Continuous Peripheral Nerve Blocks

Published on 06/02/2015 by admin

Filed under Anesthesiology

Last modified 22/04/2025

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2 Continuous Peripheral Nerve Blocks

Acute pain medicine is a subspecialty of anesthesiology, and the capability to administer continuous nerve blocks (neuraxial, paraneuraxial, and peripheral) is a growing and essential skill of the acute pain specialist. Continuous nerve blocks provide analgesia over a continuum of hours to weeks and allow the clinician to control the spread, density, and duration of the nerve block, putting him or her firmly in control of the patient’s analgesic requirements. These advances stimulated the ongoing development of continuous peripheral nerve blocks, the subject of this chapter. Research into reversible yet long-acting local anesthetics has been ongoing for many decades, but to date no effective long-acting drug is available—likely because long-lasting undesired side effects of the block will accompany the long-term desired effects of the block.

Advances in perineural techniques focus on improving catheter placement, thus reducing the diminishment of analgesia after the initial bolus injection. There are three primary techniques for placing perineural catheters: the nonstimulating catheter technique, the stimulating catheter technique, and the ultrasonography-guided technique. Most physicians use all three techniques in combinations that depend on the location of the block and the clinical situation; only a few use a single technique exclusively. The most popular and perhaps most effective way of placing a perineural catheter is under ultrasonographic guidance with or without nerve stimulation needle placement using a stimulating catheter.

General Approaches to Continuous Catheter Placement

Stimulating Catheter Technique

During stimulating catheter placement, an insulated needle (typically a Tuohy needle) is placed near the nerve to be blocked under nerve stimulator or ultrasonographic guidance; no bolus injection is made at the time of needle placement. The next step is to place a catheter with an electrically conductive tip through the needle; electrical stimulation is now performed through the catheter. If a bolus injection is made to expand the perineural space, 5% dextrose in water is used rather than saline or local anesthetic; the latter two will impair the nerve stimulation needed for correct catheter placement using this technique. This technique has more steps than a nonstimulating method. The primary success rate with this technique equals that of the nonstimulating technique, but in theory it has a higher secondary block success rate because of more precise catheter placement. Numerous formal outcome comparisons (nonstimulating vs. stimulating catheters) have been completed, and the findings show analgesic and even surgical outcomes significantly better with use of stimulating catheters. For optimum results, the stimulating catheter should be placed to block the entire region (limb) where the pain originates—for example, the brachial plexus in the case of shoulder surgery or the sciatic nerve in the case of ankle surgery (combined with a saphenous nerve block). Conversely, if only one of a number of nerves that innervate the area (limb) where the pain originates is blocked, such as the femoral nerve after major knee surgery, there seems to be no difference between the analgesic and surgical outcomes of stimulating and nonstimulating catheters. This is especially true if effective multimodal analgesia is also used.

Technique Details

Nonstimulating Catheter Technique

An insulated stimulating needle is directed near the peripheral nerve to be blocked with a stimulator current output of 1.5 mA, or under ultrasonographic guidance. The final needle position is confirmed by (1) observing an appropriate motor response with the nerve stimulator current output set at 0.3 to 0.5 mA, with a frequency of 1 to 2 Hz and a pulse width of 100 to 300 µsec; or (2) demonstrating the needle to be near the nerve by ultrasonography. When ultrasonography is used, it is customary to inject a small volume of fluid through the needle to demonstrate its spread around the nerve—so-called hydrodissection and doughnut sign formation. The needle is often attached to a syringe by tubing from a side port (Fig. 2-1). This arrangement allows the physician to aspirate for blood or cerebrospinal fluid during needle placement and thus minimize unintentional intravascular or intrathecal injection; however, this can give potentially dangerous false-negative results because the suction produced by needle aspiration causes the surrounding tissue to obstruct the needle tip, thus allowing injection of local anesthetic into the intravascular or intrathecal space. Ultrasonography theoretically protects against missing the obstruction, although this depends on the operator’s skill.

Once needle position is finalized the needle is held steady and the bolus of local anesthetic solution is injected in divided doses. Sometimes saline rather than a bolus injection of local anesthetic is used, as many believe that saline eases passage of the subsequently placed catheter and minimizes confusion of bolus local anesthetic effects with effects of the catheter injection. The catheter, typically an insulated 19- or 20-gauge epidural (multiorifice) catheter, is advanced 3 to 5 cm past the distal end of the needle. After catheter insertion the needle is removed and the catheter is secured with the operator’s preferred technique, one of which is a combination of medical adhesive spray, Steri-Strips, and transparent occlusive dressing. Other physicians tunnel the catheter subcutaneously to secure it.

A variety of local anesthetic solutions are used for the block. Many prefer ropivacaine, but this choice depends on the clinical situation. More often than not during this method a bolus (20 to 40 mL) of the local anesthetic is injected through the needle before catheter insertion and provides the primary block. This is then followed by catheter placement and an infusion of local anesthetic solution through the catheter, producing what many call the secondary block (see Fig. 2-1C).

Unfortunately, catheters often curl when advanced, making it difficult to follow their eventual path with ultrasonography. Although some techniques of visualizing the catheter tip with color Doppler have been proposed, no fully satisfactory method is available to predictably identify the ultimate catheter tip location. After catheter placement, hydrodissection has been proposed as a means of identifying the catheter tip; however, if the catheter position proves faulty at this point the entire procedure needs to be repeated.

When using ultrasonographic guidance for catheter placement, a second person with a “third educated hand” is required to place the catheter: one hand holds and manipulates the needle, one hand holds and manipulates the ultrasound probe, and one hand places the catheter. If the “third educated hand” is not available, the operator removes the ultrasound transducer probe from the field and puts it down, leaving the operator with a free hand to place the catheter. This technical weakness—that catheter advancement is not observed directly (ultrasonography) or indirectly (nerve stimulation)—explains the frequent secondary block failures encountered with this technique.

Stimulating Catheter Technique

The insulated stimulating needle (Fig. 2-2A) is directed to the peripheral nerve to be blocked as in the nonstimulating technique approach described earlier, using either a nerve stimulator current output of 1.5 mA or ultrasonographic guidance. Adequate needle position is confirmed by observing an appropriate motor response with either (1) the nerve stimulator current output set at 0.3 to 0.5 mA, with a frequency of 1 to 2 Hz and a pulse width of 100 to 300 µsec or (2) the “doughnut sign” seen after hydrodissection when ultrasonography is used. Only 5% dextrose in water should be used for hydrodissection; saline or local anesthetic impairs the electrical stimulation of the nerve and makes catheter placement with this technique difficult.

The needle is held steady in the desired position and, usually without injecting any solution through the needle, the negative lead off the nerve stimulator is clipped to the proximal end of the stimulating catheter, which is in turn advanced through the needle (Fig. 2-2B). The desired motor response with catheter advancement through the distal end of the needle should be similar to that elicited during initial needle placement. If the motor response decreases or disappears, it usually indicates that the catheter is being directed away from the nerve with advancement. Using this paired needle and catheter assembly, the catheter can be withdrawn back into the needle without undue concern over catheter shearing. If refinement in catheter positioning is required, the distal catheter is withdrawn into the shaft of the needle. Then, a small positioning change is made to the needle, typically by rotating it clockwise or counterclockwise or by advancing or withdrawing the needle a few millimeters, and then the catheter is advanced again, similar to the earlier catheter positioning steps. This process may be repeated until the desired motor response is elicited during catheter advancement. The desired motor response should continue as the catheter is advanced 3 to 5 cm along the neural structures.

The ultrasound transducer probe is normally also removed during catheter placement to leave the operator with a free hand to place the catheter. However, because the catheter is being stimulated during advancement, indirect visualization of the catheter’s position is provided.

Fixation of the Catheter

Catheter dislodgement continues to be a problem during continuous catheter analgesia. In our experience, tunneling the catheter subcutaneously has eliminated a large number of catheter dislodgements. A variety of tunneling techniques are described. The first decision during catheter tunneling is whether a skin bridge will be used. A skin bridge allows easier catheter removal and is typically used during a short-term catheterization (1 to 7 days). Catheter tunneling without a skin bridge is often used for longer catheterizations (>7 days) and has the theoretic advantage of minimizing catheter infection.

For a skin bridge technique, the stylet of the Tuohy needle (Fig. 2-3A) is used as the needle guide and directed to enter the skin 2 to 3 cm from the catheter exit site. If a non–skin bridge technique is chosen, the stylet is placed through the skin at the catheter exit site. In each technique the stylet is advanced to the desired skin exit site subcutaneously over a distance of approximately 10 cm, or the length of the stylet. The Tuohy needle is then advanced in a retrograde fashion over the stylet (Fig. 2-3B). Next, the stylet is removed and the catheter is advanced through the needle (Fig. 2-3C) until it is secure and the needle can be withdrawn, leaving the catheter tunneled. If a skin bridge technique is used, a short length of plastic tubing is inserted to protect the skin under the skin bridge (Fig. 2-3D).

After the catheter tunneling has been completed, the catheter should be checked for stable distal catheter tip position. For this purpose, a device such as the SnapLock (Arrow International, Reading, Penn), which allows continuous nerve stimulation through the catheter, is attached to the catheter. The syringe containing the local anesthetic is attached to the SnapLock (Fig. 2-4) and then, while stimulation of the catheter continues to elicit a motor response, the injection of local anesthetic is started. The evoked motor response should cease immediately on injection due to the dispersion of the current by the conductive fluid. Saline injected through the catheter will result in the same discontinuation of motor response, but plain sterile water will not. More current will therefore be required to produce a motor response.

Pearls

Patient anxiety is the major cause of discomfort during continuous nerve block placement; hence, appropriate sedation or verbal reassurance through explanation of the procedure is important. A continuous block will typically take a slightly longer time to place than a single-injection block. Appropriate infiltration of local anesthetic at the site of the block and at the site of tunneling is important and should not be rushed. When making adjustments in needle position while establishing the initial optimum catheter position, ensure that the tip of the catheter is fully inside the shaft of the needle before needle manipulation. Continuous peripheral block catheters are often left in place for an extended time, so adherence to sterile technique is required. After catheter placement the site should be covered with a transparent dressing so that daily inspection of the catheter exit site and skin bridge area can be made for signs of inflammation.

The entire limb is usually insensitive for the duration of the continuous block. Blockaded nerves vulnerable to injury, external pressure, or traction should be specifically protected. These commonly include the ulnar nerve at the elbow, the radial nerve at the mid-humeral level, and the common peroneal nerve at the fibular head area. Ambulatory patients with a continuous brachial plexus block in place should always use a properly fitted arm sling to prevent traction injury to the brachial plexus or injury to the radial nerve by the sling. Pressure or undue traction to the ulnar nerve (hyperflexion at the elbow) should be avoided. When the block involves the quadriceps and hamstrings muscles, there is a possibility of falling with ambulation in the immediate postoperative period; leg splints should be routinely fitted and patients should not ambulate unassisted.

When removing the catheter it is ideal to withdraw it after full limb sensation has returned. Radiating pain experienced during catheter removal may indicate that the catheter is intertwined with a nerve or nerve root. Surgical removal of catheters after fluoroscopic examination may be indicated if the radiating pain persists with removal attempts. This is an extremely rare occurrence.