Outcome statistics

Published on 03/06/2015 by admin

Filed under Neonatal - Perinatal Medicine

Last modified 22/04/2025

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CHAPTER 32 Outcome statistics

Mark Davies

The following statistics for survival and morbidity relate to outcomes of interest at the time of hospital discharge.

The outcomes shown are for babies born at the Royal Brisbane and Women’s Hospital (RBWH), from 2000 to 2005 inclusive. These data, while specific for the RBWH, will give ball-park numbers that will be of some use when counselling parents.

Survival

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Figure 32.1 Survival statistics.

Morbidity

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Figure 32.2 Duration of total hospital stay in babies surviving to discharge

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Figure 32.3 Proportion of babies admitted who had respiratory support

CPAP = continuous positive airway pressure

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Figure 32.4 Duration of mechanical ventilation for all admissions

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Figure 32.5 Proportion of survivors who went home on oxygen therapy

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Figure 32.6 Proportion of all admissions who had intraventricular haemorrhage (IVH)

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Figure 32.7 Proportion of all survivors who had periventricular leucomalacia (PVL)

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Figure 32.8 Proportion of all survivors who had severe retinopathy of prematurity (ROP)

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Figure 32.9 Proportion of all survivors with major neonatal morbidity

Major neonatal morbidity = oxygen at 36 weeks, or definite necrotising enterocolitis (NEC), or retinopathy of prematurity (ROP) stage 3 or 4, or intraventricular haemorrhage (IVH) grade 3 or 4, or periventricular leukomalacia (PVL), or porencephalic cyst, or hydrocephalus

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Figure 32.10 Proportion of all survivors with major neonatal neurosensory morbidity

Major neonatal neurosensory morbidity = retinopathy of prematurity (ROP) stage ≥3, or intraventricular haemorrhage (IVH) grade 3 or 4, or periventricular leukomalacia (PVL), or porencephalic cyst, or hydrocephalus

Long-term outcome

Preterm infants are at risk for adverse neurodevelopmental outcome. This may include non-specific developmental delay, cerebral palsy (CP), intellectual deficit, deafness and blindness.

The following data are derived from combining the data from a few recent studies and follow-up data from the RBWH. They are a rough guide only: the confidence intervals around them are wide. The following definitions for the levels of disability are an example of those used:

• moderate disability — Developmental Quotient between 2 and 3 standard deviations below the mean; deaf; moderate CP (walks with aids)
• severe disability — Developmental Quotient more than 3 standard deviations below the mean; blind; severe CP (unable to walk).

Gestational age (weeks) % moderate/severe disability
23 ∼55
24 ∼35
25 ∼30
26 ∼25
27 ∼20
28 ∼15
29 <10
30 <10
31 <5
32 <5
33 <5

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