Inclusions in erythrocytes

Published on 04/03/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 04/03/2015

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12 Inclusions in erythrocytes

TABLE 12-1 Staining Qualities of Erythrocyte Inclusion Bodies

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Howell-jolly bodies

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FIGURE 12–1 Howell-Jolly bodies.

Color:

Dark blue to purple

Shape:

Round to oval

Size:

0.5-1.5 μm

Number per cell:

Usually 1; may be multiple

Composition:

DNA

Associated with:

Splenectomy, hyposplenism, megaloblastic anemia, hemolytic anemia

Basophilic stippling

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FIGURE 12–2A Basophilic stippling.

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FIGURE 12–2B Basophilic stippling.

Color:

Dark blue to purple

Shape:

Fine or coarse punctate granules

Number per cell:

Numerous with fairly even distribution

Composition:

RNA

Associated with:

Lead intoxication, thalassemia, abnormal heme synthesis

Pappenheimer bodies

Siderotic granules

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