Intramural (Mesenchymal) Intestinal Tumors

Published on 13/07/2015 by admin

Filed under Radiology

Last modified 22/04/2025

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 Most commonly diagnosed benign small bowel (SB) tumor (easy to recognize on CT)

image Most common cause of SB intussusception (symptomatic)
• GI stromal tumor (GIST)

image Most common type (if duodenum is included)
image Often large, exophytic, with central necrosis, may communicate with lumen
• Leiomyoma

image Calcifications and necrosis are common (in this rare tumor)
• Hemangioma

image Usually small, ± calcified phleboliths
• Neural tumors

image Schwannoma, paraganglioma, neurofibroma
image Multiple SB neurofibromas may be seen in neurofibromatosis type 1 (NF1)

TOP DIFFERENTIAL DIAGNOSES

• Intestinal metastases and lymphoma
• Small bowel carcinoma
• Intramural hematoma
• Ectopic pancreas

CLINICAL ISSUES

• Asymptomatic (most common)
• GI bleeding, intestinal obstruction, intussusception

DIAGNOSTIC CHECKLIST

• Small bowel follow-through: Very low yield procedure to identify small bowel tumors

image CT enterography is best imaging test
image Capsule endoscopy or double balloon endoscopy may miss submucosal masses
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(Left) CT shows a fat-density mass image diagnostic of a lipoma. The mass appears to be intraluminal, due to the effects of chronic peristaltic tugging on the mass, causing it to elongate into an intraluminal polypoid shape.

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(Right) Axial CECT shows a well-circumscribed mass image with heterogeneous enhancement in the pelvis, intimately associated with the adjacent small bowel. This proved to be a leiomyoma of the bowel with necrosis accounting for the heterogeneity.
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(Left) A coronal CT section shows a homogeneous, soft tissue density mass image within the wall of the duodenum without luminal obstruction. The homogeneous soft tissue density supports the diagnosis of leiomyoma and excludes lipoma, but other masses, such as GI stromal or neural tumors, could have a similar appearance.

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(Right) Axial CET shows a cylindrical mass image within the lumen of the 3rd portion of duodenum, without signs of bowel obstruction. This was a paraganglioma arising from the duodenal wall.
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Upper GI series shows a large duodenal mass with central ulceration image in this patient with a gastrointestinal stromal tumor.

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Axial CECT shows a large mass in the medial wall of the duodenum with a large central ulceration image in this patient with a gastrointestinal stromal tumor.
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Axial CECT shows a duodenal teratoma image that is comprised of fat, calcification, and soft tissue.
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Axial CECT shows a fat-density intramural/luminal mass image in this patient with jejunal lipoma.