PREHOSPITAL AIRWAY MANAGEMENT: INTUBATION, DEVICES, AND CONTROVERSIES

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CHAPTER 10 PREHOSPITAL AIRWAY MANAGEMENT: INTUBATION, DEVICES, AND CONTROVERSIES

Prehospital trauma airway management is probably the biggest challenge faced by prehospital providers. These professionals must not only acquire but also maintain essential skills to adequately manage airway problems at the scene and during transport of trauma victims to trauma centers.

Endotracheal intubation is the definitive method of airway management. However, to acquire such skill requires significant training and practice. Although the emergency medical technician-basic (EMT-B) cur riculum contains an advanced airway module, the low frequency of these procedures makes it difficult for these professionals to maintain proficiency. In most systems, paramedics and flight nurses are the only professionals allowed to perform rapid sequence intubation (RSI). Therefore, there is a need for simpler ways to maintain a patent airway by emergency medical technicians, until the patient is delivered to a hospital. Several devices are now available and have been used by prehospital personnel when endotracheal intubation is not practical or possible. These alternate methods include bag-valve-mask with oral or nasopharyngeal airway, the laryngeal mask, and the esophageal-tracheal double lumen tube, popularized as the Combitube.

In this chapter, the indications for airway management in the prehospital arena, the different modalities, devices and techniques, the recognition of a difficult airway, and associated pitfalls will be discussed.

DIFFICULT AIRWAY

The Mallampati classification has been used for many years by anesthesiologists during preoperative evaluations for the identification of a difficult airway and to predict difficult intubation2 (Figure 1). It compares tongue size with the oropharyngeal space, and its reliability has been questioned because it does not take into account other factors that may make intubation difficult or impossible in the prehospital setting. However, if the patient is still able to follow simple commands, direct visualization of the oropharynx by asking the patient to open the mouth will give additional and important information to the astute prehospital provider. Rich3 described the 6-D methods of airway assessment: disproportion; distortion; decreased thyromental distance; decreased interincisor gap; decreased range of motion in any or all of the joints—atlanto-occipital, temporomandibular, and cervical spine, always present in trauma; and dental overbite.

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Figure 1 Difficult airway—the Mallampati score modified by Samsoon and Young.

(From Mallampati SR, et al: A clinical sign to predict difficult tracheal intubation: a prospective study. Can Anaesth Soc J 32:429–435, 1985.)

Identifying a difficult airway prevents patient deterioration or death. Alternative devices and strategies should be used when the diagnosis of a difficult airway is made. These include the laryngeal mask airway (LMA), Combitube, or bag-valve-mask.

WHICH STRATEGY SHOULD BE USED?

The strategies described as follows are alternatives to conventional bag-valve-mask with either a nasopharyngeal or an oropharyngeal airway.

Laryngeal Mask Airway

The LMA is one alternative to endotracheal intubation (Figure 2). Its use is particularly important in patients with difficult airways (defined later) and in patients treated in “unfriendly” environments (rain, dark, prolonged extrication, etc.). It also can be used as a rescue strategy following a failed RSI. Additionally, it can be used to facilitate intubation, which is obtained by passing the endotracheal tube through the LMA.

The insertion of the LMA is done blindly into the oropharynx, and it is usually tolerated without the need of neuromuscular blockade. The LMA lies in the hypopharynx in the supraglottic position. The successful placement of the LMA is independent of the Mallampati score, presence of a C-collar, or in-line immobilization of the neck. Spontaneous ventilation through the LMA is possible, and manual ventilation through the LMA is superior to bag-valve-mask ventilation, because the latter requires two hands to maintain a good seal. Studies comparing the success rates have shown that paramedics achieve higher levels of successful placement with the LMA compared to endotracheal intubation.4 The LMA may be particularly useful in patients with a difficult airway, since direct visualization of the cords is not required and neuromuscular blocking agents are not necessary. The advantages of the LMA over the Combitube (described next) include lower risk of malpositioning, no risk of esophageal intubation, and less trauma to the oropharynx. A major disadvantage of the LMA is that it does not protect against aspiration, which may carry significant risk in patients with intact airway reflexes. Another limitation of LMA is related to the difficulty in generating high airway pressures, which may lead to ineffective ventilation.5

Combitube

The Combitube consists of a device with two lumens. One of the lumens has an open distal end similar to an endotracheal tube, whereas the other lumen has a closed distal end, with several holes proximal to its balloon cuff. A second balloon of higher volume is located more proximally to the side holes, and it is used to secure the tube in position. The Combitube is inserted blindly and allows ventilation through either lumen. Following blind insertion, the distal tip is usually located in the esophagus. After inflating the oropharyngeal balloon, the esophageal cuff is inflated. Attempts to ventilate through the pharyngeal lumen will determine whether the distal tip is in the esophagus or trachea. If there is no change in the colorimetric, end-tidal carbon dioxide detector, or if breath sounds are absent, then the distal tip is in the trachea and the patient should be ventilated through the tracheal lumen (Figures 3 and 4).

The Combitube is a useful alternative to endotracheal intubation when an airway is not obtained after multiple attempts, when the airway is considered a difficult one, when direct visualization of the vocal cords by laryngoscopy is not possible at the scene, or when prehospital providers are not trained to perform orotracheal intubation. The great majority of patients brought to trauma centers after insertion of a Combitube will be ventilating and oxygenating well, and there is no need for immediate removal of the Combitube and orotracheal intubation. The Combitube is also useful in patients with significant maxillofacial trauma and cervical spine injuries. Because the esophageal cuff is immediately inflated after tube insertion, the Combitube offers protection against aspiration of gastric contents.

The Combitube is contraindicated in patients with intact gag reflex, or when upper airway obstruction is suspected. The Combitube is not available in pediatric sizes. Potential complications include injury to the pharynx and esophagus, and failure to recognize the exact location of the distal end and attempting to oxygenate and ventilate through the wrong lumen.

Confirmation of Orotracheal Tube Placement

Several factors contribute to endotracheal tube malpositioning and include poor lighting, limited access to the patient, insufficient suctioning, difficult airway, intraoral bleeding, vomiting, facial trauma, and airway swelling.

The gold standard for confirmation of adequate placement of an endotracheal tube is the direct visualization of the tube passing through the vocal cords. This is obviously not always possible considering less than ideal conditions at the scene. Auscultation of breath sounds also may be difficult at the scene, particularly in a noisy and chaotic environment.

The colorimetric, end-tidal carbon dioxide detector has been used by prehospital personnel to confirm endotracheal tube placement. In the presence of high levels of carbon dioxide, the device changes color from purple to yellow. The device has been deemed reliable; however, it lacks sensitivity in the setting of cardiopulmonary arrest due to the lack of pulmonary blood flow limiting carbon dioxide delivery. Therefore, approximately 15% of patients properly intubated in that setting would have their endotracheal tubes removed based on the lack of color change in the device.6 The opposite is also true, and a color change may be observed in patients who have ingested large volumes of carbonated liquids (beer, sodas, etc.), when the tube is in the esophagus or when the stomach has been insufflated with expired gas during bag-valve-mask ventilation.

Another way to determine proper placement of endotracheal tubes is the syringe aspiration technique. If the tube is properly placed in the trachea, the provider should not feel any resistance when attempting to aspirate air from the endotracheal tube (ETT) with a 60-cc syringe. If the tube is in the esophagus, upon negative pressure generated by the syringe, the wall of the esophagus collapses and resistance is felt by the provider.

CONTROVERSIES IN PREHOSPITAL INTUBATION

Prehospital Intubation in Traumatic Brain Injury

While an aggressive approach to airway management including ETI is standard-of-care for patients with severe TBI, it is notable that there is little evidence to support this approach.7 In fact, several recent studies have demonstrated an increase in mortality associated with prehospital intubation.810 It is not clear whether this represents a selection bias or a true detrimental effect of invasive airway management on outcome. The purported benefits of early intubation include reversal of hypoxia and airway protection from aspiration. However, the morbidity and mortality associated with these secondary insults may not be preventable or reversible with invasive airway management 10–15 minutes after the initial injury.11 In addition, there has been a recent increase in awareness of the adverse effects of positive-pressure ventilation on outcome, especially with hyperventilation and hypocapnia.

This makes patient selection for early intubation extremely important so as to maximize the benefit of the procedure. The use of the Glasgow Coma Scale (GCS) score alone to select patients to undergo prehospital intubation has several limitations. An early GCS score appears to have only moderate specificity in identifying severe TBI.12 In addition, the relationship between GCS score and aspiration is indirect at best. Aspiration events may occur prior to arrival of EMS personnel or with manipulation of laryngeal structures during intubation.11 Furthermore, hypoxemia may be reversible with noninvasive airway maneuvers, and oxygen saturation (SpO2) values with supplemental oxygen may be an important factor in considering prehospital intubation.13 While no study has clearly defined a subgroup of head-injured patients who should undergo early intubation, neural network analysis using data from our trauma registry suggests that the most critically injured patients, as defined by GCS score and the presence of hypotension, benefit from the procedure. In addition, intubation does provide additional benefit with regard to the reversal of hypoxemia in some patients.3,13

Who Should Perform Prehospital RSI?

The San Diego Paramedic RSI Trial prospectively enrolled severe TBI patients who could not be intubated without medication. The primary outcome analyses compared trial patients with non-intubated historical controls matched for age, gender, mechanism, trauma center, and body region Abbreviated Injury Scores. Despite a substantial increase in the percentage of patients arriving with an invasive airway, trial patients had higher mortality and a lower incidence of good outcomes.14 Subsequent analyses suggest that suboptimal performance of the procedure, including hyperventilation and deep desaturations, accounts for at least part of the mortality increase.13 This may reflect the inexperience of paramedics in that system with regard to RSI and the limitations of a single, 8-hour training session.

Other systems providing more intensive training have documented improved success rates, although the link between experience and performance of RSI remains unclear.15 In the San Diego study, the only subgroup with improved outcomes versus matched historical controls was the group undergoing RSI by paramedics then transported by air medical crews.13,14 The low incidence of hyperventilation in this cohort may explain this somewhat unexpected finding. Subsequent analyses from San Diego and from Pennsylvania document worse outcomes with paramedic intubation but improved outcomes with air medical RSI as compared to emergent intubation in the ED.8,16 Together, these studies suggest that prehospital RSI may be efficacious when performed by experienced, highly trained individuals. The extent and frequency of initial and ongoing training remains to be defined.

FINAL COMMENTS

Prehospital airway management is a difficult task that requires training and skills. Endotracheal intubation remains the gold standard of airway management. Specific strategies need to be in place for basic and advanced units (Figures 5 and 6). Higher success rates will be achieved if endotracheal intubation is attempted after the use of rapid sequence analgesia and paralysis; however, most ground units are not prepared and are not allowed to use such strategy. On the other hand, most aeromedical transport units are facile with RSI and employ this strategy with marked success. A successful RSI program requires medical direction and supervision, training and continuing education, resources for patient monitoring, drug storage and delivery, conformation and monitoring of endotracheal tube placement, standardized protocols, back-up airway methods, and continuing quality assurance and performance review.20

REFERENCES

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