Implantation of Intrathecal Drug Delivery Systems

Published on 10/03/2015 by admin

Filed under Neurosurgery

Last modified 10/03/2015

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Chapter 16 Implantation of Intrathecal Drug Delivery Systems

Opioids produce a profound inhibition of the evoked discharge of spinal nociceptive neurons, thereby inhibiting the transmission of pain. Intrathecally administered opioids have no effect on the motor function and autonomic responses. The analgesic effect of opioids is dose dependent and antagonized by naloxone.

Instrumentation

Equipment required for implantation of an intrathecal drug delivery system consists of the following:

Drugs needed for implantation of an intrathecal drug delivery system are as follows:

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Figure 16–10 Package of Highmol (20 mg/2 mL/ampoule)

(BC World Pharmacy Co., Ltd., Seoul, Korea).