Herpes: Multiple small, discrete, punched-out ulcers on background of normal mucosa
CMV and HIV: 1 or more large, flat ulcers
HPV: Multiple papillary excrescences
EBV: Deep, linear ulcers
TOP DIFFERENTIAL DIAGNOSES
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Candida, reflux, or drug-induced esophagitis
PATHOLOGY
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Impaired immune surveillance: Radiation and chemotherapy render esophageal mucosa vulnerable to infection
CLINICAL ISSUES
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Odynophagia is most common presenting symptom
Related
Diagnostic Imaging_ Gastrointes - Michael P Federle
