What is manic depression (bipolar disorder)?

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1 What is manic depression (bipolar disorder)?

1.2 What is bipolar affective disorder?

Psychiatrists may appear to be always changing the names of the illnesses that they treat but this is not always done just to confuse the innocent! Manic depression is a term that has been used for more than a century to cover psychiatric illnesses with the fundamental symptom of a mood change. Fifty years ago the term would have been used widely to cover not only those patients who had manic episodes but also to include those who only experienced severe depression. In the 1960s it became apparent that there are major differences between those patients that experience mania and those that only suffer from depression. The differences are particularly in the course and the family history of the two types of mood illness. However, the considerable overlap has always been recognised. In order to indicate the separation, two new terms were adopted: unipolar and bipolar–unipolar depression for those patients that only experience depression and bipolar affective disorder for those that experience mania (and usually also depression). It would make logical sense to also have a unipolar mania category but in fact the unipolar manics are so similar to the bipolars that this term has not been popular (see Q 1.13).

Manic depression is an unusual illness in that a number of people have a bipolar illness that is currently undiagnosed because so far they have only suffered from depression. Even though the illness might have started with depression in the teenage years it is only when mania appears in the twenties that the diagnosis can be made. The illness affects both genders in essentially the same way.

The terms bipolar disorder and manic depression are now commonly used to describe the same illness and this book will follow that practice.

1.3 What do you call recurrent depression with hypomania?

The dividing line between mania and hypomania is not easy to demarcate (see Q 1.7); however it is worthwhile making this distinction because it affects decisions about treatment (Fig. 1.1). For this reason a different name is given to depression with mania–bipolar I–in contrast to depression with hypomania–bipolar II. There have been attempts to define bipolar III and IV based on family history and the effect of antidepressants but these have not really caught on.

image

Fig. 1.1 Prevalence of manic depression.

(Reprinted from Clin Appr Bipolar Disord 2002;1:10-14 by permission of Cambridge Medical Publications.)

1.4 What are the symptoms of mania?

The following example of a manic woman illustrates the range of symptoms and behaviours characteristic of mania (see also Box 1.1).

image Mood: In order to make a diagnosis of mania there must be a change in mood. This is usually elevated and she feels elated, ‘great’, ‘fantastic’. Extreme terms are used to describe a state that few of us reach. She may well be feeling ‘better than ever’, and in an exciting and unique way ‘connected with the whole world’. It is common to have never had such a good feeling in the whole of her life. One of the major problems later can be that she doesn’t feel that this is an experience that she would like to avoid; in fact she feels just the opposite because it is a feeling that one would want to seek out. The closest comparison is to feelings that a great success or achievement (or winning the lottery) can produce or the high that comes from drugs such as cocaine. The elation is often infectious and others can (at first at least) feel more cheerful in her presence and find a smile on their face. She looks happy but in an active, excited way rather than displaying a calm peaceful serenity.

However, not uncommonly it is irritability rather than elation that is felt and apparent to others. She can’t tolerate any disagreement but finds arguments everywhere, as her plans are being thwarted by others who see how unrealistic they are.

image Speech: She will talk non-stop and be difficult to interrupt. Staying quiet becomes impossible and dialogue is not needed–monologue is fine. In fact she does not even need an audience: you can see her wandering about, chatting away. Talking may not be enough–singing, shouting and laughter all form part of expressing her joy to the world.

Flight of ideas is the classic form of speech in mania (Box 1.2). Flight indicates the way ideas flow from one to another. The connections within the speech are usually apparent, in contrast to the thought disorder of schizophrenia which is much more obscure. But connections are too free and frequent so that distractions in what she sees or hears send her off on a new track. Alternatively, internal connections or personal memories may suddenly intervene. Playing with language is common as punning or rhyming takes over the flow for a while. The digressions mean that the goals of speech are quickly lost and so little is achieved in any conversation.