Published on 22/03/2015 by admin
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Last modified 22/03/2015
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Chapter 340 Pancreatic Function Tests
Steven L. Werlin
Pancreatic function can be measured by direct and indirect methods. An indirect test, the measurement of fecal elastase, which has become the standard screening test for pancreatic insufficiency, has a sensitivity and specificity >90%. Falsely abnormal results can occur in many enteropathies. The activity of other pancreatic enzymes in stool is now rarely measured.
Classically, a triple-lumen tube was used to isolate the pancreatic secretions in the duodenum. Measurement of bicarbonate concentration and enzyme activity (trypsin, chymotrypsin, lipase, and amylase
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