Oxygen and Medical Gas Therapy

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6 Oxygen and Medical Gas Therapy

Note 1: This book is written to cover every item listed as testable on the Entry Level Examination (ELE), Written Registry Examination (WRE), and Clinical Simulation Examination (CSE).

The listed code for each item is taken from the National Board for Respiratory Care (NBRC) Summary Content Outline for CRT (Certified Respiratory Therapist) and Written RRT (Registered Respiratory Therapist) Examinations (http://evolve.elsevier.com/Sills/resptherapist/). For example, if an item is testable on both the ELE and the WRE, it will simply be shown as: (Code: …). If an item is testable only on the ELE, it will be shown as: (ELE code: …). If an item is testable only on the WRE, it will be shown as: (WRE code: …).

Following each item’s code will be the difficulty level of the questions on that item on the ELE and the WRE. (See the Introduction for a full explanation of the three question difficulty levels.) Recall (R) level questions typically expect the exam taker to recall factual information. Application (Ap) level questions are harder because the exam taker may have to apply factual information to a clinical situation. Analysis (An) level questions are the most challenging because the exam taker may have to use critical thinking to evaluate patient data to make a clinical decision.

Note 2: A review of the most recent Entry Level Examinations (ELE) has revealed that an average of 12 questions (out of 140), or 9% of the exam, will cover oxygen and medical gas therapy. A review of the most recent Written Registry Examinations (WRE) has shown that an average of 7 questions (out of 100), or 7% of the exam, will cover oxygen and medical gas therapy. The Clinical Simulation Examination is comprehensive and may include everything that should be known by an advanced level respiratory therapist.

MODULE A

1. Oxygen administration

c. Administer oxygen to achieve adequate respiratory support (ELE code: IIID6) [Difficulty: ELE: R, Ap, An]

Oxygen (O2) must be administered in doses (up to 100%) that are adequate to treat hypoxemia, decrease the patient’s work of breathing, or decrease the work of the heart. Because the U.S. Food and Drug Administration has declared supplemental oxygen to be a drug, a physician’s order is required to give it to a patient or to make a change in the percentage. The only exceptions are when recognized protocols exist in your institution to give oxygen under certain limited conditions. For example, all patients with a diagnosed heart attack are given a nasal cannula at 2 L/min, or all patients undergoing cardiopulmonary resuscitation (CPR) receive 100% oxygen.

See Chapter 3 (Module A) for a listing of indications for drawing blood for an arterial blood gas (ABG) measurement. This list should be fairly complete for conditions that justify the need for supplemental oxygen. In general, the goal of giving supplemental oxygen is to keep the patient’s Pao2 level between 60 and 100 torr. Exceptions include carbon monoxide poisoning, severe anemia, and CPR, when the hope is to fully saturate the hemoglobin and increase the plasma oxygen content as much as possible. Oxygen should not be given without proof of hypoxemia or another clinical justification. When those conditions have been corrected, the oxygen percentage should be adjusted accordingly.

Giving supplemental oxygen is not done without risk. Following are oxygen-related problems that may be seen clinically.

2. Manipulate oxygen and specialty gas analyzers by order or protocol (Code: IIA26) [Difficulty: ELE: R, Ap; WRE: An]

c. Troubleshoot any problems with the equipment

Because so many different models are available, consult an equipment book or the manufacturer’s literature for details of the various analyzers. All portable, hand-held analyzers fall into one of the following categories: electric, physical/paramagnetic, and electrochemical.

3. Electrochemical analyzers: polarographic and galvanic fuel cell

Both polarographic and galvanic fuel cells make use of the fact that each oxygen molecule accepts up to two electrons and becomes chemically reduced. The more oxygen is in the gas sample, the more electrons are released from an oxidizing electrolyte solution. This is measured as an electrical current that is proportional to the oxygen percentage. These analyzers can monitor continuously and display the oxygen percentage. Both types are safe by themselves in the presence of flammable gases, but the added alarm systems are powered electrically and may make the units unsafe. Polarographic analyzers use a battery to polarize the gas sampling probe. Because of this, they have a faster response time than do the galvanic fuel cell types. Galvanic fuel cell analyzers do not need a battery for power. However, they usually include alarms that are battery powered.

Failure to calibrate either type can be caused by a weak battery, an exhausted supply of chemical reactant in the gas sampling probe, an electronic failure, or a damaged membrane over the probe. A damaged or torn probe will allow water, mucus, or blood onto the probe. The galvanic units must have their probes kept dry to be read accurately. Both types are pressure sensitive. High altitude causes them to display a lower-than-true oxygen percentage, and high pressure as seen in a ventilator circuit with positive end-expiratory pressure (PEEP) causes the units to display a higher-than-true oxygen percentage.

MODULE B

1. Manipulate oxygen and other gas cylinders, bulk storage systems, and manifolds, by order or protocol (ELE code: IIA9a) [Difficulty: ELE: R, Ap, An]

c. Troubleshoot any problems with the equipment

1. Oxygen and other gas cylinders

The different types of gases in cylinders are identified by the color code of the cylinder and the cylinder label. Note that only E cylinders have mandatory color coding. Color codings on the other cylinders are voluntary but usually are followed by the manufacturers. However, always read the label to be sure of the contents of the cylinder. The most important cylinder colors to remember are those of oxygen and air, but all are included in Table 6-1 for the sake of completeness.

TABLE 6-1 Color Codes for Gas Cylinders

Gas Color
Oxygen Green (white for international)
Air Yellow
Helium Brown
Helium and oxygen Brown and green (check the label for the percentage of each gas)
Carbon dioxide Gray
Carbon dioxide Gray and green (check the label for oxygen and the percentage of each gas)
Nitrous oxide Light blue
Cyclopropane Orange
Ethylene Red

2. Manipulate adjunct hardware, such as reducing valves, flowmeters, regulators, and high-pressure hose connectors, by order or protocol (ELE code: IIA9a) [Difficulty: R, Ap, An]

c. Troubleshoot any problems with the equipment

1. Reducing valves

Reducing valves are used to reduce the high pressure seen in a bulk oxygen storage system, manifold, or gas cylinder. One or more stages (pressure-reducing steps) can be used to reach the working pressure of 50 psig. Single-stage reducing valves reach the pressure in a single step. Multiple-stage reducing valves give finer control over pressure and flow by decreasing pressure in the first stage to about 200 psig and to 50 psig in the second stage. Occasionally, three stages are seen. All reducing valves (and regulators [combined reducing valve and flowmeter]) have the following built-in safety features:

image

Figure 6-1 Locations of the Pin Index Safety System holes in the cylinder valve face.

(Modified from Branson RD, Hess DR, Chatburn RL: Respiratory care equipment, ed 2, Philadelphia, 1999, Lippincott Williams & Wilkins.)

TABLE 6-3 Pin Index Safety System Gases and Pinhole Locations

Gas Pinhole Locations
Oxygen 2-5
Air 1-5
Oxygen/carbon dioxide (≤7%) 2-6
Oxygen/carbon dioxide (>7%) 1-6
Oxygen/helium (not >80% helium) 2-4
Oxygen/helium (helium >80%) 4-6
Nitrous oxide 3-5
Ethylene 1-3
Cyclopropane 3-6

It is necessary to “crack” or blow some gas out of a cylinder before putting any reducing valve or regulator onto the cylinder. Do this by attaching the tank wrench to the valve stem and slowly turning the valve stem in a counterclockwise (so-called “lefty-loosy”) direction to release some gas. This cracking is done to prevent any dust or debris from being forced into the reducing valve or regulator, which might cause a fire. See Figure 6-2 for a schematic drawing of an “E” tank of oxygen and how its yoke is connected. If the O-ring is missing or the yoke is misaligned on the post, a high-pressure gas leak will occur when the tank is opened with the tank wrench. Close off the tank to stop the leak by turning the tank wrench on the valve stem in a clockwise direction (so-called “righty-tighty”). Investigate the yoke-to-post connection to identify causes of the leak.

image

Figure 6-2 Details of an “E” size tank of oxygen and its yoke connector. A, A cross section through the stem (also called the control valve) of the tank shows its key features. B, A three-dimensional view shows how the yoke with its two pins aligns with the corresponding pin holes (locations 2 and 5) on the yoke. The plastic washer ensures a seal between the gas outlet on the stem and the yoke. (Not shown is the regulator that attaches to the yoke. See Figure 6-9.) C, A tank wrench that is attached to the valve stem (also called a control valve). Turn the wrench in a counterclockwise direction to open the tank and allow gas flow; close the tank to stop gas flow by turning the wrench in a clockwise direction.

(Redrawn from Sills JR: Respiratory care for the health care provider, Albany, 1998, Delmar Publishers.)

2. Flowmeters

Flowmeters are designed to regulate and indicate flow. They come with the following safety features so that they cannot be attached to the wrong reducing valve, regulator, high-pressure hose, or appliance:

Flowmeters usually are categorized by how they react to backpressure. To complicate matters further, we must remember that the three different manufactured types of flowmeters may or may not be backpressure compensated:

1. Non–backpressure-compensated (pressure-uncompensated) flowmeters will inaccurately indicate the flow through them in the face of backpressure. Figures 6-3 and 6-4 show non–backpressure-compensated kinetic and Thorpe types of flowmeters, respectively. Note that the Thorpe and kinetic flowmeters have the flow-control valve upstream from the meter. They read accurately if they are kept upright and do not have to “push” against any backpressure. If laid on their sides, the plunger and ball bearing do not indicate the set flow. They both read a lower flow than that actually delivered when faced with a backpressure.
2. The Bourdon flowmeter is designed similarly to the Bourdon gauge in the reducing valve (Figure 6-5). The face piece is marked in liters of flow rather than pressure. It is the flowmeter of choice in a transport situation because it may be laid flat with no effect to its flow if no backpressure is present. These flowmeters will display a higher flow than that actually delivered when faced with a backpressure.
3. Backpressure-compensated (pressure-compensated) flowmeters accurately indicate the flow through them in the face of backpressure. For this reason, they should be used whenever possible. Figures 6-6 and 6-7 show backpressure-compensated kinetic and Thorpe types of flowmeters, respectively. Note that both of these flowmeters have the flow-control valve downstream from the meter. Because of this, they read accurately in the face of backpressure as long as they are kept upright. Besides reading the label, this simple test enables the practitioner to tell whether a flowmeter is backpressure compensated:

image

Figure 6-3 Kinetic-type non–backpressure-compensated (pressure-uncompensated) flowmeter.

(Modified from McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-4 Thorpe-type non–backpressure-compensated (pressure-uncompensated) flowmeter.

(Modified from McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-5 Bourdon-type non–backpressure-compensated (pressure-uncompensated) flowmeter.

(From McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-6 Kinetic-type backpressure-compensated (pressure-compensated) flowmeter.

(Modified from McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-7 Thorpe-type backpressure-compensated (pressure-compensated) flowmeter.

(Modified from McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

d. Perform quality control procedures for flowmeters (Code: IIC6) [Difficulty: ELE: R, Ap; WRE: An]

When a quality control procedure for a flowmeter is performed, it is critical that a known flow be sent through it so that the flowmeter can be checked for accuracy. This should be done without any backpressure against the flowmeter. Review the previous discussion on troubleshooting flowmeters for the effects of backpressure on non–backpressure-compensated flowmeters and Bourdon flowmeters. Do not use any flowmeter that does not give an accurate reading.

3. Manipulate pulse-dose oxygen-conserving devices by order or protocol (ELE code: IIA9b) [Difficulty: R, Ap, An]

a. Get the necessary equipment for the procedure

Three types of intermittent-flow oxygen-conserving devices are available: pulse-dose oxygen delivery devices (PDODs), demand oxygen delivery systems (DODSs), and hybrid units. All are used in the home care setting and save money by delivering oxygen to the patient only during inspiration. These units take the place of a regulator and flowmeter that deliver a steady flow of oxygen to the patient.

The characteristics of each unit will vary depending on the manufacturer. However, the following main operational features are found:

Depending on the manufacturer, the unit can be used with oxygen tanks, a low-pressure liquid oxygen (LOX) system, or an oxygen concentrator. Be careful not to place a low-pressure unit on a high-pressure gas source because it will be damaged.

4. Manipulate air compressors by order or protocol (Code: IIA9f) [Difficulty: ELE: R, Ap; WRE: An]

c. Troubleshoot any problems with the equipment

Air compressors are used whenever a high-pressure gas source other than oxygen is needed. All three systems are alike in that they use an electrically powered motor, filter the room air as it enters and exits the compressor, and have a condenser to remove water vapor as it leaves the compressor. See Figure 6-11.

5. Manipulate air/oxygen proportioners (blenders) by order or protocol (ELE code: IIA9a) [Difficulty: ELE: R, Ap, An]

6. Manipulate oxygen concentrators (Code: IIA9c) [Difficulty: ELE: R, Ap; WRE: An] and portable oxygen concentrators (WRE code: IIA9e) [Difficulty: WRE: R, Ap, An] by order or protocol

a. Get the necessary equipment for the procedure

Two different types of oxygen concentrators (also known as oxygen enrichers) are available for the delivery of continuous low-flow oxygen in the home: molecular sieve and semipermeable plastic membrane.

c. Troubleshoot any problems with the equipment

The molecular sieve–type units deliver dry gas; therefore a humidification system is frequently added to the flowmeter. With the permeable plastic membrane–type units, the condensed water vapor must be emptied from the collection jar. In both types of oxygen concentrators, it is important to check the air-inlet filter on a monthly basis to keep it clean of dust and debris. Follow the manufacturer’s requirements regarding when filters should be replaced. The delivered oxygen concentration also should be checked each month. Follow the manufacturer’s guidelines for its preventative maintenance needs. The molecular sieve–type units must have the zeolite pellet canisters replaced on a scheduled basis.

Some units have a visual or audio alarm that warns when a problem occurs, such as power failure, low or high pressure, or low oxygen percentage. If the unit does not have a low oxygen percentage alarm, some home care practitioners have added an external analyzer with an alarm system. This alerts the patient to call the home care company to repair the equipment. If a patient says that he or she cannot feel any gas coming out of the cannula, have the patient place the prongs into a glass of water. If no bubbling is seen, have the patient check the tubing for any disconnections. If the concentrator is malfunctioning, have the patient turn it off and switch to oxygen from the backup oxygen cylinder until repairs can be made.

7. Manipulate portable liquid oxygen systems by order or protocol (WRE code: IIA9d) [Difficulty: WRE: R, Ap, An]

a. Get the necessary equipment for the procedure

A LOX system is used in the home when it is found to be more cost-effective than an oxygen concentrator or a battery of oxygen cylinders. An additional advantage is that the patient can carry a smaller portable unit in a shoulder bag for added mobility. Carrying it is less conspicuous than wheeling an E cylinder about. An early, widely known liquid oxygen system was the Linde Walker System (Union Carbide, Houston, TX). Figure 6-16 shows the key features of a large liquid oxygen reservoir that is kept in the patient’s home. Figure 6-17 shows its smaller portable companion, which can be filled from the large reservoir.

image

Figure 6-16 Drawing of the components of a home liquid oxygen supply unit.

(From Lampton LM: Home and outpatient oxygen therapy. In: Brashear RE, Rhodes ML, editors: Chronic obstructive lung disease, St Louis, 1978, Mosby.)

image

Figure 6-17 Drawing of the components of a portable liquid oxygen unit.

(From Lampton LM: Home and outpatient oxygen therapy. In: Brashear RE, Rhodes ML, editors: Chronic obstructive lung disease, St Louis, 1978, Mosby.)

8. Manipulate helium/oxygen equipment by order or protocol (WRE code: IIA15) [Difficulty: WRE: R, Ap, An]

a. Get the necessary equipment for the procedure

Helium/oxygen (He/O2 [heliox]) has been used historically in the management of patients with an upper airway obstruction. This may include tracheal tumor, postextubation laryngeal edema, and croup. More recently, heliox has been used with success in patients with status asthmaticus. The decreased density of a helium/oxygen mix compared with a nitrogen/oxygen mix reduces the patient’s work of breathing.

Various heliox gas mixtures come in high-pressure cylinders and require the use of an American Standard System reducing valve (or regulator) designed specifically for the gas or gas mix. As is shown in Table 6-3 and Figure 6-1, a reducing valve or regulator for an E cylinder must match the appropriate pinholes on the cylinder valve face. Corresponding high-pressure hoses also may be needed. Table 6-1 shows the color codes for the various gas cylinders. Pure helium comes in a brown cylinder, whereas helium and oxygen mixes come in brown and green cylinders. Always check the cylinder label for the exact percentage of the gases within it. Heliox comes in standard mixes of 80% He/20% O2, 70% He/30% O2, and 60% He/40% O2.

b. Put the equipment together and make sure that it works properly

The additional equipment needed depends on how the ordered heliox mixture is to be delivered to the patient.

1. Nonrebreather mask

In most clinical situations, a nonrebreather mask with reservoir bag is used to deliver heliox to a spontaneously breathing patient. A snugly fitting mask with one-way valves and a full reservoir bag will minimize breathing of any room air. (The next Module includes additional discussion on nonrebreather masks.) A helium flowmeter can be used to set the flow of heliox to the face mask. However, if a helium flowmeter is not available, an oxygen flowmeter can be added to the reducing valve on a heliox mix cylinder. In either case, set the gas flow high enough that the reservoir bag does not collapse on inspiration. The gas is humidified by attaching to the flowmeter a bubble humidifier with sterile water. Connect small-bore tubing between the humidifier nipple and the nonrebreather mask nipple.

If the patient is being treated for asthma, the nonrebreather mask can be modified to accept a small-volume nebulizer for bronchodilator medication delivery. (See Figure 6-18.) Care must be taken if the nebulizer is powered by the heliox mix, as shown. Some nebulizers will not operate normally. It may be necessary to increase the heliox flow by 50% to 100% from the usual rate of oxygen flow to get the unit to operate properly. Others simply choose to power the nebulizer with oxygen, as intended, for the treatment.

In the common situation where an oxygen flowmeter is being used, a calculation must be done to convert the flow seen on the oxygen flowmeter to the actual flow of heliox. This is necessary because helium is less dense than oxygen.

Exam Hint 6-6 (WRE)

Often one question requires the calculation of actual flow of a heliox mixture. The heliox factor must be known to do the calculation. One possible calculation involves figuring out the heliox flow from an observed flow through an oxygen flowmeter. The other possible calculation involves setting the observed flow through an oxygen flowmeter to achieve the desired heliox flow. See the following sample calculations.

The heliox factor must be used to determine the actual flow of heliox through an oxygen flowmeter, as follows:

  Helium/Oxygen Ratio Heliox Factor
1. 80% helium/20% oxygen 1.8
2. 70% helium/30% oxygen 1.6
3. 60% helium/40% oxygen 1.4

The following examples show how the actual heliox flow can be calculated from the observed oxygen flow seen on the flowmeter:

The following examples show how to set an oxygen flowmeter to deliver a needed heliox flow by dividing the desired flow by the heliox factor:

2. Mechanical ventilator

Delivering a helium/oxygen mix through a ventilator presents several technical challenges. First, select a ventilator that has been approved by the U.S. Food and Drug Administration (FDA) to deliver a heliox mix. In many ventilators, the decreased density of helium causes flow and volume sensors (usually a flow-type pneumotachometer) to read inaccurately. If a nonapproved ventilator needs to be used, it is recommended that pressure ventilation be used rather than volume ventilation. The risk with volume ventilation is the potential delivery of a larger tidal volume than that set on the ventilator. In addition, measure the patient’s exhaled tidal volume with a bellows-type spirometer rather than a pneumotachometer.

Connect the pure helium or heliox mix to the mechanical ventilator’s internal air/oxygen proportioner (blender) through the high-pressure air inlet. High-pressure oxygen will go through on its side of the unit, as usual. If pure helium is mixed with pure oxygen, dial the oxygen percentage, as needed, to adjust the mix of the two gases. For example, giving the patient 35% oxygen results in the patient’s also receiving 65% helium. However, if the patient is receiving a heliox mix (e.g., 70/30), more oxygen than is set on the blender will be delivered.

In any situation where a heliox mix is being used, the oxygen percentage must be measured. This is done to ascertain with certainty how much oxygen is being delivered and to ensure that the patient never receives less than 20% oxygen. Use a polarographic or galvanic fuel cell oxygen analyzer to monitor the patient’s oxygen percentage.

MODULE C

1. Manipulate oxygen hoods by order or protocol (ELE code: IIA12c) [Difficulty: ELE: R, Ap]

a. Get the necessary equipment for the procedure

Oxygen hoods are used to provide a warmed aerosol, humidity, and a controlled oxygen percentage to pediatric patients who weigh no more than 18 lb (8.2 kg). (See Figure 6-19.) Often the oxygen hood and the infant are placed inside of an incubator for better control of the environment and maintenance of body temperature. (See Chapter 8 for discussion on incubators.)

image

Figure 6-19 Infant in an oxygen hood.

(Courtesy Utah Medical Products Midvale, Utah.)

2. Manipulate oxygen tents by order or protocol (ELE code: IIA12b) [Difficulty: ELE: R, Ap]

3. Manipulate air entrainment devices and masks by order or protocol (ELE code: IIA1b) [Difficulty: ELE: R, Ap, An]

a. Get the necessary equipment for the procedure

Air entrainment masks are called high-flow devices because they are designed to provide the patient with a controlled oxygen percentage at a high enough flow rate to ensure that all of the patient’s inspiratory flow needs are met (Figure 6-21). To ensure that this happens, the total flow through the mask must be equal to or greater than the patient’s peak inspiratory flow. (The interested learner is encouraged to read about the Bernoulli principle, which regulates the mixing of fluids as the result of a decrease in pressure caused by a jet.) These masks are sometimes called Venturi masks, Venti masks, jet-mixing, and high airflow with oxygen enrichment (HAFOE) systems. See Table 6-5 for specific information on available air entrainment masks.

image

Figure 6-21 Adult wearing an air entrainment mask. A, High-velocity jet. B, An area of reduced lateral pressure (Bernoulli’s principle). C, Room air entrainment.

(From White GC: Basic clinical lab competencies for respiratory care, an integrated approach, Albany, NY, 1988, Delmar.)

These masks are recommended in any clinical situation in which a known, precise oxygen percentage must be given to the patient who has a variable respiratory rate, inspiratory/expiratory (I : E) ratio, tidal volume, or minute volume. Common situations include a patient with COPD and a patient in respiratory failure who needs increasing oxygen percentages.

b. Put the equipment together and make sure that it works properly

Depending on the manufacturer, the mask my come as a completed unit, may have air entrainment adapters to add to the mask, or may have an air entrainment adapter to adjust to set the desired oxygen percentage. See Table 6-5 for the recommended starting oxygen flow rate for the different oxygen percentage masks. Because it is difficult to ensure that the patient’s peak inspiratory flow is matched by the gas flow through the mask, the following guidelines are recommended:

Exam Hint 6-8 (ELE)

It has been necessary on past exams to calculate the needed change in the oxygen flow to increase the total gas flow to meet or exceed a patient’s peak inspiratory flow. This ensures that the proper oxygen percentage is delivered.

Some patients may complain that the gas coming through the mask is dry. To resolve this problem, some manufacturers have designed an aerosol adapter to add at the jet. A separate bland aerosol then is added to the room air (21% oxygen that enters the jet stream). Make sure that the adapter fits properly and does not interfere with or block the jet or room air entrainment ports. Do not add a bubble-type humidifier to the jet on the mask because the high backpressure through the jet will cause the pressure relief (pop-off) valve to open, and the oxygen will leak out.

c. Troubleshoot any problems with the equipment

The two different types of air entrainment devices are based on the physical principles seen in the Bernoulli effect. It is important to know about the two different types to understand what can go wrong with them and how they can be fixed. Make sure that the correct liter flow of oxygen, jet size, and air entrainment port setting are selected to get the desired total flow and oxygen percentage.

4. Manipulate a low-flow nasal cannula by order or protocol (ELE code: IIA1a) [Difficulty: ELE: R, Ap, An]

a. Get the necessary equipment for the procedure

The traditional nasal cannula is a low-flow oxygen delivery tube that has been modified with two short prongs to deliver oxygen to the nostrils (Figure 6-22). Nasal cannulas come in neonatal, pediatric, and adult sizes based on the diameter of the prongs. Care must be taken to make sure that the patient’s nares are patent and are not plugged by a common cold, a deviated septum, or another unseen problem. This simple oxygen delivery device is used very widely because it is more comfortable for many patients than an air entrainment mask or other types of face masks. Current clinical practice guidelines indicate that, in an adult, an oxygen flow of 4 L/min or less does not require additional humidification if the patient has a normal upper airway.

image

Figure 6-22 Adult wearing a nasal cannula.

(From Wilkins RL, Stoller JK, Kacmarek RM, editors: Egan’s fundamentals of respiratory care, ed 9, St Louis, 2009, Mosby.)

b. Put the equipment together and make sure that it works properly

If an adult is getting from 1 to 4 L/min of oxygen and complains of nasal dryness, or if a higher flow is given, humidification will have to be provided. Often this is a bubble-type humidifier, as discussed in Chapter 8. Make sure that it is properly filled with sterile water and that the oxygen bubbles through it. Check the high-pressure pop-off valve for pressure release and a whistling sound. Before placing the cannula on the patient, check to see that the oxygen is flowing through the tubing. If available, use a cannula with curved prongs. They direct the gas flow toward the back of the nasal passages for better natural humidification and are better for patient comfort. Take care to avoid pulling the elastic restraining band too tightly around the head. Some brands loop the oxygen tubing over the ears to be drawn up snugly under the chin. Often this type is more comfortable than the types that have an elastic band.

The problem with a nasal cannula is that the delivered oxygen percentage is unreliable. Variations in the patient’s respiratory rate, I : E ratio, tidal volume, and minute volume result in different inhaled oxygen percentages. This is clearly unacceptable in an unstable patient in whom Pao2 values are being used to help judge the changing cardiopulmonary status. Because of this clinical limitation, this device and the other low-flow oxygen delivery systems in the discussions that follow should be used only with stable patients. In the adult, the delivered oxygen percentage can be estimated at approximately 4% for each liter of oxygen per minute (Table 6-6). Flows usually are limited to 6 L/min to avoid excessive irritation to the nasal passages. Flows usually are limited to no more than 1 to 2 L/min in infants and 4 L/min in older children. The pulse oximetry value or Pao2 level should be checked in patients of any age whenever a flow change is made or when the patient’s condition changes significantly.

TABLE 6-6 Estimated Delivered Oxygen Percentage in Adults Based on the Oxygen Liter Flow Through a Nasal Cannula

Oxygen, L/min Estimated Delivered Oxygen, %
1 24
2 28
3 32
4 36
5 40
6 44

5. Manipulate an oxygen-conserving nasal cannula by order or protocol (ELE code: IIA9b) [Difficulty: ELE: R, Ap, An]

b. Put the equipment together and make sure that it works properly

At least two different types of oxygen-conserving cannulas are found. Figure 6-23 shows a reservoir nasal cannula and how it operates. It has an 18-mL reservoir that fills when the patient exhales and gives up its oxygen bolus during the next inspiration. Figure 6-24 shows a pendant nasal cannula with its reservoir that hangs on the chest.

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Figure 6-24 Drawing of a patient wearing a pendant reservoir nasal cannula made by CHAD Therapeutics (Chatsworth, CA).

(From Wilkins RL, Stoller JK, Kacmarek RM, editors: Egan’s fundamentals of respiratory care, ed 9, St Louis, 2009, Mosby.)

6. Manipulate a high-flow nasal cannula by order or protocol (ELE code: IIA1c) [Difficulty: ELE: R, Ap, An]

a. Get the necessary equipment for the procedure

A high-flow nasal cannula (HFNC) is designed to provide warmed and humidified oxygen at a high enough flow rate to fully meet the patient’s peak inspiratory flow needs. This type of nasal cannula is better tolerated by many severely hypoxic patients than a nonrebreather mask because it provides 100% relative humidity at body temperature (BTPS [body temperature, pressure, saturated gas] conditions), and there is no drying of the nasal mucosa. For these reasons, the HFNC has found a growing clinical application in adult and neonatal populations. Adults with congestive heart failure and pulmonary edema may be kept off of continuous positive airway pressure (CPAP) or mechanical ventilation through the use of an HFNC.

Early evidence indicates that an HFNC may be used with some premature neonates as an alternative to CPAP or mechanical ventilation. Evidence suggests that neonatal patients receiving HFNC have a positive mouth pressure of about 3 to 4 cm water, which corresponds to a similar CPAP level. However, this pressure is maintained only when the mouth is closed. There is also the risk that an HFNC will create a higher CPAP level than desired. So, the smallest possible nasal cannula should be used to allow for a leak.

Although future research will indicate the best patient populations and application methods for HFNC, currently three systems are available: Vapotherm 2000i (Vapotherm, Stevensville, MD), the Salter Labs (Arvin, CA) high-flow cannula and humidifier, and the AquinOx High Flow Humidification System (Smiths Medical ASD Inc., Kent, UK). The Vapotherm 2000i will be used in the following discussion.

b. Put the equipment together and make sure that it works properly

Figure 6-25 shows a Vapotherm 2000i that is opened to show the vapor transfer cartridge. Water is continuously supplied into the unit and is warmed before entering the cartridge to be vaporized to humidify the patient’s oxygen. The temperature can be adjusted but usually is kept at body temperature. A pediatric cartridge will be used for a flow of 1 to 8 L/min. An adult cartridge will be used for flows of 5 to 40 L/min. An oxygen hose is attached at the bottom of the unit and then is attached to the patient’s nasal cannula. It is possible to attach the patient’s nasal catheter (rarely used clinically anymore) or transtracheal oxygen catheter. The flow of oxygen is adjusted to meet the patient’s clinical goal for oxygenation. The higher the oxygen flow, the higher the delivered oxygen percentage—possibly up to 100% oxygen.

7. Manipulate oxygen masks: simple oxygen mask, partial-rebreathing mask, nonrebreathing mask, and face tent, by order or protocol (ELE code: IIA1a) [Difficulty: ELE: R, Ap, An]

c. Troubleshoot any problems with the equipment

1. Simple oxygen mask

This mask, like all others, is designed to fit over the patient’s nose and mouth and act as an oxygen reservoir for the next breath (Figures 6-26 and 6-27). Various adult and pediatric sizes are available, and the patient should wear one that best fits the facial contours and size of the face. This is recommended for comfort, as well as to try to increase the inspired oxygen percentage by decreasing the amount of room air that is inspired. However, because a simple oxygen mask does not provide all of the patient’s tidal volume gas, it is classified as a low-flow device. Exhaled breath escapes through the exhalation ports. The patient’s breathing pattern affects the amount of room air that is breathed in through the same exhalation ports. These ports also are important in case the oxygen flow to the mask is cut off.

image

Figure 6-26 Close-up view of a simple oxygen mask.

(From McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-27 Child wearing a simple oxygen mask.

(From Gaebler G, Blodgett D: Gas administration. In Blodgett D, editor: Manual of pediatric respiratory care procedures, Philadelphia, 1982, Lippincott.)

Because the oxygen reservoir in the mask is not large enough to meet the patient’s tidal volume, the inspired oxygen percentage is unpredictable. Oxygen flows between 5 and 10 L/min should provide approximately 35% to 60% inspired oxygen. The pulse oximetry value or Pao2 level should be checked whenever a flow change is made, or when the patient’s condition changes significantly.

A bubble humidifier is often added so that the gas is not dry. Make sure that it works properly and that oxygen is flowing through the tubing before putting it on the patient. This and all other masks use an adjustable elastic strap that goes behind the head to hold it in place. Make sure that the mask fits snugly but not so tight as to cut off circulation.

2. Partial-rebreathing mask

The partial-rebreathing mask has a 500- to 1000-mL plastic bag added to the mask to act as an oxygen reservoir for the next breath (Figures 6-28, 6-29, and 6-30). Child- and adult-size masks are commonly available. When properly applied, the first third of the patient’s exhaled gas from the anatomic dead space is exhaled back into this bag. This gas is close to pure oxygen and has no carbon dioxide. Exhaled breath escapes through the exhalation ports. The patient’s breathing pattern affects the amount of room air that is breathed in through the same exhalation ports. Because of this room air entrainment, a partial-rebreathing mask is classified as a low-flow device. These ports also are important in case the oxygen flow to the mask is cut off; the patient will breathe in room air. The added reservoir of oxygen results in a higher percentage being given to the patient than with a simple oxygen mask. In all cases, set an oxygen flow high enough that the reservoir bag does not collapse by more than one-third on inspiration. For example, an initial oxygen flow of between 6 and 10 L/min should provide approximately 35% to 80% inspired oxygen.

image

Figure 6-28 Outside view of a partial-rebreathing mask.

(From McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-29 Cutaway view of a partial-rebreathing mask showing gas flow.

(From Thalken FR: Medical gas therapy. In: Scanlan CL, Spearman CB, Sheldon RL, editors: Egan’s fundamentals of respiratory care, ed 5, St Louis, 1990, Mosby.)

image

Figure 6-30 Child wearing a partial-rebreathing mask.

(From Gaebler G, Blodgett D: Gas administration. In Blodgett D, editor: Manual of pediatric respiratory care procedures, Philadelphia, 1982, Lippincott.)

A bubble humidifier often is added so that the gas is not dry. Make sure that it works properly, that the oxygen is flowing through the tubing, and that the reservoir bag has been filled before putting it on the patient. Adjust the flow as needed to ensure that the reservoir does not collapse by more than one-third on inspiration. This ensures that the mask and the reservoir are filled with as much oxygen as possible. A pulse oximetry value or Pao2 level should be checked whenever a flow change is made, or when the patient’s condition changes significantly.

3. Nonrebreathing mask

The nonrebreathing mask initially looks like the partial-rebreathing mask with its plastic bag added as an oxygen reservoir for the next breath (Figures 6-31 and 6-32). However, it should be noted that a one-way valve has been added between the mask and the reservoir bag. This allows the bag to be filled with pure oxygen that is available for the next breath. No exhaled gas can enter the reservoir. Two (sometimes one) one-way valves are added to the exhalation ports on the mask. In theory, with a tight-fitting mask and a high enough oxygen flow, the patient breathes in only oxygen from the mask and reservoir and no room air. However, because of leaks between the mask and the patient’s face, the nonrebreathing mask is classified as a low-flow device. Exhaled breath escapes through the exhalation ports as with the partial-rebreathing mask. Not shown is an emergency pop-in valve that allows room air to be drawn into the mask if the oxygen supply is cut off. Adult and pediatric sizes are available. The mask should be conformed to fit the patient’s facial contours and size as much as possible. As mentioned earlier, this is for comfort and to try to increase the inspired oxygen percentage by decreasing the amount of room air that is inspired. In theory, it is possible to deliver 100% oxygen with this mask if the oxygen flow is high enough and the mask is airtight over the face. However, experience has shown that the disposable masks that are usually available in the hospital do not prevent room air from being drawn in. In all cases, set an oxygen flow high enough that the reservoir bag does not collapse by more than one-third on inspiration. For example, an initial oxygen flow between 8 and 10 L/min should provide approximately 60% to 80% (or more) inspired oxygen.

image

Figure 6-31 Outside view of a nonrebreathing mask.

(From McPherson SP: Respiratory care equipment, ed 4, St Louis, 1990, Mosby.)

image

Figure 6-32 Cutaway view of a nonrebreathing mask showing gas flow.

(From Thalken FR: Medical gas therapy. In: Scanlan CL, Spearman CB, Sheldon RL, editors: Egan’s fundamentals of respiratory care, ed 5, St Louis, 1990, Mosby.)

A bubble humidifier often is added so that the gas is not dry. Make sure that it works properly, that the oxygen is flowing through the tubing, and that the reservoir bag has been filled before putting it on the patient. Adjust the flow as needed to ensure that the reservoir does not collapse by more than one-third on inspiration. This ensures that the mask and the reservoir are filled with oxygen, and that the patient’s tidal volume comes completely from the reservoir bag. Try to make the mask fit as closely as possible to minimize room air entrainment. The patient’s pulse oximetry value or Pao2 level should be checked whenever a flow change is made, or when the patient’s condition changes significantly.

8. Manipulate a transtracheal oxygen catheter by order or protocol (ELE code: IIA1a) [Difficulty: ELE: R, Ap, An]

9. Manipulate tracheostomy appliances: mask/collar and Brigg’s adapter/T-piece, by order or protocol (ELE code: IIA1a) [Difficulty: ELE: R, Ap, An]

c. Troubleshoot any problems with the equipment

2. Brigg’s adapter/T-piece

The Brigg’s adapter or T-piece is designed to provide air or supplemental oxygen and aerosol to an endotracheal or tracheostomy tube. It has one 15-mm inner diameter (ID) opening that fits over any endotracheal or tracheostomy tube adapter. The other two openings are 22 mm outer diameter (OD) so that aerosol tubing can be added (Figure 6-36). A nebulizer is commonly used for humidity because the patient’s upper airway is bypassed. Make sure that the nebulizer is filled with sterile water; if there is a high-pressure pop-off valve, make sure it is working and that adequate mist is flowing through to the adapter before putting it on the patient. The nebulizer is usually an air entrainment type of device, so the oxygen percentage can be adjusted.

A length of aerosol tubing added downstream from the adapter acts as a reservoir so that the inspired oxygen percentage is ensured. A reservoir of 50 to 100 mL of aerosol tubing is commonly needed for the adult. Care must be taken to adjust the gas flow so that it is high enough to meet the patient’s peak inspiratory flow rate. This can be determined by watching the aerosol flow past the adapter and reservoir. Make sure that during inspiration the aerosol is still flowing past the tracheostomy or endotracheal tube and into the reservoir. Inadequate flow could cause the patient to rebreathe gas from the reservoir. This gas has just been exhaled and is high in carbon dioxide and low in oxygen.

MODULE D

2. Adjust the flow or gas concentration (Code: IIIF2e2) [Difficulty: R, Ap; WRE: An]

The indications for all of the specialty gases are listed in Box 6-1. Although none of these gases is used widely in respiratory care, all can be very beneficial when indicated.

b. Nitric oxide therapy

Because nitric oxide (NO) is a pulmonary vasodilator, it has been shown to be effective in the treatment of newborns with pulmonary hypertension (persistent pulmonary hypertension of the newborn [PPHN]). The FDA has approved the use of INOmax (0.8% nitric oxide and 99.2% nitrogen) to deliver inhaled nitric oxide to these patients. The currently recommended dosing range of inhaled NO to treat PPHN is 5 to 15 parts per million (ppm). The possible range for delivered NO is 2 to 80 ppm. Be prepared to increase the level of NO as needed, to reverse the pulmonary hypertension. When the patient improves, the NO level will need to be decreased. This usually is done by cutting the NO level in half, assessing the patient, and cutting the NO level in half again, etc., as tolerated.

To deliver the needed concentrations of nitric oxide and supplemental oxygen, the INOvent delivery system is needed. It is used to set the desired mix of INOmax to the newborn’s ventilator and to monitor the levels of NO, nitrogen dioxide (NO2), and oxygen delivered. Because NO is chemically changed in the body to toxic NO2 and nitric acid, it is important to closely monitor the level of nitrogen dioxide. Low levels of NO2 can cause a pneumonitis, and higher levels can cause pulmonary edema. The patient’s methemoglobin level also should be monitored, as NO can cause an elevated level. Be prepared to decrease the level of NO to reduce the level of toxic NO2.

Inhaled NO has not been approved for adult patients. However, some reports of nitric oxide administered to patients with pulmonary hypertension and acute respiratory distress syndrome (ARDS) show promising results.

c. O2/CO2 (carbogen) therapy

Carbon dioxide is available in tanks of pure CO2 or a mix of 5%:95% or 10%:90% (carbon dioxide : oxygen ratio). Carbogen is used during cardiopulmonary bypass procedures to maintain the patient’s PaCO2. Common clinical uses are listed in Box 6-1. Because inhaling carbon dioxide runs counter to a person’s normal exhalation of CO2, the patient’s PaCO2 can increase with resulting respiratory acidosis. So, the patient’s arterial blood gas values, vital signs, and mental status must be monitored closely. Be prepared to decrease the carbogen percentage or stop the breathing of carbogen if the patient shows any adverse signs or symptoms.

A child with hypoplastic left-heart syndrome (HLHS) usually is being mechanically ventilated. The infant with this congenital heart defect must maintain an open foramen ovale and patent ductus arteriosus (PDA) for adequate systemic circulation (a right-to-left intracardiac shunt). Carbogen is added by small-bore tubing connecting the gas cylinder with a T-piece connected into the ventilator circuit. Usually enough carbogen flow is added to result in measurement of 1% to 4% carbon dioxide on a capnometer. Because increased carbon dioxide is a pulmonary vasoconstrictor, the PDA can be maintained. The infant’s vital signs and ABG values must be closely monitored to guide the adjustment in carbogen.

The carbon dioxide response curve test is a measurement of the increase in minute volume caused by breathing different concentrations of carbon dioxide when the patient’s oxygen level is normal. This pulmonary function test is performed on patients with COPD to determine whether their breathing will increase when their carbon dioxide level is increased. Depending on the method of test performed, the patient inhales between 1% and 7% carbon dioxide. The flow and concentration must be adjusted to maintain the desired carbon dioxide level as measured on a capnometer. An oxygen analyzer also should be included in the system to make sure that the patient does not inhale less than 21% oxygen.

The treatment of hiccups usually requires only that the patient rebreathe from a paper bag. If necessary, a small amount of carbon dioxide can be added to stop the hiccups.

MODULE E

MODULE F

3. Monitor the outcomes of respiratory care protocols (Code: IIIH7b) [Difficulty: ELE: R, Ap; WRE: An]

Look for signs of hypoxemia and be prepared to recommend a change in the patient’s oxygen delivery system or oxygen percentage to correct the problem. Tachycardia and tachypnea are common findings in hypoxemic patients. Proper oxygen therapy should relieve the problem so that the patient’s vital signs return toward normal. An abnormal heart rhythm caused by hypoxemia should return to normal with relief of the problem. Check the patient’s pulse oximetry or Pao2 value whenever a change in the inspired oxygen percentage or a significant change in the patient’s clinical condition occurs.

c. Independently change the mode of administering the oxygen (ELE code: IIIF2d1) [Difficulty: R, Ap, An]

Every patient’s oxygen percentage or flow must be tailored to meet the patient’s clinical goals. Usually this means keeping patients who are acutely hypoxemic at a Pao2 level between 60 and 100 torr and an Spo2 value between 90% and 97%. Exceptions, when the blood oxygen level is kept as high as possible, include cardiopulmonary resuscitation and treatment for carbon monoxide poisoning. Another exception is the patient with COPD who is hypoxemic and hypercarbic. Usually these patients’ conditions are maintained with a moderate hypoxemia. The Pao2 level should be between 50 and 60 torr and the Spo2 value between 85% and 90%. It is imperative to keep the oxygen in this relatively narrow range. Further hypoxemia will result in pulmonary hypertension and cor pulmonale. Cardiac dysrhythmias or arrest and death can occur if the hypoxemia is severe (<40 torr). Oxygen levels in the normal range (>60 torr) may result in blunting of the hypoxic drive. This can result in bradypnea and even greater carbon dioxide retention with corresponding acidemia. When the carbon dioxide pressure (PaCO2) level exceeds 80 to 90 torr, many patients become drowsy or somnolent. The goal of treatment is to decrease the Fio2 to reduce the Pao2 level to 50 to 60 torr. This, in turn, stimulates the hypoxic drive so that the patient increases his or her ventilation. See Chapter 3 for a complete discussion of the interpretation of arterial blood gas values.

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SELF-STUDY QUESTIONS FOR THE ENTRY LEVEL EXAM See page 587 for answers

SELF-STUDY QUESTIONS FOR THE WRITTEN REGISTRY EXAM See page 612 for answers