Myeloproliferative neoplasms

Published on 04/03/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 04/03/2015

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17 Myeloproliferative neoplasms

Myeloproliferative neoplasms are clonal hematopoietic stem cell diseases with expansion, excessive production, and overaccumulation of erythrocytes, granulocytes, and platelets individually or in some combination.

The World Health Organization classification of tumors of the hematopoietic and lymphoid tissues has divided these disorders into four major categories:

These neoplasms have common clinical features, laboratory findings, and pathogenetic similarities (Table 17-1).

Leukocyte alkaline phosphatase

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