi that move with respiration, usually within “heparinized” lung, has been described as another sign of alveolar consolidation.¹⁸²

Pulmonary edema is indicated by the presence of comet tails (B-lines), which are reverberation artifacts that reflect from the parietal pleural interface into the lung. Normally found in dependent areas of the lung, the widespread distribution of these artifacts in an apical lung may indicate increased lung congestion.183–185

Dynamic tracheal US for the confirmation of endotracheal intubation has relatively good sensitivity and specificity.186–188 The dynamic movement of the endotracheal tube creates a flutter through the recognized shadow of the airway, but static US seems to lack accuracy.^189,190 This technique may have a role in patients in cardiac arrest or with equivocal end-tidal carbon dioxide levels, and confirmation is significantly faster than with chest radiography in children.¹⁹⁰

Ocular Ultrasound

The eye is an excellent acoustic window, and short-duration gray scale US over a closed eyelid can visualize both the anterior and the posterior chamber well.191,192 The globe, pupillary size, and extraocular movements can be examined even with facial swelling.^193,194 Ocular US has been described for intraocular disease, such as retinal detachment (Fig. 196-10), retinal hemorrhage, vitreal hemorrhage, intraocular foreign body, dislocated lens, and retro-orbital hemorrhage.^{191,192,195,196} The sensitivity of ocular US for retinal detachment by emergency physicians is 100%, and the specificity is 83 to 92%.^197,198 In addition, the optic nerve sheath diameter can be measured behind the eye, reflecting intracranial pressure.^199–202 The sensitivity of such measurements ranges from 83% in children to 100% in adults.^199,203

Soft Tissue Ultrasound

Except in the hand and foot, US in soft tissue is straightforward because of the lack of air and bone in the skin and subcutaneous tissue. Soft tissue US is used to differentiate cellulitis from abscess, to detect foreign bodies and hernias, and to evaluate other soft tissue pathologic processes, including masses, pseudoaneurysms, and glands.204–208 A high-frequency linear transducer moves from normal skin to the abnormal area. Cellulitis or edema will cause an echogenic pattern with cobblestoning between fat lobules (Fig. 196-11). Abscesses are irregular hypoechoic to anechoic collections within the subcutaneous layer but may connect with the surface (Fig. 196-12). US is diagnostic in soft tissue disease for cellulitis, abscess, and necrotizing fasciitis.^{150–153,209,210} In the ABSCESS study, clinical examination had a sensitivity of 86% and specificity of 70%, whereas US had a sensitivity of 98% and specificity of 88%.²⁰⁵ In other studies, use of US changed management for half of adult patients and 22% of children with clinical cellulitis.^206,211 One study showed that incision and drainage is superior to US-guided aspiration in a cohort of patients with soft tissue infection in regard to resolution at 1 week (80% vs. 26%, respectively).²¹²

US can differentiate peritonsillar abscess from cellulitis and can be used for guidance of peritonsillar aspiration.213,214 It can also detect early Ludwig’s angina with abscess, dental abscess, epiglottitis, glandular abnormalities, and pseudoaneurysm in soft tissues and fascia of the face.^{207,208,215–217} US has also been used in various body areas, including the penis and scrotum, for signs of disruption or infection.^218,219

Detection of foreign bodies is characterized by variable echogenicity in the tissue with shadowing beneath the foreign body. Metal foreign bodies, such as bullets and intrauterine devices, have characteristically high-reflective echogenicity and ring-down artifacts. Bedside US has variable accuracy for detection of foreign bodies in simulated cases but better accuracy in true clinical settings.220–222 Use of a water bath may aid in the detection of superficial foreign bodies.²²³

Musculoskeletal Ultrasound

US has been particularly useful for joint effusion and muscle, tendon, and bone injury. US is excellent for detection of fluid in joints, confirmation of effusions, and guidance of drainage procedures.29,160,161,224–230 Joint effusions typically are anechoic or echogenic, depending on type and age (Fig. 196-13). Arthrocentesis of both the adult and pediatric hip, in addition to other joints, has been reported with good success.^229,231,232

Diagnosis of ligamentous injuries and muscle avulsion and hemorrhage has also been reported.224,233 Muscle and tendon abnormalities are detected by anechoic and heterogeneous abnormalities (Fig. 196-14). Detection is often assisted by movement of the limb. Tendons and their anisotropic longitudinal fibrils can be visualized near joints, with pathologic tears appearing as a discontinuity of the tendon. Muscles are hypoechoic with echogenic borders. Tears and hemorrhage are interruptions of this normal pattern.^224,234,235 Water bath techniques provide a better acoustic window for shallow tissue, such as fingers.²³⁶

The characteristic reflection of bone with immediate shadowing is used to identify normal bone and its contour. Fractures are seen as a defect in the bony cortex.46,224,237–240 The image of the cortex can be useful for guidance of fracture reduction.^241–243 Comparison with the contralateral side may also be helpful. Confirmation can be done by US imaging before and after reduction.²⁴⁴

US is accurate in the detection of fractures, joint effusions, bursitis, cysts, and hematomas.140,229,231,245–247 Prospective evaluation of finger fractures demonstrates good accuracy²²⁸ (Fig. 196-15). Other fractures studied include femur, sternal, rib, and forearm fractures.^{224,237–240}

Transcranial Doppler Ultrasound

Transcranial Doppler US has been used for detection of abnormal flow patterns in the brain and for detection and treatment of middle cerebral artery strokes. An advanced procedure, typically using a phased array transducer over a bone or orbital window in the skull, color Doppler and spectral Doppler scanning is performed at different levels of intracranial vessels for detection of abnormal patterns.³⁹

Testicular Ultrasound

Testicular scanning is an advanced US application that requires visualization of the normal and symptomatic testicle with a high-frequency probe. The testicular structures, including the normal homogeneity of the testicle, are evaluated, and Doppler scanning is performed for evaluation of normal venous and arterial flow (Fig. 196-16). Absent or decreased flow on the affected side indicates possible torsion, whereas increased flow indicates epididymitis. Experienced emergency physicians accurately diagnosed testicular pain with a sensitivity of 95% and specificity of 94% in a study of 36 patients, which included 3 patients with torsion.²⁴⁸

Abdominal Bowel Ultrasound

The use of bedside US for evaluation of appendicitis, diverticulitis, and other bowel disease is an area of increasing interest. There has been variable experience with the use of graded compression US to detect appendicitis (>6 mm), with reported sensitivity of 67% and specificity of 92% (Fig. 196-17).²⁴⁹ Whereas there is considerable effort looking at the use of US first and then computed tomography for appendicitis, the accuracy of emergency physician–performed US for appendicitis has been equivocal.^249–251 In women, endovaginal US can be used to rule out adnexal disease.⁹⁸

The use of US for diverticulitis, intussusception, volvulus, and small bowel obstruction has been reported.252–254 Thickening of the bowel, dilated bowel with fluid-filled loops, and changes in vascularity suggest disease. Tracing of the bowel to normality may also show cutoff points.

Hernias, described in the soft tissue section, may also be detected as masses in the ventral, inguinal, paramedian, femoral, and scrotal areas.²⁵⁵ Free air, with comet tails and artifacts in areas that are usually normal, such as between the liver and diaphragm, may also be detected in patients with suspected perforated viscus.²⁵⁶

Ascites, similar to traumatic free fluid in the sonographic appearance, will be much more apparent with tremendous amounts of free anechoic fluid, small echogenic liver, and outlined organs. Small amounts of ascites may be the first clue to abnormal pathologic states.

Pediatric Emergency Ultrasound

The use of US for children in the ED has two paths, one that mirrors the applications that have been used for adults and a second exploring the more specific pediatric abdominal applications.²⁵⁷ The use for patient management and accuracy can vary per application.

The FAST examination for evaluation of abdominal trauma in children is specific (98%), but the sensitivity is only 20%, making it difficult to use without further imaging or other testing.⁶⁷ In addition, specific pediatric abdominal applications that are common in the radiology suite have begun to be explored. Case reports and case series of intussusception, appendicitis, and pyloric stenosis have been reported.^{251,252,258–260}

Ultrasound for Procedural Guidance

In 2001, in response to the Institute of Medicine report To Err Is Human, the Agency for Healthcare Research and Quality (AHRQ) sanctioned a report on actions that may improve patient safety.261,262 The report contains a recommendation for US guidance for internal jugular central line insertion. Since then, the use of US for procedural guidance has expanded for many emergency procedures, especially vascular access, and is advocated for error reduction.²⁶³

Procedural guidance can be static or dynamic.²⁶⁴ Static guidance suggests that US has been placed over the anatomic area, and the area is marked while angle and distance information is noted. Dynamic guidance describes procedures performed with real-time US visualization of the needle entering the anatomic area on the monitor as well as on the patient.

There are two common axis approaches to vein cannulation: transverse, in which the vein appears as a circular structure on the screen; and longitudinal, in which the vein appears as a tubular structure along the width of the screen. In the transverse approach (also known as out of plane), the probe’s long axis is centered transverse (90 degrees) to the long axis of the anatomic area, guiding the needle to bisect the probe at its center, which gives centering and depth information (Fig. 196-18). In the longitudinal axis (also known as in-plane), the probe is placed along the long axis of the anatomic area, and the needle is introduced in the long axis of the probe, giving depth and trajectory information (Fig. 196-19). Whereas the short-axis approach is more popular with novices, the long-axis approach may be safer because of the visualization of the needle tip during the entire dynamic procedure.¹⁵⁰ Finally, an oblique axis has been described, essentially approaching the vessels at 45 degrees but visualizing the target vessels and surrounding structures.²⁶⁵

The most studied and most advocated use of US procedural guidance is for central line insertion.266–269 Both the AHRQ and the National Institute for Health and Clinical Excellence have recommended US guidance for central line insertion.^262,270 US guidance for internal jugular central line insertion can be recommended as a safe and best practice.²⁷¹

US permits the physician to assess the internal jugular for overlap with the carotid artery, vessel diameter, and presence of luminal clot or vessel obliteration.¹⁸⁶ Internal jugular central line insertion has been studied in the ED, intensive care unit, and radiology suite. In the ED, US-guided internal jugular cannulation is associated with decreased time to flashback and improved success in the difficult-stick patient, improved overall success rate and first attempt and overall rates, reduced time to insertion, and reduced complication rate.^268,272,273 The Valsalva maneuver and Trendelenburg position may assist in increasing the size of the cross-sectional area.²⁷⁴

US does not prevent posterior vein wall penetration as reported in case reports and simulated models.275,276 Adverse events (hematoma, arterial cannulation, pneumothorax, and unsuccessful placement) can occur in up to 20% of patients having US-guided internal jugular catheterization.^277–279

Femoral vein insertion has been studied in cardiac arrest patients, and improved cannulation rate and reduced complications have been reported.²⁸⁰ Several maneuvers can optimize the success rate of femoral vein cannulation, including the reverse Trendelenburg position and placement of the pressure on the iliac vein proximal to the femoral vein.^188,281,282

US does not contribute to procedural success in subclavian vein cannulation because of the lack of a convenient window for the subclavian vein under the clavicle. Laterally, toward the junction of the axillary vein and subclavian veins, the vein can be visualized in the chest wall.283,284 Although it may be cannulated there, the challenge is to insert the catheter through the pliable soft tissue of the anterior-superior chest.^191,284,285 The supraclavicular fossa is a window for central line insertion, and the subclavian and brachiocephalic veins may be imaged at this site.^192,286

US-guided central access decreases complications and attempts but did not improve success rates in pediatric critical care patients.²⁸⁷

Emergency physicians are able to use US to insert peripheral intravenous catheters in patients with difficult access with high success rates.193–195,288,289 Only one randomized study showed no differences in number of attempts, time to successful catheterization, or patient satisfaction.²⁹⁰ Veins that are large in width (0.4 cm) or at moderate depth (0.3-1.5 cm) have a higher success rate.²⁹¹ Nurses and ED technicians have also been taught to use US for peripheral venous guidance.^292–294

The use of one operator versus two operators has not been shown to increase success rates.²⁹⁵ US can facilitate peripheral vascular access by the Seldinger technique.²⁹⁶ Marking of the skin in its long axis while using the short axis has not increased success rates.²⁹⁷ Pediatric US-guided intravenous catheter placement in difficult-access pediatric patients has been shown to be more successful than traditional techniques.^298,299 Arterial access, including radial artery aspiration and cannulation, is more successful with US guidance.^300,301 US has confirmed intravascular location with a combination of B-mode and Doppler mode, in which the needle, guidewire, and catheter can be located by US.^302–304

Sonographic confirmation of intraosseous placement has also been described with detection of Doppler flow outside the bone and inside the marrow.305,306 Numerous other procedures using US guidance have been described in emergency practice (Table 196-2).

Out-of-Hospital Ultrasound: Disasters and Remote Settings

US has been used in the out-of-hospital, military battlefield, disaster, and international medicine settings. The use of US has been described in European and other settings by physicians in the out-of-hospital arena, including ground, helicopter, air, and space,9,317–323 and by paramedics for FAST and abdominal aorta examinations.³²⁴

The military forced development of small compact US machines and has been an extensive user of US in combat situations, including the frontline, combat support hospital, and tertiary hospital settings.9,11,325 US has been used in the Armenian earthquake of 1988, the Haitian earthquake of 2010, and other multiple casualty situations.^326–328

US interpretation may be enhanced by satellite and telesonography systems that allow remote guidance and interpretation.³²⁹ In remote and international low-resource settings, US has become the imaging test of choice for emergency care.^330,331

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