Perirectal Abscess and Fistula in Ano

Published on 16/04/2015 by admin

Filed under Surgery

Last modified 22/04/2025

Print this page

rate 1 star rate 2 star rate 3 star rate 4 star rate 5 star
Your rating: none, Average: 1 (1 votes)

This article have been viewed 18109 times

Chapter 27

Perirectal Abscess and Fistula in Ano

Perirectal Abscess

Anatomic Description

Anorectal abscess are defined by their anatomic relationship to the internal and external sphincter and levator musculature (Fig. 27-1). Abscesses that remain localized to the body of the gland in the potential intersphincteric space, between internal and external sphincters, are termed intersphincteric abscesses. Abscesses that perforate laterally through the external sphincter into the lower extrarectal space are called ischiorectal abscesses. The ischiorectal space is a pyramidal area bordered by the rectum and anus medially and pelvic side wall laterally. The apex of the ischiorectal space is formed by the levator ani muscle, and posteriorly the sacrotuberous ligament and gluteus maximus muscle form its borders. Importantly, the pudendal and internal pudendal vessels run through the superolateral wall of the ischiorectal space.

Most often, the infection will track through the intersphincteric space into the base of the ischiorectal space and into perianal soft tissue. This is termed a simple perirectal (perianal) abscess (PRA). This space contains both the external hemorrhoidal plexus and the subcutaneous part of the external anal sphincter.

Rarely, the infection will track cephalad and is termed supralevator abscess. More frequently, infections in the supralevator space originate in the pelvis, usually as a result of a diverticular abscess eroding through the pelvic floor. This space is bordered inferiorly by the muscles of the levator ani, laterally by the obturator fascia, and medially by the rectum.

Surgical Management of Anorectal Abscess

The main issue in the management of PRA is control of sepsis by draining the abscess. Surgical management requires not only adequate drainage but also effective anesthesia, for perioperative management as well as early postoperative pain control. An appropriate perianal block must be administered at surgery and relies on blocking nociceptive impulses from the pudendal nerve bilaterally. This approach allows for maximal relaxation and also sphincter relaxation, which augments exposure.

A perianal block is administered by injection of local anesthetic at the root of the pudendal nerve as it exits from Alcock’s canal just medial to the pubic tubercle (Fig. 27-2, A). The tubercle is easily palpated through the skin, and the needle is introduced medial to this, as deeply as possible. Additional local anesthetic is fanned out in a diamond shape adjacent to the sphincters, to infiltrate the ramifying branches of the nerve. Another option is to perform a ring block, in which local anesthetic is introduced into the perianal skin and the underlying sphincter muscle.

Lastly, the skin immediately surrounding the abscess can be infiltrated. For all these methods, a small-bore needle (25 gauge) should be used because rapid infiltration through a large-bore needle can cause pain. Further, the acidic milieu that results from a purulent environment leads to less effective anesthesia if directly infiltrated; therefore the nonerythematous skin in the area should be targeted.

Specific Abscesses

Superficial anorectal abscesses are drained directly; the incision should be large enough to provide adequate drainage. Incisions should be made radially to avoid disruption of sensory and motor nerves.

Ischiorectal abscesses are deeper but they are approached in a manner similar to superficial abscesses. Whenever possible, these procedures should be done with the patient under anesthesia to allow for appropriate exposure and pain control. We routinely position the patient in the prone jackknife position, with buttock retraction using tape (Fig. 27-2, B). This position allows for optimal exposure for both surgeon and assistant. The incision should be large enough to allow for adequate drainage. Blunt dissection should be avoided to minimize damage to small nerves and blood vessels in the ischiorectal fossa. Packing of the abscess cavities is unnecessary and counterproductive to effective drainage and should be used only when needed to control hemorrhage.

The patient with intersphincteric abscess often shows no external stigmata of abscess. The patient will complain of severe pain, especially during defecation, and bedside examination is often prohibitively painful. In these cases, once the abscess is localized by needle aspiration, drainage through the wall of the rectum is indicated, with adequate division of the overlying internal sphincter musculature to allow for adequate drainage.

Supralevator abscesses should not be drained by the transanal approach and may require percutaneous drainage using interventional radiology, or appropriate operative control through a transrectal approach.

Deep Postanal Space

The deep postanal space abscess is a unique case that requires a high index of suspicion to identify. Chronic recurrent bilateral ischiorectal abscesses are called “horseshoe” abscesses and are pathognomonic for an abscess source in the deep postanal space. The deep postanal space is located cephalad to the anococcygeal ligament in the posterior midline and continues to bilateral ischiorectal spaces. Injection of either ischiorectal abscess cavity will usually result in drainage from an internal fistula in the posterior midline.

Effective management of these fistulas requires not only drainage through counterincisions over each ischiorectal space, but also unroofing of the deep postanal space. This approach requires division of the anococcygeal ligament and entry into this space (Fig. 27-3, A). The surgeon should work toward and just distal to the coccyx to guide the appropriate dissection. Division of the anococcygeal ligament and discharge of purulent fluid will confirm entry into this space.

If a fistula is encountered in the posterior midline, division of the internal sphincter musculature distal to the fistula and into the deep postanal space is performed to allow adequate drainage. Counterincisions over the ischiorectal abscess are performed, and drainage catheters or Penrose drains are passed through to facilitate decompression. In patients with recurrent fistula, wide division of the residual external sphincter may be required, termed the modified Hanley procedure.

Occasionally, deep ischiorectal fossa abscesses cannot be easily drained by superficial incisions. In these cases, drainage may be facilitated by placement of catheter with a mushroom or flared tip. This approach allows for continued drainage and development of a persistent tract, which will remain open after the catheter is removed (Fig. 27-3, B).

Fistula in Ano

Approximately 30% to 50% of anorectal abscesses will have associated fistulas. A fistula is defined as an epithelialized tract that connects two epithelially lined organs, in this case the rectum and the skin. This condition is usually heralded by chronic or recurrent drainage from a prior draining abscess site. Appropriate determination of the presence and anatomy of a fistula is imperative to guide treatment.

Anatomic Description

Types of Fistula

Fistulas are defined by their anatomic relationship to the pelvic floor musculature and sphincter complex (Fig. 27-4, A). The majority of fistulas track low through the subcutaneous soft tissue with minimal sphincteric involvement and are termed simple, or superficial. Simple lay-open fistulotomy is a time-honored and effective approach with a high success rate. Complex fistulas traverse a significant component of the sphincter or levator musculature and must be approached with caution. Performing a fistulotomy would require division of significant amount of sphincter muscle and may impair the continence mechanism.

Intersphincteric fistulas track through the intersphincteric space and exit on the perianal skin. Transsphincteric fistulas traverse both internal and external sphincter muscles. Extrasphincteric fistulas track above the sphincter complex from an internal opening and exit superficially, whereas suprasphincteric fistulas originate above the muscular pelvic diaphragm and exit externally.

The relationship of the external opening to the anal verge can offer clues as to the source of the internal opening using Goodsall’s rule: An imaginary line is drawn transversely across the anal opening, and fistulas anterior to this line generally track radially to internal rectal openings (Fig. 27-4, B). Fistulas posterior to this line, as well as those located greater than 2 cm from the verge, tend to originate from a posterior midline opening.

Surgical Management of Anorectal Fistula

Complex fistulas are treated initially by management of local sepsis through adequate abscess drainage. To spare sphincter musculature, a draining seton is usually the initial step in management. Draining setons are biologically inert drains through the fistula tract to provide ease of egress of infected material (Fig. 27-5, B).

Once sepsis and inflammation have resolved, the anatomy of the fistula and its relationship to the sphincter musculature can be better defined, either by careful clinical examination or adjunctive imaging studies such as ultrasound or pelvic MRI.

Intersphincteric fistulas can usually be safely approached with fistulotomy. Division of part or all of the internal sphincter muscle can usually be accomplished with little to no change in continence. This procedure is most easily done by placing a fistula probe through the fistula and dividing along it with electrocautery.

Special consideration must be given to female patients, especially those of reproductive age and with anterior fistulas, because the sphincter complex is usually thinner and more tenuous anteriorly. In addition, the rate of occult sphincter injury after vaginal delivery is significant, approaching 30%, and further compromise of the sphincter musculature may result in changes of continence in a previously asymptomatic female.

It can be difficult at times to differentiate between the internal and external sphincter. One helpful surgical maneuver is to place the sphincter mechanism on gentle stretch with an operating anoscope and use the back of a dissecting forceps or finger to feel the groove between the internal and external sphincter. In doing this, surgeons can be reassured as to whether they are dealing with an intersphincteric or a transsphincteric fistula. Additionally, only fibers of the voluntary external sphincter will twitch when stimulated by electrocautery. The involuntary internal sphincter should not react to electrocautery.

Transsphincteric fistulas are best treated conservatively with sphincter-sparing approaches. Many techniques have been developed for their management. Initial approaches should include sphincter-sparing techniques, such as injection of fibrin glue along the fistula tract to seal the fistula and promote healthy tissue ingrowth. This approach is safe and has not been shown to affect continence; however, success rates are uniformly poor, often less than 20%, and require expensive materials.

The fistula plug is currently the most widely used approach and involves pulling a tapered plug of porcine submucosa or fibrous scaffolding through the fistula tract and anchoring it to the sphincter muscle. Initial reports of success with this approach were encouraging, with success rates as high as 80%. However, time and experience have shown durable results to be much lower in general, with success rates in the range of 30% to 40%. In addition, the plugs are expensive and often not covered by insurance.

More recently, the development of the LIFT—ligation of the intersphincteric fistula tract—procedure has been used with significant success. This technique involves isolating the fistula tract as it traverses the intersphincteric space, ligating it, and excising the intersphincteric component. Preliminary results show it to be comparable or even superior to the fistula plug, with a similar safety profile. This technique is easy to perform and becoming more widely used, with a randomized clinical trial of LIFT versus fistula plug underway.

Persistent failure or extrasphincteric fistulas may also be approached with the advancement flap. This technique is more difficult and involves mobilization of a full-thickness or partial-thickness flap of anoderm (endoanal) or rectal wall (endorectal). After excising the internal opening and scarred mucosa, the surgeon sutures a flap over the internal fistulous opening. This technique is more technically demanding, requires significant experience and training, puts large sections of otherwise healthy tissue at risk for ischemia and tissue loss, and can result in larger internal defects. Also, these dissections are associated with a not-insignificant risk of changes in continence because of the dissection of internal and external sphincters.

Suprasphincteric fistulas often arise from a pelvic source, usually a diverticular abscess. Appropriate source control and management of the source will usually result in closure of the fistula.

Occasionally, complex fistulas remain refractory to sphincter-sparing approaches. Strong consideration must be given to maintenance of a long-term indwelling seton to minimize the risk of recurrent sepsis and avoid the risk of significant impairment in continence.

Crohn-Related Abscess and Fistula

Complex perianal abscesses and fistulas are a hallmark of anorectal Crohn disease. As with benign anorectal abscesses, treatment requires initial management of local sepsis, with drainage and minimal dissection, because healing is impaired in patients with inflammatory bowel disease (IBD). Once local sepsis is managed, appropriate medical therapy can be initiated. The use of biologic modifiers (e.g., anti-tumor necrosis factor therapy) has been shown to have significant efficacy in healing anorectal fistulas, and thus surgery may not be necessary.

Unlike benign cryptoglandular fistulas, Crohn-related fistulas are often complex with multiple blind-end tracts. In general, they do not follow Goodsall’s rule (see earlier). Because of the issues related to recurrence and difficulty with healing, typical surgical approaches are associated with high morbidity and chronic wounds that may not heal.

In the patient with quiescent disease and superficial fistulas, fistulotomy has been shown to be effective. With medically controlled disease and transsphincteric fistulas, sphincter-sparing approaches (e.g., fistula plug, fibrin glue) may have some success. Often, chronic use of indwelling setons is indicated to avoid significant morbidity and risk of sphincter injury associated with repair attempts. Patients with Crohn-related abscess and fistula should be referred to specialists who often see patients with Crohn disease.

Suggested Readings

Abbas, MA, Lemus-Rangel, R, Hamadani, A. Long-term outcome of endorectal advancement flap for complex anorectal fistulae. Am Surg. 2008;74:921–924.

Bleier, JI, Moloo, H, Goldberg, SM. Ligation of the intersphincteric fistula tract: an effective new technique for complex fistulas. Dis Colon Rectum. 2010;53:43–46.

Champagne, BJ, O’Connor, LM, Ferguson, M, et al. Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up. Dis Colon Rectum. 2006;49:1817–1821.

Christoforidis, D, Pieh, MC, Madoff, RD, Mellgren, AF. Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study. Dis Colon Rectum. 2009;52:18–22.

Dudding, TC, Vaizey, CJ, Kamm, MA. Obstetric anal sphincter injury: incidence, risk factors, and management. Ann Surg. 2008;247:224–237.

Garcia-Aguilar, J, Belmonte, C, Wong, WD, Goldberg, SM, Madoff, RD. Anal fistula surgery: factors associated with recurrence and incontinence. Dis Colon Rectum. 1996;39:723–729.

Hanley, PH. Conservative surgical correction of horseshoe abscess and fistula. Dis Colon Rectum. 1965;8:364–368.

Johnson, JK, Lindow, SW, Duthie, GS. The prevalence of occult obstetric anal sphincter injury following childbirth: literature review. J Matern Fetal Neonatal Med. 2007;20:547–554.

Lewis, RT, Maron, DJ. Anorectal Crohn’s disease. Surg Clin North Am. 2010;90:83–97.

Lindsey, I, Smilgin-Humphreys, MM, Cunningham, C, Mortensen, NJ, George, BD. A randomized, controlled trial of fibrin glue vs. conventional treatment for anal fistula. Dis Colon Rectum. 2002;45:1608–1615.

Malik, AI, Nelson, RL. Surgical management of anal fistulae: a systematic review. Colorectal Dis. 2008;10:420–430.

Rojanasakul, A, Pattanaarun, J, Sahakitrungruang, C, Tantiphlachiva, K. Total anal sphincter saving technique for fistula-in-ano: the ligation of intersphincteric fistula tract. J Med Assoc Thai. 2007;90:581–586.

Swinscoe, MT, Ventakasubramaniam, AK, Jayne, DG. Fibrin glue for fistula-in-ano: the evidence reviewed. Tech Coloproctol. 2005;9:89–94.