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Chapter 15


Shared Spirochetal Features




• Many spirochetal diseases follow a similar clinical course, commonly lasting from months to years if not treated, and induce tissue-damaging immune responses (Box 15-1).

II Treponema Species

• The pathogenic treponemes (T. pallidum, T. pertenue, and T. carateum) cannot be distinguished morphologically or serologically, but they exhibit distinctive clinical manifestations and epidemiology.

Shared treponemal properties

1. Treponemes are shorter than Borreliae and possess three axial filaments.

2. Anaerobic (or microaerophilic) organisms that cannot be grown in the laboratory

3. Visualization

4. Serologic tests (Box 15-2)

5. Pathogenesis