Molecular Tools in Cancer Research

Published on 04/03/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 04/03/2015

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Chapter 1

Molecular Tools in Cancer Research

Summary of Key Points

• Our understanding and treatment of cancer have always relied heavily on parallel developments in biological research. Molecular biology provides the basic tools to study genes involved with cancer growth patterns and tumor suppression. An advanced understanding of the molecular processes governing cell growth and differentiation has revolutionized the diagnosis and prognosis of malignant disorders.

• This introductory chapter relates basic principles of molecular biology to emerging perspectives on the origin and progression of cancer and explains newly developed laboratory techniques, including whole genome analysis, expression profiling, and refined genetic manipulation in animal models, thus providing the conceptual and technical background necessary to grasp the central principles and new methods of current cancer research.