Primary lesion of chickenpox (varicella): a discrete, clear vesicle with central umbilication; it later turns cloudy, then develops a crust. There is a flare of erythema around the vesicle.

The evolving chickenpox vesicle is crusty and cloudy, and usually collapses in the middle.

Varicella lesions are diffusely scattered. The lesions are very pruritic. Deep lesions may scar.

Varicella lesions in varying stages of development and widely scattered. Before the exanthem, there is typically fever, cough, and itchy eyes.