Syndrome of Spleen-Qi deficiency

Published on 09/02/2015 by admin

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1. Syndrome of Spleen-Qi deficiency

Manifestations

Main symptoms

Poor appetite, fullness in the stomach and distension of the abdomen after eating, soft stool, tiredness and weakness of the limbs. These symptoms start and get worse under conditions of changing diet or after taking heavy food.

Secondary symptoms

Heaviness of the limbs, sallow complexion, prolapse of the internal organs (e.g. uterus, stomach and rectum), large amount of leukorrhea, edema, heavy menstruation, poor concentration or inability to study and memorize things.

Tongue

Pale tongue (may be flabby with teeth marks in a chronic severe case) with a thin white coating.

Pulse

Weak or soft in general.

Associated disorders in western medicine

Chronic diseases and disorders of digestion, metabolism and immune function, such as chronic gastric ulcer, duodenal ulcer, food allergy and intolerance, hypotension, hypoglycemia, hypothyroidism, diabetes, chronic fatigue syndrome and prolapse of organs.

Analysis of the syndrome

Weakness of Spleen-Qi is often seen in people who have a poor constitution or suffer from chronic diseases, have the wrong diet or have been taking medication for too long. It is often seen in elderly people.
• When Spleen-Qi is impaired, the function of transportation and transformation of the Spleen is disturbed. Patients may have poor appetite (even nausea and vomiting) when the Stomach-Qi is unable to descend.
• Soft stool (even diarrhea) may appear when the Spleen-Qi sinks instead of rising.
• Since the wrong diet or heavy food places an extra burden on the Spleen and Stomach, these symptoms may start or get worse in these conditions.
• Since the Spleen controls the muscles, Spleen-Qi deficiency may weaken the strength of the muscles and cause tiredness, heaviness of the limbs and prolapse of the internal organs.
• When the Qi is too weak to push the water to circulate in the body, there may be edema, diarrhea or a feeling of heaviness in the body.
• When Spleen-Qi is not able to control circulation of blood in the blood vessels, a large bleed that is light in color may occur.
• When Spleen-Qi is not able to control transportation of the food essence, leakage may present, manifested as a large amount of leukorrhea, unstable plasma glucose and glucose, and protein or blood in the urine.
• A pale tongue with tooth marks indicates Qi deficiency in the Middle-Jiao, and the tongue coating shows the degree of accumulation, damp-phlegm, damp-heat or phlegm-heat. A soft or weak pulse obviously indicates deficiency of the Spleen-Qi. If there is accumulation in the Middle-Jiao, a full or forceful pulse may show in the second position on the right side.

Treatment principle: Tonify the Spleen-Qi and regulate the Middle-Jiao

Herb selection principles and formula composition strategies

• First, herbs that enter the Spleen and Lung meridians and have the function of tonifying the Spleen-Qi are selected.
• Second, herbs that regulate the Qi movement and water metabolism in the Middle-Jiao, and therefore strengthen the function and reduce the cloying nature of the tonifying herbs, are selected.
• Third, herbs that ascend the Spleen-Qi and herbs that treat the accompanying symptoms are selected.

Structure of the formula and selection of herbs

Chief: Tonify the Spleen-Qi directly

Ren Shen ( Ginseng radix)

Ren Shen is sweet and slightly bitter, and enters the Spleen and Lung meridians. It can strongly tonify the Spleen-Qi and the Source-Qi. It is used as chief in the formula to treat severe conditions of Qi deficiency or critical conditions of Qi collapse. Except for Xi Yang Shen ( Panacis quinquefolii radix), all of the Ren Shen products are warm in nature. It is so strong in tonifying Qi that it can produce warmth in the body, and therefore should be used with caution in patients who suffer from Yin and blood deficiency accompanied by Qi deficiency. In most cases of Spleen-Qi deficiency, especially in chronic conditions, a large dosage of Dang Shen ( Codonopsis radix) is often used as an effective substitute for Ren Shen.

Dang Shen ( Codonopsis radix)

Dang Shen is sweet and neutral, and enters the Spleen and Lung meridians. It is effective for tonifying the Spleen-Qi and the Lung-Qi. Its function is much gentler than that of Ren Shen. The strong point of this herb is that, as it is not heavy and sticky, and does not generate heat and dryness in the body, it is more suitable to be selected in a formula to treat chronic, mild cases of Spleen-Qi and Lung-Qi deficiency. As it can also generate the Yin and body fluids, it is also used for both Qi and Yin deficiency.

Huang Qi ( Astragali radix)

Huang Qi is sweet and warm, and enters the Spleen and Lung meridians. It can strengthen the Middle-Jiao, tonify the Spleen-Qi and thus treat Spleen-Qi deficiency. Compared with Dang Shen ( Codonopsis radix), Huang Qi is sweeter and warmer, and its function of tonifying the Spleen-Qi is stronger. Its specific action is to tonify the Qi, raise the Yang-Qi of the Spleen and strengthen the muscles. It is selected as chief in the formula to treat sinking of Spleen-Qi, which manifests as chronic diarrhea, prolapsed internal organs, weakness and heaviness of the limbs and tiredness. It is also used as chief in formulas that promote wound healing after surgical operations or trauma.

Gan Cao ( Glycyrrhizae radix) and Yi Tang ( Maltose)

Gan Cao is sweet and neutral, and enters all meridians. Yi Tang is sweet and slightly warm, and enters the Spleen meridian. Although they are mild ingredients, they are used in specific conditions as chief in the formula to treat Spleen-Qi deficiency. The moderate tonifying action is the most important characteristic of these two substances. They can be used for mild deficiency of Spleen-Qi, or for chronic conditions of Spleen-Qi deficiency when the body is too weak to bear strong tonification. As sweetness may moderate tension and ease muscles, these substances can be used in a reasonably large dosage to treat acute abdominal cramp and muscular pain due to weakness of the Spleen and attack by the Liver.

Deputy: Tonify the Spleen-Qi; promote Qi movement and water metabolism in the Middle-Jiao

Bai Zhu ( Atractylodis macrocephalae rhizoma)

Bai Zhu is sweet and warm, and enters the Spleen meridian. It can tonify the Spleen-Qi directly and its bitter and warm property can dry dampness. It is often selected as deputy in the formula to enhance the ability of the chief as well as to dry dampness in the Middle-Jiao. It can effectively treat poor appetite, fullness in the stomach, distension in the abdomen, diarrhea and heaviness of the limbs.

Shan Yao ( Dioscoreae rhizoma)

Shan Yao is neutral and sweet, and enters the Spleen meridian. It can either tonify the Spleen-Qi or stabilize the Yin. It is especially selected in the formula as deputy to enhance the ability of the chief to tonify the Qi and treat both Qi and Yin deficiency in the Middle-Jiao. Shan Yao also possesses a slightly astringent property, which is helpful in stopping diarrhea. Furthermore, this herb also enters the Lung and Kidney meridians, and is often applied to tonify and stabilize the Qi and Yin of these organs. The common symptoms are lack of appetite, fatigue, loose stool, shortness of breath, thirst and sweating.

Assistant: Regulate the Middle-Jiao, treat the accompanying symptoms and reduce the side effects of the chief and deputy herbs

Fu Ling ( Poria)

Fu Ling is neutral and bland, and can gently tonify the Spleen-Qi or eliminate dampness in the Middle-Jiao. As the function of Fu Ling is gentle, it can be used for a long period of time in chronic and mild syndromes of Qi deficiency of the Spleen. Moreover, Fu Ling can promote urination and leach out dampness from the Lower-Jiao, and therefore treat leukorrhea or reduce the cloying side effect of the sweet tonifying herbs.
As Fu Ling can also tonify the Heart-Qi, it is used for calming the mind. It is particularly useful for children with mild Heart-Qi and Spleen-Qi deficiency as it does not have a strong taste.

Bai Bian Dou ( Dolichoris lablab semen)

Bai Bian Dao is sweet and slightly warm. It has a gentle function of tonifying the Spleen-Qi, and is neither dry nor moist. It is particularly suitable for use in formulas to treat chronic mild deficiency of the Spleen-Qi or for use in the recovery period after chronic diseases when the condition of the patient is too weak to accept strong tonification. As Bai Bian Dou has a gentle astringent property, it is often used for diarrhea or soft stools caused by Spleen-Qi deficiency.

Zhi Gan Cao ( Glycyrrhizae radix preparata)

Besides directly tonifying the Spleen-Qi, the moderate nature of Zhi Gan Cao is often used in formulas to reduce the side effect of harsh herbs, such as herbs that stimulate the Qi or remove food or phlegm. It turns a quick action of herbs into a steady and constant action. It is also used to harmonize herbs that move in different directions and work on different levels. The dosage of Zhi Gan Cao should be low in cases of dampness accumulation as its sweet property has the tendency to retain dampness.

Ban Xia ( Pinelliae rhizoma) and Chen Pi ( Citri reticulatae pericarpium)

Ban Xia is pungent and warm, and enters the Spleen and Stomach meridians. It can soothe the Stomach-Qi and eliminate phlegm. Chen Pi is pungent, bitter and warm, and enters the Spleen and Lung meridians. It can regulate the Qi and remove phlegm. These two herbs are often used as assistants in formulas to regulate the Qi in the upper abdomen and reduce fullness and distending sensations that are caused by Spleen-Qi deficiency or by the heavy and cloying nature of tonifying herbs. They can therefore accelerate food and water transportation and transformation in the Middle-Jiao.

Mu Xiang ( Aucklandiae radix)** and Sha Ren ( Amomi xanthioidis fructus)

Mu Xiang and Sha Ren are pungent and warm, and enter the Spleen meridian. They are often used as assistants in formulas to regulate the Qi in the lower abdomen and reduce distension and abnormal bowel movement, which are caused by Spleen-Qi deficiency or by the heavy and cloying nature of tonifying herbs. In this way, they can accelerate food and water transportation and transformation in the Middle-Jiao.

Hou Po ( Magnoliae cortex)

Ho Po is pungent, bitter and warm. It enters the Lung, Stomach, Spleen and Large Intestine meridians. Since pungent and warm have an ascending tendency, and bitterness has a descending tendency, this herb can regulate the Qi in the Upper-, Middle- and Lower-Jiao, and remove dampness, food and phlegm accumulation. It can effectively treat fullness and distension.

Sheng Ma ( Cimicifugae rhizoma) and Chai Hu ( Bupleuri radix)

Sheng Ma is sweet, pungent and slightly cold, and enters the Spleen, Stomach, Lung and Large Intestine meridians. Chai Hu is bitter and neutral, and enters the Liver and Gall Bladder meridians. These two herbs have an ascending property. They are mainly used as assistants in formulas to ascend the Spleen-Qi in the treatment of prolapse of the internal organs and chronic diarrhea caused by Spleen-Qi deficiency. However, they only bring about an effective result in combination with tonifying herbs in the same formula, such as Huang Qi ( Astragali radix).

Envoy: Harmonize the herbs in the whole formula in the aspects of temperature, taste, working directions and levels, and characteristics

Zhi Gan Cao ( Glycyrrhizae radix preparata)

Since all the chief herbs enter the Spleen meridian and focus on tonifying the Spleen-Qi, it is not necessary to use an envoy as guide. However , Zhi Gan Cao often serves as envoy to harmonize the whole formula. It harmonizes herbs that move in different directions and works on different levels. The dosage of Zhi Gan Cao should be low in cases of dampness accumulation as its sweet property has the tendency to retain dampness.

Common accompanying symptoms and treatment

Poor appetite and nausea: use Ban Xia ( Pinelliae rhizoma) and Chen Pi ( Citri reticulatae pericarpium) to soothe the Stomach-Qi and to promote digestion.
Distension of the abdomen: use Sha Ren ( Amomi xanthioidis fructus) to reduce the stagnation of Qi and use Da Fu Pi ( Arecae pericarpium) to reduce the Qi and dampness accumulation.
Diarrhea due to Qi deficiency: use Fu Ling ( Poria), Bai Zhu ( Atractylodis macrocephalae rhizoma) and Bai Bian Dou ( Dolichoris lablab semen) to tonify the Spleen-Qi and transform the dampness. For chronic diarrhea, use Lian Zi ( Nelumbinis semen) to bind up the intestines and stop diarrhea.
Distending pain of the abdomen: use Mu Xiang ( Aucklandiae radix)** to regulate the Qi and relieve the pain.
Cold sensation in the abdomen: use Xiao Hui Xiang ( Foeniculi fructus) to regulate the Qi and warm the Middle-Jiao.
Accumulation of food: use Mai Ya ( Hordei fructus germinatus), Shen Qu ( Massa medicata fermentata) and Shan Zha ( Crataegi fructus) to promote digestion.
Constipation: use Mai Men Dong ( Ophiopogonis radix) and Dang Gui ( Angelicae sinensis radix) to moisten the intestines and promote bowel movement.
Edema: use Huang Qi ( Astragali radix) and Fu Ling ( Poria) to tonify the Qi and reduce edema.
Large amount of leukorrhea: use Shan Yao ( Dioscoreae rhizoma) and Che Qian Zi ( Plantaginis semen) to eliminate the dampness in the Middle-Jiao.
Heaviness of the limbs due to Qi deficiency and obstruction of water metabolism: use Huang Qi ( Astragali radix) to tonify the Qi and promote water metabolism; use Fang Feng ( Saposhnikoviae radix) and Qin Jiao ( Gentianae macrophyllae radix) to eliminate the dampness from muscles.
Weakness of the limbs: use Huang Qi ( Astragali radix), Chai Hu ( Bupleuri radix) and Sheng Ma ( Cimicifugae rhizoma) together to tonify and ascend the Spleen-Qi so as to strengthen the muscles.
Excessive pensiveness and worry: use Fu Shen ( Poriae cocos pararadicis), Bai Zi Ren ( Platycladi semen), Bai He ( Lilii bulbus), Long Yan Rou ( Longanae arillus) and Zhi Gan Cao ( Glycyrrhizae radix preparata) to calm the mind and tonify the Spleen.
Depression where Spleen fails to support the Heart and Lung: use Dang Shen ( Codonopsis radix), Bai He ( Lilii bulbus), Mai Men Dong ( Ophiopogonis radix) and Wu Wei Zi ( Schisandrae fructus) to tonify and stabilize the Heart and Lung.
Spontaneous sweating: use Huang Qi ( Astragali radix), Bai Zhu ( Atractylodis macrocephalae rhizoma) and Wu Wei Zi ( Schisandrae fructus) to tonify and stabilize the Spleen-Qi and stop sweating.

Examples of classical formulas

Si Jun Zi Tang (Four-Gentlemen Decoction) B9780702031328000116/if1.jpg is missing

Source: Tai Ping Hui Min He Ji Ju Fang B9780702031328000116/if2.jpg is missing

Composition

Ren Shen ( Ginseng radix) 10 g
Bai Zhu ( Atractylodis macrocephalae rhizoma) 9 g
Fu Ling ( Poria) 9 g
Zhi Gan Cao ( Glycyrrhizae radix preparata) 6 g

Analysis of the formula

Si Jun Zi Tang is a principal formula to tonify the Spleen-Qi and treat the syndrome of Spleen-Qi deficiency. Although there are only four herbs in this formula, it shows the basic principle and strategies to tonify the Qi. Many of the other formulas that tonify the Qi are developed from this formula.
Ren Shen, the chief, can strongly and directly tonify the Spleen-Qi. (In a chronic case, Dang Shen ( Codonopsis radix) is frequently used instead of Ren Shen.)
Bai Zhu serves as deputy. On the one hand, it can tonify the Spleen-Qi and reinforce the action of the chief to treat Qi deficiency; on the other hand, it can dry dampness in the Middle-Jiao, which often coexists when Qi is deficient.
Fu Ling serves as assistant, and again aids the action of tonifying the Qi of the Spleen. Moreover, it can drain dampness and assist the deputy to treat the coexisting disorder. By eliminating dampness, this herb is able to reduce the cloying nature of the other three sweet herbs to ensure that they do not put an extra burden on the Spleen and their sweet taste does not generate dampness in this condition. Fu Ling moves downwards and thus can reduce the distension of the abdomen; this is the reason that there is no herb in this formula to promote the Qi movement in the Middle-Jiao.
Zhi Gan Cao is sweet, and can tonify the Spleen-Qi as well as harmonize and integrate the herbs in the formula. Thus it serves as both assistant and envoy.

Commentary on strategies

This formula is based on a very balanced structure.
• Reinforcing and reducing procedures are used at the same time; stabilization (tonifying action) and movement (drying and drainage action) coexist in one formula. However, the main action of the formula is stabilization.
• The four herbs in the formula are all moderate in nature, neither hot nor harsh, matching the cultural characteristics of Chinese gentlemen, hence the name of this formula – Four-Gentlemen Decoction.
• Although there are only four herbs in this formula, they indicate the basic strategies for treating Spleen-Qi deficiency. It is therefore considered to be the principal formula to tonify the Spleen-Qi.

Shen Ling Bai Zhu San (Ginseng, Poria and Atractylodes Macrocephala Powder) B9780702031328000116/if3.jpg is missing

Source: Tai Ping Hui Min He Ji Ju Fang B9780702031328000116/if4.jpg is missing

Composition

Ren Shen ( Ginseng radix) 10 g
Bai Zhu ( Atractylodis macrocephalae rhizoma) 10 g
Fu Ling ( Poria) 10 g
Shan Yao ( Dioscoreae rhizoma) 10 g
Zhi Gan Cao ( Glycyrrhizae radix preparata) 10 g
Bai Bian Dou ( Dolichoris lablab semen) 7.5 g
Yi Yi Ren ( Coicis semen) 5 g
Lian Zi ( Nelumbinis semen) 5 g
Sha Ren ( Amomi xanthioidis fructus) 5 g
Jie Geng ( Platycodi radix) 5 g

Analysis of the formula

This formula tonifies the Spleen-Qi and transforms dampness from the Middle-Jiao. It treats the syndrome of Spleen-Qi deficiency with obvious accumulation of dampness in the Middle-Jiao, and at the same time treats deficiency of Lung-Qi due to Spleen-Qi deficiency. The symptoms are chronic diarrhea, weakness of limbs, weight loss, a low and soft voice and shortness of breath. A pale tongue with a moist white coating and a soft and slow pulse indicate the presence of dampness with Qi deficiency.
This formula can be considered as a variation of Si Jun Zi Tang (Four-Gentlemen Decoction).
Ren Shen is used as chief to strongly tonify the Spleen-Qi.
• Among the deputy herbs, Bai Zhu is used to tonify the Spleen and dry the dampness; Shan Yao is used to strengthen the Spleen-Qi and stabilize the Spleen-essence which has been lost due to chronic diarrhea; Zhi Gan Cao is used in quite a large dosage to aid the strength of the herbs that tonify the Spleen-Qi, hence its use as deputy in this formula.
• Among the assistants, Fu Ling is used to transform dampness and tonify the Spleen-Qi; Bai Bian Dou and Yi Yi Ren are selected to leach out dampness. The astringent Lian Zi is used together with Shan Yao and Bai Bian Dou to stabilize the Spleen-Qi and to stop diarrhea. Sha Ren is used to promote the Qi movement and eliminate dampness.
Jie Geng serves as envoy as it enters the Lung meridian and has an ascending nature. It is able to lead the Spleen-Qi to ascend to the Lung and thereby tonify the Lung-Qi.

Commentary on strategies

This formula demonstrates the treatment of a complicated case resulting from Spleen-Qi deficiency.
• It particularly presents the strategies of treating diarrhea, e.g. to dry the dampness by using warm and bitter herbs such as Bai Zhu; to leach out dampness by using bland and sweet herbs such as Fu Ling and Yi Yi Ren, which is called to stop diarrhea by promoting urination, and to directly stop diarrhea by using astringent Lian Zi, Bai Bian Dou and Shan Yao.
• This formula also shows an example of tonifying the Lung-Qi by using Jie Geng with the herbs that tonify the Spleen. This method is called to cultivate the earth to generate the metal. It belongs to the indirect tonifying method.

Bu Zhong Yi Qi Tang (Tonify the Middle and Augment the Qi Decoction) B9780702031328000116/if5.jpg is missing

Source: Pi Wei Lun B9780702031328000116/if6.jpg is missing

Composition

Ren Shen ( Ginseng radix) 9 g
Huang Qi ( Astragali radix) 12 g
Bai Zhu ( Atractylodis macrocephalae rhizoma) 9 g
Zhi Gan Cao ( Glycyrrhizae radix preparata) 3 g
Dang Gui ( Angelicae sinensis radix) 6 g
Chen Pi ( Citri reticulatae pericarpium) 6 g
Sheng Ma ( Cimicifugae rhizoma) 3 g
Chai Hu ( Bupleuri radix) 3 g

Analysis of the formula

In this formula:

Huang Qi is able to raise the Qi and Yang of the Spleen. Together with Ren Shen, it can strongly tonify the Spleen-Qi. These two herbs serve as chief.
Bai Zhu, the deputy, strengthens the Spleen-Qi and dries dampness in the Middle-Jiao.
• There are several assistants: Dang Gui is able to tonify the blood, which is weakened in conditions of severe Qi deficiency; Chen Pi can regulate the Stomach-Qi and promote digestion so as to assist the herbs that tonify the Spleen; it can also reduce the cloying properties of the tonifying herbs. Sheng Ma and Chai Hu can raise the Qi and Yang from the Middle-Jiao in the presence of Huang Qi. They can strongly enhance the effect of Huang Qi in raising the Qi and Yang.
• Zhi Gan Cao serves as assistant as well as envoy. As assistant, it tonifies the Qi of the Middle-Jiao; as envoy, it harmonize the herbs in the formula.

Commentary on strategies

This is a well-organized formula. It is an integration of tonifying Qi and blood, regulating Qi and raising Qi; therefore it can treat a complicated condition due to Spleen-Qi deficiency.
• It shows the method of raising Qi by using Huang Qi, Sheng Ma and Chai Hu together.
• With regard to composition, this formula can be considered a variation of Si Jun Zi Tang, the principal formula for tonifying the Spleen-Qi. Compared with Si Jun Zi Tang, the downward-moving Fu Ling is substituted by Huang Qi. This suggests that this formula is much stronger in tonifying and ascending the Qi.
• Moreover, this formula demonstrates the strategy of dealing with the relationship between Qi and blood in severe Qi deficiency by using Dang Gui.

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