Chapter 8 Staged Interpolation Flaps
Interpolation flaps demand exquisite planning and execution. In return, their sophistication offers rich rewards with a highly vascularized covering that may resurface complex defects, provide tissue bulk, nourish free cartilage grafts, and restore lining or contour as needed. The terms axial, indirect, interpolation, and staged flaps are synonymous and all are variations of transposition repairs. All interpolation flaps have these shared features: (1) vascular pedicle based on a named artery and or its tributaries, (2) donor location distant and noncontiguous from the defect, and (3) two or more stages for completion (stage I for flap creation and closure, stage II for pedicle division, and often additional stages for revisions).
The success of these flaps is dependent on adhering to three key principles. First, all margins must be definitively cancer free. Second, these flaps should be considered as heavy surface coverings (skin, subcutis, muscle) and a stable infrastructure must exist to support them. A large nasal defect, for example, cannot simply be covered without stable cartilage support and mucosal lining. Third, optimal repairs often require the reconstruction of an entire subunit.1 Wounds that consume 50% or more of a subunit are best restored in total. All patients with staged flaps require extensive preoperative consultation. Multiple visits and revisions, temporary physical deformities, and intensive wound care, as well as substantial activity and work restrictions, are the rule in staged repairs. In exchange for this demanding regimen, however, are surgical results that have no equal. This chapter will discuss techniques for (1) paramedian forehead flap, (2) cheek-to-nose interpolation flap, and (3) Abbé or lip-switch flap as applied to skin cancer reconstruction.
PARAMEDIAN FOREHEAD FLAP (PFF), STAGE I
Indication
The paramedian forehead flap (PFF) is a workhorse in facial reconstruction. Although it may close any wound on the central face, its best application is to the distal nose (tip, ala, and columella) where tissue thickness and sebaceousness are closely matched by forehead skin.2 The PFF is ideal for recreating the convexity and projection of the nasal tip. Subtotal nasal tip and/or alar defects may be candidates for the PFF. Proximal wounds on the nasal dorsum, sidewall, nasal root, and medial canthus have inherently thinner skin and may be incongruous for the much thicker PFF unless a substantially deep defect is present.
Anatomy
The primary and secondary vascular supply to the PFF is the supratrochlear (internal carotid system) and dorsal nasal artery (external carotid system), respectively. The supratrochlear artery (SA) is reliably located at the medial border of the eyebrow, 1.5–2 cm from the facial midline. At the medial eyebrow, a glabellar crease (if present) delineates where the SA crosses the superior orbital rim to enter the forehead (Figure 8.1). Below the orbital rim, the SA lies deep to the periorbital muscles (orbicularis oculi and frontalis). Above the rim, however, the SA pierces the frontalis muscle and ascends superficially into the forehead, sandwiched between the frontalis muscle below and the subcutis above. Consequently, to preserve the SA near the orbital rim, dissection must be below the frontalis muscle and deep fascia.
Flap Design
The ideal PFF is an aesthetic covering that restores normal contour and symmetry without creating a shapeless blob. Table 8.1 discusses the critical design issues in a PFF. The covering provided by a PFF requires a stable nasal infrastructure (cartilage support and mucosal lining). Structural cartilage grafts (SCG) to prevent nasal valve collapse and alar rim contraction are usual considerations in PFF repairs. More neglected, however, are SCG that restore contour to the nasal supratip. Contour grafts should be considered in patients that have thick nasal tip skin and supratip defects (Figure 8.2). Without a contour graft in these patients, a PFF alone may be insufficient to restore normal tip projection.3
DEFECT CONSIDERATIONS | COMMENTS |
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Does this defect require lining support? | Replacing lining may require intranasal mucosal flaps prior to PFF execution. |
Does this defect need cartilage support? | Cartilage grafts may be replacement or structural in nature. Replacement grafts restore missing cartilage or bone. Structural grafts add to stability and contour, and prevent tissue contraction to an intact cartilage infrastructure. |
Is the PFF sufficient to close this wound? | PFF may be combined with regional flaps, free cartilage grafts, and split- or full-thickness skin grafts for defects that extend onto multiple subunits. |
Does the residual subunit need to be excised? | Cosmesis is often superior when entire subunits are resurfaced. |
FLAP CONSIDERATIONS | COMMENTS |
---|---|
Has there been previous surgery at the proposed pedicle site? | Normal vascular anatomy may no longer be reliable and Doppler identification of a viable artery may be needed. |
Does the flap template accurately account for the 3-dimensional contour of the nose and infratip? | A flexible template material (suture foil wrap, soft foam, Duoderm) is essential for accurately moulding the template design. Two-dimensional defect measurements are inadequate. |
Does the forehead’s vertical height (from orbital rim to anterior frontal hairline) provide adequate length to reach the defect? | A short forehead height may require modifications to the template design and/or pedicle to optimize flap extension. |
Measurements of the defect must be accurate, neither over- nor undersized for the wound. The PFF template should be measured after the residual subunit has been outlined, but prior to the excision of any remaining skin (Figure 8.3). This avoids an artificially enlarged dimension from a retracted wound edge. A template should also reflect the 3-dimensional nature of the nose, especially if a defect extends to the infratip, columella, and ala (Figure 8.4a). If the vestibular mucosa is missing, the PFF may be extended and turned down to provide nasal lining. The soft nasal triangle, however, is best approached with second intention as the PFF, even when skeletonized, will never match the thin, soft concavity in this area (Figure 8.4b). Whenever possible, the unaffected contralateral side should be used as a template to restore symmetry. A right-sided nasal tip and ala wound, for example, should be repaired based on the normal left tip and ala.
Figure 8.4 (a) Complex Mohs defect of the nasal tip, soft triangle, and medial ala, necessitating a 3-dimensional design. (b) Paramedian forehead flap designed to cover complex nasal tip and ala defect except for the nasal soft triangle, which is best recreated with second intention healing (see Figure 8.13b for long-term results).
The vertical height of the forehead (from orbital rim to anterior frontal hairline) will determine the potential reach of this flap, and may be estimated by using a suture. If the vertical length is inadequate (short forehead height relative to distal defect), then the modifications listed in Table 8.2 will significantly extend a flap’s distal reach.
FLAP DESIGN MODIFICATIONS | COMMENT |
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Vertical extension of flap into the anterior frontal scalp | Potential transfer of terminal hairs onto the nasal defect. |
Potential disruption of frontal hairline and scarring alopecia if donor site closure is not complete. | |
Extension of flap lateral to midline | Potential compromise of vascular supply to lateral flap extension. |
Potential donor site morbidity with eyebrow elevation (scar contraction with second intention or distortion with complete closure). |
PEDICLE MODIFICATIONS | COMMENT |
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Keeping width of pedicle at its base between 1.0–1.5 cm | Wider pedicles (> 1.5 cm) limit flap mobility. |
Wider pedicles increase vascular strangulation during flap rotation toward the distal defect. | |
Mobilizing base of pedicle below superior orbital rim | Requires subperiosteal elevation of entire medial brow complex off of the superior orbital rim and arcus marginalis. |
May extend flap reach by at least 2 cm. | |
Incorrect elevation and undermining may lead to periorbital trauma and compromise vascular pedicle (supratrochlear artery). | |
Pedicle division at stage II will require eyebrow repositioning for bilateral symmetry. | |
Relaxing incision at medial base of pedicle (toward glabella and nasal root) | Releases dermal attachments at the pedicle base that may enhance flap mobility. |
Incision must not extend past superficial dermis. | |
DEFECT MODIFICATIONS | COMMENT |
Temporary alar suspension stitch | Suture is passed through the alar cartilages (if present) onto the glabella above. This suspends the nasal tip superiorly to meet the forehead flap, effectively extending flap reach. Suture is then removed at time of pedicle division. |
Prominent suture reaction at the glabella is predictable. | |
Potential for weakening the alar cartilage integrity with excessive superior suspension. |
Design considerations for the pedicle include its position and width. Identifying the SA pedicle may be done clinically, by using the anatomic landmarks mentioned earlier, or definitively by confirming with a manual Doppler (8–10 MHz frequency). The pedicle width, therefore, rarely needs to be greater than 1.5 cm.4 Wider pedicles in fact are counterproductive and restrict flap mobility as well as vascular integrity (by increasing torque and compression on the artery during flap rotation). This author routinely develops a pedicle base of 1.0 cm (Figure 8.3). Pedicle positioning should be contralateral to the predominant side of the wound to minimize pedicle twisting during movement. The right SA, for example, should be the PFF pedicle for a predominantly left-sided nasal defect.
Anesthesia
The PFF may be safely performed as an outpatient procedure. Tumescent anesthesia is useful by rapidly anesthetizing large areas with minimal patient discomfort. Local anesthesia (local infiltration and nerve blocks) may be supplemented by oral benzodiazepines (lorazepam, midazolam) and oral analgesics. Rarely, conscious sedation may be needed and are safely performed by dermasurgeons.5,6 Appropriate credentialing for advanced cardiac life support and sedation are essential for the latter modalities.
Execution
Cartilage and Lining Restoration
Cartilage grafts (CG) and nasal lining are essential ingredients for a stable nasal architecture. CG are either structural (native cartilage present but additional CG needed for support) (Figure 8.5) or restorative (replacing missing cartilage). Structural cartilage grafts serve to (1) support heavy flap tissue, (2) maintain airway patency of the internal nasal valve (priority in nasal reconstruction), (3) minimize scar contraction, and (4) restore contour projection (nasal tip). CG may be auricular (antihelix or concha; Figure 8.6), nasal (septum), or costal in nature. Auricular cartilage harvest is easiest and may be performed from an anterior or posterior approach. Anterior incisions are more accessible but scars are more visible than posterior incisions. Antihelical cartilage is excellent for long, straight segments whereas conchal cartilage is ideal for grafts that demand more curvature and substance.7,8 The subject of nasal lining is beyond the scope of this chapter. General options, however, for smaller mucosal defects (< 1 cm) include (1) turnover hinge flap, (2) turndown of a forehead flap extension, (3) full-thickness skin graft (FTSG), and (4) bipedicle vestibular skin advancement flap. Larger lining restoration may require (1) turnover forehead flap, (2) septal mucoperichondrial hinge flap, (3) composite septal chondromucosal pivotal flap, or (4) larger FTSG vascularized by an overlying PFF.9
Flap Harvesting and Pedicle Mobilization
The PFF may be mobilized at its superior edge to include just the skin and subcutis or down to underlying galea. The former approach facilitates flap debulking during inset but results in greater bleeding. A subcutaneous level is preferred if the flap is in hair-bearing scalp to expose terminal hair bulbs for depilation. The level of undermining, however, delves deeper into the subgaleal plane as one approaches the eyebrow to preserve the SA. The transition from subcutis to subgalea should occur at least 3 cm above the orbital rim. Undermining past the orbital rim should be under direct visualization as the SA is at risk of transection. Occasionally, subperiosteal release of the arcus marginalis and brow complex is required to enhance flap extension (Table 8.2). The PFF should now overlie the defect without tension (Figure 8.7).
Flap Preparation and Inset
Prior to any suturing, the flap thickness must be revised to fit the defect. Aggressive debulking except for a thin subdermal layer is possible because of the excellent vascularity of the SA (Figure 8.8). Constant reference to the defect is mandatory to prevent excessive thinning. Flap inset begins with interrupted epidermal sutures to secure its leading edge with the defect. If dermal-buried sutures are placed, this author prefers Poliglecaprone 25 (Monocryl, Ethicon) because of its minimal tissue reaction, a desirable feature on the sebaceous nasal tip.10 Dermal sutures contribute to flap security and minimize incision line separation. The proximal flap as it abuts the nasal dorsum is not sutured until pedicle division.
Donor Site Closure
Donor areas are approximated as much as possible and any remaining wound heals by second intention (Figure 8.9). Patients may be reassured that this open portion will be significantly smaller because of inevitable wound contraction (Figure 8.10). Tissue expansion and complex scalp flaps should be avoided as they often lead to excessive morbidity on both donor and recipient tissue without cosmetic benefits. At most, unilateral or bilateral W-plasties along the frontal hairline may be considered for complete closure of the forehead wound. These W-plasties act as bilateral advancement and rotation flaps, with the W design to camouflage incision scars and preserve hairline continuity.4 Broad scalp paresthesia may be a price of donor site closure.
Postoperative Care
Postoperative bleeding at the sides of the exposed pedicle is common and may be prevented with meticulous electrocoagulation and a Surgicel or Surgicel Nu-Knit wrap of the exposed pedicle. This oxidized cellulose gauze promotes hemostasis and its removal causes less discomfort than Vaseline gauze.11 Visual fields are blocked with pressure dressings and the wearing of glasses is usually not possible without preoperatively customized devices.