Goodpasture Disease

Published on 27/03/2015 by admin

Filed under Pediatrics

Last modified 27/03/2015

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Chapter 511 Goodpasture Disease

Goodpasture disease is characterized by pulmonary hemorrhage and glomerulonephritis. The disease results from the attack of these normal organs by antibodies directed against specific epitopes of type IV collagen within the alveolar basement membrane in the lung and glomerular basement membrane (GBM) in the kidney. The etiology of these antibodies is unknown.

Clinical Manifestations

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