Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases: Part 2

Published on 04/03/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 04/03/2015

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Chapter 22 Infectious Mononucleosis and Other Epstein-Barr Virus–Associated Diseases

Part 2

Carl Allen, Cliona M. Rooney, Stephen Gottschalk

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Figure 22-1 EBV-LATENT GENE EXPRESSION AND IMMUNOGENICITY OF COMMON EBV-ASSOCIATED MALIGNANCIES.

EBNA, Epstein-Barr nuclear antigen; LP, leader protein. For an explanation of symbols, see Fig. 21-1. *Not all lymphomas are latency type III.

EBV-Associated Malignancies

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Malignancy EBV Frequency
Hodgkin disease ≈40%
Non-Hodgkin lymphomas  
Burkitt lymphoma 20%-95%
Diffuse large B-cell lymphoma and CD30+ Ki-1+ anaplastic large cell lymphoma 10%-35%

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