Neoplasms of the Liver

Published on 22/03/2015 by admin

Filed under Pediatrics

Last modified 22/03/2015

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Chapter 498 Neoplasms of the Liver

Hepatic tumors are rare in children. Primary tumors of the liver account for approximately 1% of malignancies in children, with an annual incidence of 1.6 cases per million children in the USA. Between 50-60% of hepatic tumors in children are malignant, with >65% of these malignancies being hepatoblastomas and most of the remainder, hepatocellular carcinomas. Rare hepatic malignancies include embryonal sarcoma, angiosarcoma, malignant germ cell tumor, rhabdomyosarcoma of the liver, and undifferentiated sarcoma. More common childhood malignancies such as neuroblastoma and lymphoma can metastasize to the liver. Benign liver tumors, which usually present in the first 6 mo of life, include hemangiomas, hamartomas, and hemangioendotheliomas.