Hereditary Stomatocytosis

Published on 22/03/2015 by admin

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Last modified 22/03/2015

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Chapter 454 Hereditary Stomatocytosis

Hereditary stomatocytosis includes a rare group of dominantly inherited hemolytic anemias in which there are characteristic morphologic changes in the RBCs and increased red cell cation permeability. The RBCs are cup shaped, creating a mouth-shaped area (stoma) of central pallor instead of the usual circular area of central pallor. Hereditary stomatocytosis is classified by the RBC hydration status. The two major varieties are either overhydrated (hydrocytosis) or dehydrated (xerocytosis).

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