Chemical peels and dermabrasion

Published on 22/05/2015 by admin

Filed under Plastic Reconstructive Surgery

Last modified 22/05/2015

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CHAPTER 79 Chemical peels and dermabrasion

Physical evaluation

Table 79.1 Fitzpatrick skin classification

Type Color Reaction to sun exposure
I White Always burns/never tans
II White Usually burns/tans with difficulty
III White Sometimes mild burn/average tan
IV Moderate brown Rarely burns/tans with ease
V Dark brown Very rarely burns/tans very easily
VI Black Never burns/tans very easily

Data from Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol 1988;124:869.

Anatomy

The skin consists of three layers: the epidermis, dermis, and subcutaneous fatty tissue. Appendageal structures, including hair follicles, sebaceous glands, eccrine glands, and apocrine glands pierce these layers and are required for wound healing following partial-thickness injury. The efficiency of healing and re-epithelialization is related to the concentration of adnexal structures, which decreases with increasing depth of injury.

The most superficial portion of the skin is the stratum corneum, which is a non-viable layer of cornified cells serving as a protective barrier. It becomes disorganized and looser with aging and photodamage. The remainder of the epidermis consists of continually rejuvenating cells that migrate from the bottom of the epidermis toward the surface.

The dermis is a thicker layer consisting of the superficial papillary dermis and the deeper reticular dermis. It lies beneath the epidermis and contains a vascular network, hair bulbs and sebaceous, apocrine and eccrine glands. The subcutaneous tissue lies deep to the dermis.

Aging of the skin affects both the epidermis and dermis and is exacerbated by actinic damage. Aging causes epidermal hyperplasia, atrophy and dysplasia, producing an atrophic and flat epidermis. Dermal connective tissue shows progressive diminution with loss of much of the reticular dermis. Collagen fibers become degenerated and thickened. Reduction of the amount of collagen leads to thinning of skin. The dermis of actinically damaged skin exhibits elastosis, the presence of thickened, degraded elastic fibers. Separating the solar elastotic material from the epidermis is a thin zone of normal appearing dermis largely composed of collagen, called the Grenz zone. Additionally, aging causes loss of dermo-epidermal papillae and reduction in the melanocytes. These histological changes are responsible for the clinical signs of aging and sun damage including wrinkling, laxity, and pigment changes. Cutaneous resurfacing is intended to reverse these changes.

Technical steps

Pretreatment helps to minimize or prevent adverse pigmentation changes. Pretreatment consists of a 2–6-week course of 0.05% Retin-A once a day with topical 4% hydroquinone twice a day added for darker skin patients to decrease melanin formation and hyperpigmentation. Alpha-hydroxy acids in combination with Retin-A help to even out skin texture, improving the outcome of resurfacing. Routine skin care, including the use of cleansers, moisturizers and sunscreens, must be emphasized to improve skin quality.

Superficial peeling agents such as Jessner’s solution, Unna’s paste, salicylic acid and the alpha hydroxy acids penetrate to the epidermal–dermal junction. Trichloroacetic acid (35%) is a medium depth peel that penetrates deep to the epidermal–dermal junction. Phenol–croton oil peels and dermabrasion may penetrate into the upper to mid reticular dermis. In general, aesthetic improvement, morbidity and healing time are directly related to the depth of injury.