Normal pregnancy and antenatal care
Aims and patterns of routine antenatal care
The basic aims of antenatal care are:
• To ensure optimal health of the mother throughout pregnancy and in the puerperium.
• To detect and treat disorders arising during pregnancy that relate to the welfare of both the mother and the fetus and to ensure that the pregnancy results in a healthy mother and a healthy infant.
The ways by which these objectives are achieved will vary according to the initial health and history of the mother and are a combination of screening tests, educational and emotional support and monitoring of fetal growth and maternal health throughout the pregnancy.
The risk of substance abuse in pregnancy
Smoking
Smoking has an adverse effect on fetal growth and development and is therefore contraindicated in pregnancy. The mechanisms for these effects are as follows (Fig. 7.1):
• The effect of carbon monoxide on the fetus. Carbon monoxide has an affinity for haemoglobin 200 times greater than oxygen. Fresh air contains up to 0.5 ppm of carbon monoxide, but in cigarette smoke values as high as 60 000 ppm may be detected. Carbon monoxide shifts the oxygen dissociation curve to the left in both fetal and maternal haemoglobin. Maternal carbon monoxide saturation may rise to 8% in the mother and 7% in the fetus, so that there is specific interference with oxygen transfer.
• The effect of nicotine on the uteroplacental vasculature as a vasoconstrictor. Animal studies on the effect of infusions of nicotine on cardiac output have shown that high-dose infusions produce a fall in cardiac output and uteroplacental blood flow. However, at levels up to five times greater than those seen in smokers there are no measurable effects and it is therefore unlikely that nicotine exerts any adverse effects by reducing uteroplacental blood flow.
• The effect of smoking on placental structure. Some changes are seen in the placental morphology. The trophoblastic basement membrane shows irregular thickening and some of the fetal capillaries show reduced calibre. These changes are not consistent or gross and are not associated with any gross reduction in placental size. The morphological changes have not been demonstrated in those women subjected to passive smoking.
• The effect on perinatal mortality. Smoking during pregnancy reduces the birth weight of the infant and also reduces the crown–heel length. Perinatal mortality is increased as a direct effect of smoking and this risk has been quantified at 20% for those women who smoke up to 20 cigarettes per day and 35% in excess of one packet per day. Mothers should be advised to stop smoking during pregnancy.
The booking visit
The details of antenatal history and routine clinical examinations are discussed in Chapter 6. However, certain observations should be stressed at the first visit and it is preferable that these observations should be made within the first 10 weeks of pregnancy. The measurement of maternal height and weight is important and has value in prediction of pregnancy outcomes. Women with a low body mass index (BMI; less than 20, where BMI is estimated as weight (kg) divided by height (m2)) are at increased risk of fetal growth restriction and perinatal mortality. Women with a high BMI are increasingly recognized as being at increased antenatal and intrapartum risk, with the risks beginning to rise from a BMI of 30.