The Cardiovascular System

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Chapter 10 The Cardiovascular Exam

A. Generalities

Cardiovascular examination is centered on five main components, all essential for making a diagnosis. This section discusses inspection, palpation, and percussion. Auscultation is addressed in two separate presentations.

B. General (Physical) Appearance

2 What aspects of general appearance should be observed in evaluating cardiac patients?

As suggested by Perloff, one should sequentially evaluate the following nine areas:

See Tables 10-1 and 10-2.

Table 10-1 Diagnostic Clues: Body and Facies, Gestures and Gait, Face and Ears

Body Appearance and Facies
image The anasarca of congestive heart failure
image The struggling, anguished, frightened, orthopneic, and diaphoretic look of pulmonary edema
image The tall stature, long extremities (with arm span exceeding patient’s height), and sparse subcutaneous fat of Marfan’s syndrome (mitral valve prolapse, aortic dilation, and dissection)
image The long extremities, kyphoscoliosis, and pectus carinatum of homocystinuria (arterial thrombosis)
image The tall stature and long extremities of Klinefelter’s syndrome (atrial or ventricular septal defects, patent ductus arteriosus, and even tetralogy of Fallot)
image The tall stature and thick extremities of acromegaly (hypertension, cardiomyopathy, and conduction defects)
image The short stature, webbed neck, low hairline, small chin, wide-set nipples, and sexual infantilism of Turner’s syndrome (coarctation of the aorta and valvular pulmonic stenosis)
image The dwarfism and polydactyly of Ellis-van Creveld syndrome (atrial septal defects and common atrium)
image The morbid obesity and somnolence of obstructive sleep apnea (hypoventilation, pulmonary hypertension, and cor pulmonale)
image The truncal obesity, thin extremities, moon face, and buffalo hump of hypertensive patients with Cushing’s syndrome
image The mesomorphic, overweight, balding, hairy, and tense middle-aged patient with coronary artery disease
image The hammer toes and pes cavus of Friedreich’s ataxia (hypertrophic cardiomyopathy, angina, and sick sinus syndrome)
image The straight lower back of ankylosing spondylitis (aortic regurgitation and complete heart block)
Gestures, Gait, and Stance
image The Levine’s sign (clenched fist over the chest of patients with an acute myocardial infarction)
image The preferential squatting of tetralogy of Fallot
image The ataxic gait of tertiary syphilis (associated with aortic aneurysm and regurgitation)
image The waddling gait, lumbar lordosis, and calves pseudohypertrophy of Duchenne’s muscular dystrophy (associated with hypertrophic cardiomyopathy and a pseudo infarction pattern on ECG)
Face and Ears
image Pulsatility of the earlobes (tricuspid regurgitation)
image Head bobbing (De Musset’s and Lincoln’s signs)
image The round and chubby face of congenital pulmonary stenosis
image The hypertelorism, pigmented moles, webbed neck, and low-set ears of Turner’s syndrome
image The round and chubby face of congenital valvular pulmonic stenosis
image The elfin face (small chin, malformed teeth, wide-set eyes, patulous lips, baggy cheeks, blunt and upturned nose) of congenital stenosis of the pulmonary arteries and supravalvular aortic stenosis—often associated with hypercalcemia and mental retardation.
image The unilateral lower facial weakness of infants with cardiofacial syndrome—this can be encountered in 5–10% of infants with congenital heart disease (usually ventricular septal defect); often noticeable only during crying.
image The premature aging of Werner’s syndrome and progeria (associated with premature coronary artery and systemic atherosclerotic disease)
image The drooping eyelids, expressionless face, receding hairline, and bilateral cataracts of Steinert’s disease (myotonic dystrophy, associated with conduction disorders, mitral valve prolapse)
image The epicanthic fold, protruding tongue, small ears, short nose, and flat bridge of Down syndrome (endocardial cushion defects)
image The dry and brittle hair, loss of lateral eyebrows, puffy eyelids, apathetic face, protruding tongue, thick and sallow skin of myxedema (associated with pericardial and coronary artery disease)
image The macroglossia not only of Down syndrome and myxedema, but also of amyloidosis (linked to restrictive cardiomyopathy, congestive heart failure)
image The paroxysmal facial and neck flushing of carcinoid syndrome (with pulmonic stenosis and tricuspid stenosis/regurgitation)
image The saddle-shaped nose of polychondritis (associated with aortic aneurysm)
image The tightening of skin and mouth, scattered telangiectasias, and hyperpigmentation/hypopigmentation of scleroderma (with pulmonary hypertension, pericarditis, and myocarditis)
image The flushed cheeks and cyanotic lips of mitral stenosis (acrocyanosis)
image The gargoylism of Hurler’s syndrome (associated with mitral and/or aortic disease)
image The short palpebral fissures, small upper lip, and hypoplastic mandible of fetal alcohol syndrome (associated with atrial or ventricular septal defects)
image The diagonal earlobe crease as a (questionable) marker of coronary artery disease (earlobe sign [also known as Frank’s sign])

Table 10-2 Diagnostic Clues: Eyes, Extremities, Skin, Thorax, and Abdomen

Eyes
image Xanthelasmhas of dyslipidemia and coronary artery disease (CAD)
image The enlarged lacrimal glands of sarcoidosis (restrictive cardiomyopathy, conduction defects, and, possibly, cor pulmonale)
image The cataracts and deafness of “rubella syndrome” (patent ductus arteriosus [PDA] or stenosis of the pulmonary artery)
image The stare and proptosis of increased central venous pressureimage The lid lag, stare, and exophthalmos of hyperthyroidism (tachyarrhythmias, angina, and high output failure)
image The conjunctival petechiae of endocarditis
image The conjunctivitis of Reiter’s disease (pericarditis, aortic regurgitation, and prolongation of the P-R interval)
image The blue sclerae of osteogenesis imperfecta (aortic regurgitation)
image The icteric sclerae of cirrhosis
image The Brushfield’s spots (small white spots on the periphery of the iris, usually crescentic and with an outward concavity, frequently but not exclusively seen in Down syndrome—endocardial cushion defects)
image The fissuring of the iris (coloboma) of total anomalous pulmonary venous return
image The dislocated lens of Marfan’s syndrome
image The retinal changes of hypertension and diabetes (CAD and congestive heart failure)
image The Roth spots of bacterial endocarditis
Extremities
image The cyanosis and clubbing of “central mixing” (right-to-left shunts, pulmonary arteriovenous fistulas, and drainage of the inferior vena cava into left atrium)
image The differential cyanosis and clubbing of PDA with pulmonary hypertension (the reversed shunt limits cyanosis and clubbing to the feet, but spares hands)
image The “reversed” differential cyanosis and clubbing of transposition (aorta originating from the right ventricle): hands are cyanotic and clubbed, but feet are normal
image The sudden pallor, pain, and coldness of peripheral embolization
image Osler’s nodes (swollen, tender, raised, pea-sized lesion of finger pads, palms, and soles) and Janeway lesions (small, nontender, erythematous or hemorrhagic lesions of the palms or soles) of bacterial endocarditis
image The clubbing, splinter hemorrhages of endocarditis
image The Raynaud’s of scleroderma
image The simian line of Down’s syndrome (atrial septal defect [ASD])
image The hyperextensible joints of osteogenesis imperfecta (aortic regurgitation)
image The nicotine finger stains of chain smokers (CAD)
image The leg edema of congestive heart failure
image The tightly tapered and contracted fingers of scleroderma, with ischemic ulcers and hypoplastic nails (often associated with pulmonary hypertension and myocardial disease, pericarditis, and valvulopathy)
image The arachnodactyly, hyperextensible joints (especially knees, wrists, and fingers), and flat feet of Marfan’s syndrome (associated with aortic disease and regurgitation)
image The ulnar deviation of rheumatoid arthritis (pericardial, valvular, or myocardial disease)
image The mainline track lines of addicts (tricuspid regurgitation, septic emboli, and endocarditis)
image The liver palms (thenar and hypothenar erythema) of chronic hepatic congestion
Skin
image The jaundice or hepatic congestion
image The cyanosis of right-to-left shunt
image The pallor of anemia and high output failure
image The bronzing of hemochromatosis (restrictive cardiomyopathy)
image The telangiectasias of Rendu-Osler-Weber (at times associated with pulmonary arteriovenous fistulae)
image The neurofibromas, café-au-lait spots, and axillary freckles (Crowe’s sign) of von Recklinghausen’s (pheochromocytomas)
image The symmetric vitiligo (especially of the distal extremities) of hyperthyroidism
image The butterfly rash of SLE (endo-myo- pericarditis)
image The eyelid purplish discoloration of dermatomyositis (cardiomyopathy, heart block, and pericarditis)
image The skin nodules and macules of sarcoidosis (cardiomyopathy and blocks)
image The xanthomas of dyslipidemia
image The hyperextensible skin (and joints) of Ehlers-Danlos (mitral valve prolapse)
image The coarse and sallow skin of hypothyroidism
image The skin nodules (sebaceous adenomas), shagreen patches, and periungual fibromas of tuberous sclerosis (rhabdomyomas of the heart and arrhythmias)
Thorax and Abdomen
image The thoracic bulges of ventricular septal defect/ASD
image The pectus carinatum, pectus excavatum, and kyphoscoliosis of Marfan’s syndrome
image The akyphotic and straight back of mitral valve prolapse
image The systolic (and rarely diastolic) murmurs of pectus carinatum, excavatum, straight back
image The barrel chest of emphysema (cor pulmonale)
image The shield chest of Turner’s syndrome
image The cor pulmonale of severe kyphoscoliosis
image The ascites of right-sided or biventricular failure
image The hepatic pulsation of tricuspid regurgitation
image The positive abdominojugular reflux of congestive heart failure

C. The Arterial Pulse

Evaluation of the arterial pulse is a time-honored method of bedside examination. It can still provide valuable cardiovascular information. In selective processes (such as tamponade, aortic valve disease, and hypertrophic cardiomyopathy), it can even prove essential for securing a diagnosis. Yet, assessment of the characteristics of the arterial pulse requires skill and practice, and at times can be frustrating. It is worth the effort, though, and thus deserves attention, even in our times of intra-arterial monitoring.

33 What is the diagnostic significance of a pulsus bisferiens?

It usually reflects moderate to severe aortic regurgitation (with or without aortic stenosis), but can also occur in other high output states. In aortic regurgitation, however, the double pulse is not only palpable, but sometimes is even audible. For example, it can be detected as: