Imaging and interventional techniques in surgery
Plain radiology
Some foreign bodies in wounds are radiopaque, including metal and most glass fragments, but wood and plastic are radiolucent and invisible. Gauze swabs used in operating theatres are radiolucent but have a radiopaque strand allowing them to be located radiographically if left in a wound (Fig. 5.1).
Personal radiation protection
• Giving training in radiation protection to all staff using and working near X-ray equipment
• Ensuring every investigation helps with management and none is performed merely as ‘routine’
• Improving design of X-ray equipment to minimise radiation dose whilst preserving diagnostic detail. X-ray scatter is minimised and unwanted types of radiation removed by filters
• Physical barriers are built into radiology suites or provided to protect staff. These include barium plaster in walls, lead-glass windows and lead-rubber aprons
• Workers involved in X-rays should keep away from the direct beam line and maintain a good distance from the X-ray source during exposure. Note the inverse square law determines the fall-off of radiation with distance
• All involved in radiography should wear X-ray-sensitive film badges which need to be regularly monitored for excess radiation
General Principles of Radiology
These factors are involved in producing a useful radiographic image:
• X-ray power and exposure time—chosen to give a diagnostically useful exposure without excess dosage. Good quality images have a range of densities appropriate to the anatomical area. For example, thoracic spine views require a larger dose than lungs
• Different projections (views) produce different views of the same subject. The X-ray tube is effectively a point source with a diverging beam (see Fig. 5.2), so the subject is magnified. The distortion least affects the body part closest to the film, which is thus shown most clearly. The beam direction should be recorded on the film as it has consequences for interpretation, e.g. a frontal chest film might be PA (postero-anterior) or AP (antero-posterior). With lateral exposures, the side nearest the film is indicated, e.g. a ‘Rt’ lateral chest X-ray (CXR) has the right side nearest the film
• Patient position during exposure (i.e. supine, prone, oblique or erect) affects the image because of gravity affecting organs, gas or fluid. Most films are taken with the patient lying supine with the X-ray beam aimed vertically downwards. A horizontal beam can demonstrate fluid levels in a cavity or bowel (lateral decubitus), or free gas under the diaphragm
Electronic recording techniques
• Substantial cost saving on film and processing chemicals
• Reduced physical space needed for storage
• Reduced staff costs—no need to file or retrieve films
• Better availability of images—no need to obtain physical films; several viewers can see the same images simultaneously in their place of work
• Substantially reduced numbers of missing examinations
• Easy transmission of images from one institution to another—by portable storage media (CD-ROM) or electronic links
‘Filmless’ X-ray departments are becoming the norm, with images displayed on terminals dispersed around the hospital. Images can be accessed remotely by family practitioners and clinicians at home or in other hospitals.
Plain radiology
Chest X-ray: Interpreting plain chest X-rays requires a methodical approach. Several learned documents have been written on the subject (see e.g. http://student.bmj.com/student/view-article.html?id=sbmj04018), and no attempt will be made to produce an incomplete version here.
Plain abdominal radiology: Most abdominal films are taken with the patient supine. Bowel is visible when it contains gas (Figs 5.3 and 5.4); normal small bowel is less than 3 cm wide and tends to occupy the centre of the abdomen. When dilated, it shows transverse folds (plicae circulares) which completely cross the lumen. The colon usually lies peripherally and has haustrations; these folds only partly traverse the lumen (Fig. 5.3). Normal colon is less than 6 cm wide and often contains faecal lumps with a mottled appearance. Further reading about this topic is available from: http://www.studentbmj.com/topics/clinical/imaging_techniques.php.
When examining an abdominal X-ray, important features to look for are:
• Calcification in areas prone to stone formation, e.g. kidney, ureters, bladder or biliary tree (see below, Urography, Fig. 5.8a)
• Dilated bowel (stomach, small or large bowel)
• Free intraperitoneal gas indicating bowel perforation
• Gas in abnormal places (e.g. biliary tree or urinary tract) suggesting a fistula with bowel
• Non-biological objects, e.g. foreign bodies, surgical tubes or pieces of metal
• Pathological calcification, e.g. aortic aneurysm, pancreas, adrenals or uterine fibroids
The limitations of plain abdominal radiography are summarised in Box 5.1.
Free intraperitoneal gas: Free gas is diagnostic of bowel perforation except after recent laparotomy. A horizontal beam chest or upper abdominal X-ray with the patient erect is the most useful method of demonstrating it as a radiolucent layer beneath the diaphragm (see Fig. 19.8, p. 275). The layer can be very small but is often obvious. Perforation can also be confidently diagnosed when the inside and outside of the bowel wall are both outlined by radiolucent shadows, but this is rare (Rigler’s sign, Fig. 32.7, p. 413). Where the result is doubtful or the patient too ill to sit or stand, he or she should be placed in the right-side raised lateral decubitus position (i.e. lying on the left side) for 10 minutes. A horizontal beam X-ray taken across the table can then reveal as little as 2 ml of gas above the lateral liver border (Fig. 5.4).
Bone X-rays: Conventional radiographs of bones continue to play an important role in diagnosis of bone disease, particularly fractures, but also infection, neoplasia and degenerative conditions. Other investigations including bone scintigraphy, CT, MRI and ultrasound are often used, particularly if conventional X-rays are normal. If in doubt it is best to discuss with a radiologist.
Contrast radiology
Contrast materials: Barium sulphate is the best agent for directly outlining the GI tract. It is insoluble in water and is not absorbed. An aqueous suspension is non-irritant and very radiodense. Barium investigations of the upper and lower gastrointestinal tracts have been largely superseded by endoscopy or cross-sectional imaging but are still occasionally employed.
Examples of contrast radiology:
Bowel contrast radiology: Any part of the gastrointestinal tract can be demonstrated using contrast. Most barium studies use a double contrast method. Following barium, air or carbon dioxide is used to distend the bowel and separate the barium-coated bowel walls. An anticholinergic agent such as hyoscine butylbromide (Buscopan) is sometimes given at the same time to abolish spasm, further improving the image.
Preparation for bowel contrast studies: For upper gastrointestinal studies, patients should be fasted overnight except for water. For a barium enema, bowel preparation is performed with laxatives (e.g. sodium picosulphate) and sometimes bowel washouts, so artefacts are removed (faecal lumps look similar to polyps) and small mucosal defects are not obscured.
Upper gastrointestinal tract: For examining the upper GI tract, barium suspension is given orally (barium swallow for oesophagus and barium meal for stomach and duodenum. Progress of contrast is observed by screening, with a moving image displayed on a screen. The radiologist usually selects representative spot films to summarise the examination. Screening is useful to study rapid GI motility as in swallowing; images can be studied later in slow motion.
Large bowel: The large bowel is examined by means of contrast material given rectally (barium enema). The lower rectum is often poorly shown so prior rectal examination and sigmoidoscopy is best to ensure low lesions are not missed.
With improved technology, CT is increasingly used for large bowel examination. It can be performed without laxative preparation where it would be acceptable to miss small polyps, for example in suspected obstructing lesions. CT can be useful in the frail elderly when a right-sided colonic cancer is suspected because of anaemia or a palpable mass. For a more complete examination, CT colonography (also known as CT coloscopy or virtual colonoscopy) requires full bowel cleansing. During the procedure, air or carbon dioxide is insufflated into the colon; the technique is sensitive enough to detect lesions larger than 1 cm. The investigation is quicker and less unpleasant than barium enema and has replaced it altogether in some units. Hundreds of images are produced and the best are viewed on workstations along with reconstructed axial and 3D images of the bowel lumen (see Fig. 5.5).
Small bowel: For small bowel examination, a barium meal may be ‘followed through’ into the small bowel, or contrast can be instilled directly into the proximal jejunum via a nasal or oral tube. In either case, the diagnostic yield is poor and these techniques are likely to be replaced by CT or MR studies of the small bowel or capsule endoscopy (see below).
Complications of barium contrast studies: The limitations of barium contrast studies are summarised in Box 5.2. There is a risk that contrast material may be aspirated into the bronchial tree, causing aspiration pneumonitis, so care must be taken when giving oral barium to patients with swallowing difficulties. CT scanning is safer and more likely to provide useful information such as the level and cause of obstruction, and associated pathology such as lung or liver metastases.
Some biliary investigations described in previous editions of this book (e.g. oral cholecystography and intravenous cholangiography) have been superseded by ultrasound and increased availability of endoscopic retrograde cholangio-pancreatography (ERCP, p. 65) and magnetic resonance cholangio-pancreatography (MRCP).
Magnetic resonance cholangio-pancreatography (MRCP) (Fig. 5.6 e and f): MRCP now produces images that rival the quality of ERCP. MRI differentiates tissues and organs by their varying water content. Bile and pancreatic juice are mostly water, hence MRCP gives clear images of bile in the gall bladder and ducts and outlines the pancreatic duct. It reveals filling defects caused by stones or tumours. MRCP can identify bile leaks, gallstones in the bile ducts, and duct obstruction from any cause. There are no known hazards. MRCP is increasingly used prior to ERCP for pancreatico-biliary investigation to reduce the number of patients requiring the more invasive investigation.
Fig. 5.6 Some techniques for demonstrating the biliary system
(a) and (b) Endoscopic retrograde cholangiography
The patient is sedated and a side-viewing gastroscope passed down so the tip reaches the second part of the duodenum. The ampulla of Vater is cannulated under direct vision and contrast medium injected to outline the bile ducts. (b) A large gallstone C is seen within the dilated common bile duct and a collection of radiopaque gallstones GS is seen in the gall bladder
(c) and (d) Percutaneous transhepatic cholangiography
A needle N is passed into the liver until it encounters a dilated duct. Contrast medium is then injected to outline the ducts. (d) Case study—this deeply jaundiced 57-year-old woman has grossly dilated intrahepatic ducts and complete obstruction of the proximal common bile duct in the porta hepatis at O. This was due to lymph node metastases from carcinoma of stomach. This method is employed less often nowadays because of the superior safety of other methods described here
(e) and (f) Magnetic resonance cholangio-pancreatography (MRCP)
The technique produces images of static fluid, thus the images are of native biliary and pancreatic secretions. Each image was obtained in one second using a thick slab ‘projection’ method that generates images very similar to ERCP. The pancreatic duct in each image is labelled P. (e) An example of normal biliary and pancreatic duct systems. (f) A small calculus, C, in the distal common bile duct. There is also mild dilatation of the pancreatic duct with some side branches visible
• Suspected bile duct stones, especially within the liver and for seeking retained stones after operation
• Bile duct strictures, particularly within the liver—post-surgical, cholangiocarcinoma
• Suspected sclerosing cholangitis
• Acute pancreatitis of unknown aetiology—MRCP reveals anatomical duct abnormalities
• Biliary-type pain with abnormal liver function tests in patients without stones on ultrasound
• Patients unsuitable for ERCP because they are intolerant of the procedure or have had previous gastrectomy
Percutaneous transhepatic cholangiography (PTC): Percutaneous cholangiography is rarely used for diagnosis but has occasional therapeutic indications. A long fine (22 G) ‘Chiba’ needle is passed percutaneously, directly into dilated intrahepatic ducts, and contrast injected to display the duct system (see Fig. 5.6c). This shows the configuration of extrahepatic duct obstruction from the proximal direction. Occasionally, PTC is employed to drain obstructed ducts after failed endoscopic placement of a drain or stent. In jaundiced patients, disordered blood clotting is likely so a clotting screen and platelet count should be performed before PTC, and any clotting disorder corrected.
Endoscopic retrograde cholangio-pancreatography (ERCP): This is described below (see Diagnostic and therapeutic duodenoscopy); its use in obstructive jaundice is described in detail in Chapter 18. The basic technique is illustrated in Figure 5.6 a and b.
Operative cholangiography and choledochoscopy: It is standard practice to perform operative cholangiography during open cholecystectomy. For laparoscopic cholecystectomy, some surgeons routinely perform operative cholangiography whilst others prefer no imaging at all for selected cases or else preoperative assessment using MRCP for cases deemed likely to have duct stones.
T-tube cholangiography: Following exploration of bile ducts for stones, a T-tube is often left in situ to drain the duct. The transverse limb of the T lies in the duct and the long limb drains out through an opening in the duct to the skin where it is connected to a drainage bag. About 1 week after operation, contrast can be injected along the T-tube to outline the biliary tree and show abnormalities such as residual stones, bile leakage and duct stenoses as well as confirming free drainage into the duodenum. If residual stones are still present they can be retrieved either at ERCP or sometimes by the radiologists via the T-tube itself.
Vascular Radiology (Angiography)
General principles and hazards of arteriography and venography
Further detail about applications of vascular radiology is given in Chapter 41.
The contrast medium is the same as that used for computed tomography (CT) and carries similar hazards, i.e. allergic reaction and nephrotoxicity (see Urography below). There is also the risk of complications from the cannulation, which may cause bleeding or thrombosis and, for arteries, wall dissection, arteriovenous fistula or false aneurysm formation.