Second Malignant Neoplasms
Summary of Key Points
• Subsequent malignancies after successful treatment for cancer occur in a meaningful minority of persons.
• Etiology is often multifactorial and includes known hereditary conditions, unrecognized genetic predisposition, primary cancer, therapeutic exposures, age, and lifestyle practices.
• Guidelines for screening are available for some but not all situations; health care providers and patients should be aware of such guidelines.
• Further research is needed to identify persons at highest risk so more useful preventive strategies can be developed.
