44 Pharmacology – 2
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| 1. The use of ethanol in methanol poisoning is an example of competitive agonism. |  |
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| 2. Compliance therapy has been shown to improve the outcome in patients prescribed neuroleptic medication. |  |
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| 3. Zero-order kinetics can be correctly described in terms of half-life. |  |
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| 4. Heteroceptors regulate neurotransmitter release. |  |
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| 5. Heteroceptors can be ionotropic or metabotropic. |  |
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| 6. Acetylcholine is a transmitter at some postganglionic sympathetic neuroeffector junctions. |  |
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| 7. Muscarinic receptors are coupled to ion channels. |  |
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| 8. Pregabalin binds to the alpha 2 delta subunit of voltage-sensitive calcium channels. |  |
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| 9. DHEA has an effect opposite to that of cortisol. |  |
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| 10. Benzhexol inhibits dopamine secretion. |  |
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| 11. The firing rate of neurons in the mesolimbic pathway changes in anticipation of pleasurable stimuli. |  |
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| 12. Dopamine receptors are postsynaptic but not presynaptic. |  |
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| 13. Raclopride is used to study dopamine receptor binding. |  |
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| 14. Opiates regulate dopamine activity. |  |
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| 15. Glutamate concentration is increased in post-mortems of schizophrenic brains. |  |
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| 16. Magnesium ions block NMDA receptors. |  |
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| 17. Nicotine reaches the brain within 5–6 seconds after inhalation. |  |
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| 18. Nicotine increases the brain dopamine in the mesolimbic region. |  |
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| 19. The NMDA receptor is a voltage gated channel. |  |
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| 20. β-adrenergic receptors are stimulatory. |  |
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| 21. The upper limit for a normal QT interval is approximately 400 ms. |  |
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| 22. Increased 5-HT in the periaqueductal grey matter increases the fright/flight response. |  |
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| 23. Serotonin transporter gene polymorphisms are associated with violence. |  |
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| 24. In neuroimaging, iodobenzamide may be used as a ligand for 5-HT2A receptors. |
