Diagnosis and management of common postoperative problems

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11

Diagnosis and management of common postoperative problems

Introduction

Despite good preoperative assessment, surgical and anaesthetic technique and perioperative management, unexpected symptoms or signs arise after operation that may herald a complication. Detecting these early by regular monitoring and surgical review means early treatment can often forestall major deterioration. This chapter uses a problem-orientated approach to help junior (and more senior) doctors deal with such problems. The management of more serious complications is described in the next chapter.

Managing problems such as pain, fever or collapse requires correct diagnosis then early treatment. Determining the cause can be challenging, particularly if the patient is anxious, in pain or not fully recovered from anaesthesia. It is vital to see and assess the patient and if necessary, arrange investigations, whatever the hour, when deterioration suggests potentially serious but often remediable complications. Consider also whether and when to call for senior help.

Postoperative pain

Some types of wound are more painful, for example vertical abdominal incisions and skin graft donor sites. It is better to prevent pain pre-emptively than react to established pain.

Methods of management

Postoperative pain can be minimised by preoperative counselling, perioperative measures and postoperative analgesia. Counselling lets the patient know the probable extent of pain, the plans for pain relief and the likely degree of mobility after operation. During the operation pre-emptive analgesia ensures that pain does not become established.

This may involve:

• Long-acting analgesic drugs given intravenously

• Local anaesthetic infiltration into the wound edges at the end of the operation with a long-acting agent, such as bupivacaine

• Regional nerve blocks (e.g. intercostal nerves for upper abdominal surgery using a transversus abdominis plane (TAP) block)

• Epidural analgesia using local anaesthetic and often morphine, during and after abdominal and pelvic surgery. These do not influence the rate of anastomotic leakage

• Non-steroidal analgesics given before the patient awakes by suppository or intravenous injection. These must not be given to patients with known allergy to aspirin or other NSAIDs, a history of severe asthma or angio-oedema, bleeding disorders, renal impairment, hypovolaemia or pregnancy. Mild asthma is not a contraindication. It is also unwise to use these in operations with a high risk of haemorrhage

Analgesia for major surgery and trauma

(see Box 11.1)

Many hospitals now provide an acute pain service, run by anaesthetists and specialist nurses. This team can plan individual analgesic strategies and help deal with pain problems as they arise. True objective rating of pain is difficult but some form of visual analogue scale chart can be helpful (Fig. 11.1).

Following major abdominal and perineal operations epidural analgesia using local anaesthetic drugs and morphine can be invaluable. A single dose can provide anaesthesia for the operation, e.g. transurethral prostatectomy, plus several hours of complete postoperative analgesia. For more extensive surgery, an epidural cannula can be left in situ to allow ‘topping-up’ to extend postoperative analgesia. These patients need careful observation for signs of toxicity, severe hypotension or respiratory depression. Note that moderate hypotension is merely an indication of satisfactory sympathetic blockade.

For major surgery and trauma where epidural analgesia is inappropriate, the analgesic dose needs to be enough to eliminate the pain without causing dangerous side-effects, and to be given often enough for continuous pain relief. Effective pain control can be achieved by allowing patients to give themselves small intravenous increments of opiates using a patient-controlled analgesia (PCA) device (Fig. 11.2). This allows presetting of the incremental dose (often 1 mg of morphine), with a 5 minute lockout to prevent it being given too frequently, as well as control of the total dose. Continuous effective pain relief is thus easily achieved and the total dose used is often less than with intermittent injections. This technique causes minimal sedation and respiratory depression whilst maintaining excellent continuous analgesia, although it can cause opiate-induced nausea.

Excessive postoperative pain

If the pain is not controlled by an apparently adequate dose and frequency of analgesia, complications should be suspected. The dose should first be reviewed in relation to the expected severity of pain and the weight of the patient.

• Local postoperative complications should be considered. Wound pain may be caused by pressure from a haematoma. In limb trauma, bleeding into or inflammatory oedema in a fascial compartment must be diagnosed before ischaemia ensues (‘compartment syndrome’). Wound pain increasing after the first 48 hours may be caused by infection. The wound is unusually tender even before redness and induration develop and there is usually a pyrexia. Other complications with lower limb pain include deep vein thrombosis and acute ischaemia. Lastly, major co-morbid conditions may be the cause of pain, for example myocardial ischaemia, or a fractured neck of femur may follow falling out of bed

• Major complications in the operation area. After an abdominal operation, excessive pain can be caused by intra-abdominal complications. These include haemorrhage, anastomotic leakage, biliary leakage, abscess formation, gaseous distension due to ileus or air swallowing, intestinal obstruction, urinary retention and bowel ischaemia, any of which is likely to require reoperation. Constipation may also cause late postoperative pain

As a rule, serious complications cause deterioration in the patient’s general condition, whereas the patient remains well with less serious complications such as urinary retention or constipation.

Pyrexia (see Fig. 11.3)

Fever is a common postoperative observation not always caused by infection. Pyrexia within 48 hours is usually caused by basal lung atelectasis and should be treated with physiotherapy and mobilisation. After this period, a search should be made for a focus of infection. The common ones are superficial or deep wound infection, chest infection (pneumonia), urinary tract infection and infection of an intravenous cannula site. If there is a central venous line, infection should always be suspected in unexplained pyrexia. Unfortunately, this can only be diagnosed by removing the line and culturing the tip for organisms. Blood cultures alone are often positive but do not reveal the source of infection. Patients usually recover spontaneously once the central line is removed.

Common non-infective causes of pyrexia include transfusion reactions, wound haematomas, deep venous thrombosis and pulmonary embolism. Pyrexia is sometimes the only sign of an idiosyncratic or allergic drug reaction. A rare cause is malignant hyperpyrexia following general anaesthesia.

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