How the cancer situation can be improved

Published on 09/04/2015 by admin

Filed under Hematology, Oncology and Palliative Medicine

Last modified 22/04/2025

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3 How the cancer situation can be improved

How to prevent cancer developing

Having identified the possible causations of cancer, we have an opportunity to use this knowledge to inform and influence individual lifestyles and behaviours. This can be done on several levels:

As healthcare professionals, we have a responsibility to promote and provide information to assist individuals to make healthy lifestyle choices, even if this is in a very small way. Many nurses working in acute care environments consider that their role is to care for ‘sick’ people and do not recognise the opportunities to improve the health of their patients and/or families. This needn’t be heavy handed – it might be during a routine admission or assessment. We often ask patients whether they smoke, but what do we do with this information? This is a good opportunity to gently enquire whether the individual has considered or has even tried to give up smoking. If they show interest we should either refer or signpost them to the local smoking cessation programme or provide information on the national telephone helpline/Website. We don’t need to have all the answers. It is about providing the information to direct people to existing services that can support them. If they are not interested in changing their behaviours, they will soon tell us. It is their choice how they live their lives and we have no right to judge them.

How survival rates can be improved

As well as preventing cancers in the first place, detecting cancers early in their development also reduces the risk of death. The majority of cancers are identified by individuals after they notice a change in their body appearance or function. When the sign or symptom has become noticeable, they seek medical advice. Unfortunately by this point the cancer has often become sizable and may have spread, making it difficult to treat, and the overall outcome may be less successful.

Early detection of cancer depends on people knowing what to look for and seeking prompt advice from their doctor (Box 3.1). Education is essential for people to understand how the body works; knowing what is normal for our own bodies helps us detect when something changes. Fear can play a large part in delaying seeking help and is often driven by ‘I don’t want to know’ or ‘they won’t be able to do anything for me’. These feelings may be based on previous family experiences or out-of-date information. It is important to educate people that cancer can often be treated and have a good outcome if it is detected and treated early, emphasising that it is vitally important to note any changes in body function or appearance.

Screening

A possible way of detecting a cancer before symptoms develop is through screening. The primary aim of screening is to identify a cancer at an early stage, so that treatment can be prompt and the impact of treatment may be minimised and more successful, although this is not always the case. The general population are targeted for screening, although programmes select specific age groups or high-risk individuals.

Wilson and Junger (1968) developed 10 principles (for the World Health Organisation) that should govern a national screening programme:

image Reflection point

Consider Wilson and Junger’s (1968) (see References) 10 principles of screening. Why do we have a breast screening programme and not a prostate screening programme?

NMC Domain 1: 1.4

NMC Domain 2: 2.6

NMC Domain 3: 3.5

Cervical screening

Cervical screening is fairly unique in the fact that it does not just detect cancer at an earlier stage but it can prevent cancer developing. This is because there is a recognised pre-cancerous stage called carcinoma in situ (CIN). If untreated, this condition will almost definitely develop into a cancer. However, if this is detected during screening then the affected tissues can be removed and the individual does not develop cancer. It is estimated that screening, the detection of CIN and prompt treatment can prevent 75% of cervical cancers.

The programme screens women between the ages of 25 to 49 every 3 years and 50 to 64 every 5 years. Women over 65 years who have not been screened since age 50 or have had an abnormal result can request screening. In 2005, the method of screening was changed to liquid-based cytology (involves brushing the cervix and suspending the brush in a medium before it is reviewed) to increase the reliability of the test.

The evidence in favour of screening for cancer of the cervix is convincing. Of the 4 million women in the UK invited for screening in 2007–2008, 3.3 million were tested and 93% were negative (NHS Cervical Screening Programme Statistical Bulletin (England 2009–10)).

Although commenced in the mid 1960s, the number of women attending cervical cancer screening has been sporadic and the number has declined slightly in the past 10 years. Of those women invited for screening, 78.9% attended. Women in the younger age groups have declined more rapidly.

Breast screening

The UK NHS Breast Screening Programme (1986) was the first of its kind in the world and national coverage was achieved by the mid 1990s. There have been numerous adjustments to the programme since this time. Currently all women aged 47 to 73 years are sent a letter inviting them to attend for a mammography every 3 years. Women over 73 can request screening.

In 2007–2008, of the 2.5 million women invited for screening, a total of 2 million were screened and 16   449 cancers were detected (Cancer Research UK 2010). Breast screening is well established and shown to be effective, lowering mortality rates (55–69 years) and saving approximately 1250 lives per year.

Colorectal screening

Colorectal cancer is often diagnosed very late, when the cancer has become inoperable and may have spread. This is because there are very few early signs or symptoms due to the amount of space in the abdomen. For this reason, the early detection of colorectal cancer through screening is very attractive. Colorectal cancer screening was introduced in the UK in 2008 for 60–69-year-olds and is due to be extended to 70–79-year-olds in the near future. Individuals receive a screening kit in the post asking them to provide a small sample of faeces which is then returned in the post to investigate the presence of faecal occult blood (FOB). In the event of a positive result, the individual will be recalled for a colonoscopy.

The bowel screening pilot study suggests that death rates can be reduced by 15–20% and it is estimated that by 2025 the screening programme could save more than 2000 lives every year. The use of flexible sigmoidoscopy as a screening tool has been shown in trials to be promising and may be introduced in the future.

Overall, it is often challenging to get people to attend screening, due to a lack of understanding of the programme or the test itself, logistical difficulties such as transport, child care, getting time of work, etc., or the fear of diagnosis (ignorance is bliss).

Although most people attending understand that screening involves a test to identify physical changes that might be a result of cancer, they also attend so they can feel reassured that they do not have cancer. If they are recalled for further investigation, it may be a complete surprise as they may not have any signs or symptoms.

No test is perfect and all screening methods will result in a number of ‘false negatives’. This is where an individual is told they are all clear but in fact they do have a cancer that has not been detected. Conversely, there are a number of false positives, where individuals are recalled for further investigation but do not have cancer. This can be psychologically distressing before the true results are reported.

There is a common misconception that screening is a diagnostic tool, but an individual cannot be diagnosed without a number of additional investigations, in particular a pathological sample.