What Is the Best Treatment for Plantar Fasciitis?

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Chapter 67 What Is the Best Treatment for Plantar Fasciitis?

Plantar fasciitis is a painful heel syndrome of unclear cause. Chronic or acute injury to the origin of the plantar fascia at the medial tubercle of the calcaneus is thought to produce a cycle of microtrauma and degenerative changes. Plantar fasciitis affects both active and sedentary adults with studies reporting that up to 10% of runners and a similar proportion of the general population are affected.14 A significant occurrence also is reported in military personnel and professional athletes.5,6 Increased body mass index, extended time standing, and limited ankle dorsiflexion are risk factors predisposing to plantar fasciitis.7 The high prevalence, substantial pain, and decreased tolerance for activity result in large numbers of patients seeking treatment. The cumulative number of office visits in the United States is estimated to be nearly 1 million visits each year.1

TREATMENT

Plantar fasciitis tends to improve in most cases regardless of the treatment selected.811 As a result, conservative management is effective for nearly 90% of patients.12,13 The conservative treatments used in management of plantar fasciitis vary widely and are dependent on physician specialty.1 Common treatments include nonsteroidal anti-inflammatory drugs (NSAIDs), stretching, insoles, taping, physical therapy, and night splints. If these simple and noninvasive modalities prove ineffective, additional treatment options include iontophoresis, injections, extracorporeal shock wave therapy (ESWT), and surgical treatment. This chapter reviews the various treatment methods for plantar fasciitis, and the effectiveness and safety of these treatments as supported by the best available evidence.

Stretching

Stretching protocols for the treatment of plantar fasciitis include stretching the Achilles tendon with or without stretching of the plantar fascia. Limited evidence is available from controlled trials to establish the effectiveness of stretching.14 Prospective studies comparing a plantar fascia–specific stretching protocol before the first morning steps and Achilles tendon stretching for treating chronic plantar fasciitis found a greater improvement in pain symptoms with the plantar fascia–specific stretching after 8 weeks (Level of Evidence II).15 Long-term follow-up at 2 years was incomplete but suggested no difference between Achilles tendon stretching and the plantar fascia–specific groups, although both groups showed improvement (Level of Evidence III).16

Orthoses

The use of orthoses is intended to change loading characteristics of the plantar aponeurosis. Studies using cadaveric limbs suggest that support of the medial longitudinal arch can decrease strain of the plantar aponeurosis.21 Several randomized, controlled trials have examined the use of insoles in management of plantar fasciitis. A recent study comparing custom insoles, sham insoles, and prefabricated insoles found minor improvement in symptoms 3 months after treatment with prefabricated or custom insoles compared with sham (Level I).22 Prefabricated insoles have been found to be as effective as custom insoles at a reduced total cost.2224 Insoles may be equally effective and offer improved patient compliance compared with night splints.24,25 A randomized, placebo-controlled, double-blind study conducted with 101 patients compared magnetic insoles with sham magnetic insoles and found no statistically significant improvement in pain symptoms after 8 weeks of treatment (Level II).26

Night Splints

Tension night splints stretch the plantar fascia over several hours while the patient sleeps by maintaining a constant ankle dorsiflexion. A trial comparing night splints with conservative treatment with conservative treatment alone found no significant difference in symptoms (Level I).27 Roos and coworkers28 compared insoles with night splints and found no significant difference in pain reduction and improved compliance with insoles (Level II). 28 Three studies reported that patients find night splint treatment uncomfortable and difficult to maintain, resulting in decreased compliance.24,28, 29 A systematic review found that the evidence for the effectiveness of night splints is inconclusive (Level II).3

Iontophoresis

Iontophoresis uses an electrical potential generated by bipolar electrodes to transfer charged ions and ionizable materials including some medications through the skin to provide anti-inflammatory or analgesic treatment.31 Conflicting results have been published for the effectiveness of dexamethasone iontophoresis. In a double-blind study with 39 subjects comparing iontophoresis using dexamethasone with a placebo, significant improvement on the Maryland foot score was reported at the end of the 2-week treatment period (3.80; 95% confidence interval [CI], 0.76–6.84) but not after 1 month (0.30; 95% CI, −2.16 to 6.76) (Level I).31 A second randomized, controlled trial with 31 subjects compared iontophoresis with taping and 0.4% dexamethasone, 5% acetic acid, or 0.9% NaCl placebo. The graphical data presented in the study indicate no statistically significant improvement with dexamethasone treatment in six measured outcomes at 4 weeks and less relief of pain symptoms compared with the control group at 2 weeks of treatment. In the group treated with acetic acid, there was a significant improvement in morning stiffness at 4 weeks with no reported statistically significant difference in three measures of pain at 4 weeks and no significant improvement compared with placebo in all six parameters at 2 weeks (Level I).18

Steroid Injection

Previously published reviews have found limited evidence to support the use of steroid injections in the treatment of plantar fasciitis.3,8 Steroid injection with and without nerve block was compared with placebo in a double-blind, randomized, control trial with 91 participants (Level I).32 The study found a statistically significant benefit at 1 month with steroid injection but not at 3 and 6 months. In addition, it was reported that tibial nerve block was not effective at relieving pain associated with steroid injection. A prospective study with 132 patients comparing steroid injection with ESWT or placebo found a statistically significant improvement in pain symptoms for the group receiving steroid injection over ESWT or placebo (Level II).33 The participants in this study reported VAS pain scores that were significantly lower than for the control and ESWT groups at 3 and 12 months. Potential adverse side effects of steroid injection include fat pad atrophy and plantar fascia rupture.

Extracorporeal Shock Wave Therapy

ESWT utilizes application of mechanical waves similar to those used in lithotripsy but of lower energy density, usually less then 0.36 mJ/mm2 per pulse. Therapy consists of 500 to 6000 pulses delivered at 2 to 4 Hz to treat plantar foot pain. The mechanism by which ESWT provides benefit is investigational. Current theories include stimulation of healing after increased release of growth factors and neovascularization in the environment of local tissue injury35,36 or alteration in the chemical function of small axons producing analgesic effects.37,38 The possibility of a noninvasive treatment for chronic plantar fasciitis has generated significant interest, and several studies investigating the effectiveness of this technique have been published. Many of these trials are not of sufficient quality to provide a reliable assessment of the effectiveness of ESWT.3,8, 39, 40 The studies investigating ESWT have been in many cases sponsored by the equipment manufacturers, and the randomized control trials have produced conflicting results. Good quality, randomized, placebo-controlled, double-blind clinical trials have found no significant benefit to ESWT,4143 whereas other randomized, controlled trials4447 have found ESWT to be beneficial. The reasons for the discrepancy in reported results are unclear. A lack of uniformity of therapy exists from study to study, with differing methods for assessment of therapy, and in some studies, significant problems with study design have been reported.3,40 Differences also exist in the definition of the terms high energy and low energy, as well as in the amount of energy used in various studies. No controlled trials adequately define and identify indications for high- or low-energy protocols for ESWT. In addition, differences in criteria for patient inclusion in the studies make it difficult to compare the trials directly. Table 67-1 summarizes double-blind, randomized studies comparing ESWT with placebo. The reported adverse reactions, including skin redness, bruising, pain, numbness, tingling, and local swelling,42,44, 46 likely do not pose serious health risks. However, clear evidence supporting the use of ESWT treatment in the treatment of plantar fasciitis has not been reported.

Surgery

No randomized, controlled trials compare patients undergoing surgical treatments with a control population. Surgical treatment is considered for the approximately 10% of patients who do not respond to conservative treatment. Surgical treatment options include percutaneous plantar fasciotomy, endoscopic plantar fasciotomy, or open fasciotomy.48,49 Cryosurgery is another proposed treatment that was reported in one case series to result in improvement of symptoms.50 Complications of surgical treatments include forefoot stress fracture, calcaneal fracture, medial or lateral column pain, nerve injury, infection, and instability.51,52 For surgical treatments, published case series report that between 75% and 95% of patients responded with improvement in measured symptoms after surgical treatment, with up to 27% having residual pain symptoms and 20% reporting activity restriction.8,49,5356 Increasing body mass index is a risk factor for poorer response to surgical treatment.57 A study comparing plantar fascia release of 25%, 50%, or 66% of the insertion by open or endoscopic procedures reports that increasing lateral column pain symptoms occurred with increased percentage of plantar fascia release.51 Limited evidence is available to suggest when surgical treatment should be recommended or to guide the choice of surgical treatment.

Open Fasciotomy.

Medial fasciotomy can be performed with local or general anesthesia. The plantar fascia is approached through an incision beginning medially and extending to the plantar aspect of the foot to allow exposure and release of the deep and superficial fascia of the abductor hallucis brevis muscle. Further dissection is used to identify and transect the medial aspect of the central plantar fascial band.58 For patients with neurologic symptoms resulting from suspected compression of the first branch of the lateral plantar nerve, which innervates the abductor digiti quinti (Baxter’s nerve), fasciotomy is accompanied by decompression of the nerve through release of the deep fascia of the abductor hallucis.59 Other authors advocate proximal release of the tarsal tunnel when neurologic symptoms suggest that refractory heel pain is associated with both plantar fasciitis and tarsal tunnel syndrome.60 No controlled trials adequately compare isolated plantar fasciotomy with techniques that incorporate release of Baxter’s nerve or the tarsal tunnel. The open technique also allows for the removal of a prominent plantar heel spur when present. No controlled trials have determined whether removal of a spur improves outcomes when compared with soft-tissue release only.

Other Treatments

The application of topical wheat-grass cream has been proposed in treatment of plantar fasciitis. A randomized, placebo-controlled double-blind study conducted with 80 patients found no statistically significant improvement resulting from treatment at 6 and 12 weeks. Primary outcome measures were a VAS for first-step pain in the morning and the Foot Health Status Questionnaire.63 No further studies on this treatment have been reported.

Irradiation of skin or soft tissue with low-power lasers has been proposed as an agent for pain management in plantar fasciitis.64 A single randomized, placebo-controlled, double-blind study conducted with 32 patients found no statistically significant improvement in 6 measured parameters during a series of treatments or 1 month after therapy. Adverse reactions were minimal (Level I).65

RECOMMENDATIONS

Limited evidence supports the recommendation of any one therapy in the treatment of plantar fasciitis.40 As a result, the use of less costly and less invasive treatment modalities such as stretching, taping, NSAIDs, orthoses, and night splints remain first-line therapies for plantar fasciitis. The failure of these conservative modalities may lead to the need for more costly or invasive treatments including casting, iontophoresis, injection, ESWT, or open or endoscopic plantar fasciotomy.

Studies for several of these treatments have produced conflicting results. Recommendations with grade of evidence for specific treatments and references are summarized in Table 67-2. Problems with study design have been recognized for several published trials and include description of randomization procedures, concealment of allocation, use of intention-to-treat analysis, absent or ineffective blinding, and duplicate publication of previously published results.2,3

TABLE 67-2 Summary of Recommendations

RECOMMENDATIONS LEVEL OF EVIDENCE/GRADE OF RECOMMENDATION REFERENCES

B 14, 15

B 14, 17

I 19 B 2224 B 14, 28 I 24, 29, 65 I 26 I 30 I 18, 31 B 32, 33 I 34 I 63 I 64 I 4146 C 49, 51, 5357

Plantar fasciitis tends to improve spontaneously, and in most of the comparative studies of treatment for plantar fasciitis, it was found that both the treatment groups and the control groups improved with time.3,8, 11 Conservative treatment is effective for nearly 90% of patients.12,13 No evidence supports the use of rest and ice, and limited evidence supports NSAID use in the treatment of plantar fasciitis. These treatments are effective general measures used in conservative management of many musculoskeletal complaints and may be considered for adjunctive therapy for treatment of plantar fasciitis in absence of contraindications. Prefabricated insoles, plantar fascia–specific stretching, and taping techniques should be considered as part of conservative treatment for short-term improvement in symptoms, but evidence for their efficacy is also limited.

The optimal period of conservative treatment before considering more invasive treatments has not been determined. Most studies examined the effectiveness of conservative treatments at 3 months, 6 months, or 1 year. When symptoms persist despite conservative treatment, steroid injections may be considered for short-term relief of symptoms but are associated with plantar fascia rupture and fat pad atrophy. Botulinum toxin injection and acetic acid iontophoresis may be considered, but the effectiveness of each is supported by only a single, small randomized trial. Casting and cryosurgery are additional proposed therapies, but evidence is lacking to establish effectiveness of these treatments. Available evidence does not provide convincing support for the effectiveness of night splints, steroid iontophoresis, ESWT, magnetic insoles, laser therapy, or topical application of wheat grass. Patient who do not respond to nonoperative management may consider surgical treatment with endoscopic or open release of 50% or less of the plantar fascia. Reported complications of surgery include persistent pain, fracture, nerve injury, infection, and instability. No randomized controlled trials compare surgical treatment with a control population, but there have been several reports of series of patients achieving satisfactory results with either open or endoscopic plantar fasciotomy.

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