Thyroiditis

Published on 02/03/2015 by admin

Filed under Endocrinology, Diabetes and Metabolism

Last modified 02/03/2015

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CHAPTER 35

Thyroiditis

1. Give the differential diagnosis for thyroiditis.

2. What causes acute thyroiditis?

3. How is acute thyroiditis managed?

4. Describe the four stages of subacute thyroiditis.

5. Summarize the natural history of subacute thyroiditis.

Subacute thyroiditis is probably viral in origin. Histologically, the inflammation is granulomatous. Although patients almost always recover clinically, serum thyroglobulin (Tgb) levels remain elevated, and intrathyroidal iodine content is low for many months (Fig. 35-1). Such findings suggest persistent subclinical abnormalities after an episode of subacute thyroiditis. Nonsteroidal antiinflammatory agents are first-line treatment in mild to moderate cases, whereas steroids may be needed when the condition is more severe. Patients requiring steroids are more likely to become hypothyroid at a later time. Up to 4% of patients have a second episode many years later.

6. What is the most common cause of thyroiditis?

7. Describe the clinical characteristics of autoimmune thyroid disease.

8. Does postpartum thyroiditis follow a different clinical course from that of other types of autoimmune thyroiditis?

9. How common is postpartum thyroiditis?

10. Which patients with postpartum thyroiditis should be treated?

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