History and Principles of Pain Rehabilitation

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CHAPTER 110 History and Principles of Pain Rehabilitation

INTRODUCTION

Pain rehabilitation is a specific form of rehabilitation medicine applied to the management of chronic pain. To qualify, it is important to distinguish between acute and chronic pain. Acute pain is a self-limiting form of noxious stimulation following tissue injury that persists during that period of time during which the body would be expected to repair itself and recover to its preexistent biological status. Chronic pain is a condition which lasts beyond the reparative phase. Secondary physical and behavioral effects develop that create disability and an inability to function. A variety of adverse events tend to be associated with the development of chronic pain including drug abuse, further decreased function, psychiatric abnormalities, multiple unsuccessful surgical interventions, social and economic isolation, and even suicide.1

Through the early 1970s, the primary medical discipline responsible for the treatment of intractable chronic pain fell mainly to neurosurgeons. Their singular focus entailed the performance of complex ablative surgical procedures to destroy neural pain transmission systems. Anesthesiologists complemented this treatment approach with an assortment of nerve blocks. Ultimately, this paradigm failed to produce successful long-term results. As well, the associated side effects and risks of the procedures were often too adverse to justify their routine use. These failures amplified the crux of the problem which was that no single discipline could manage the multifaceted nature of the problem. Recognition of these issues led to the development of an interdisciplinary approach in 1973–1974 by Bonica and associates at the University of Washington in Seattle, and a multidisciplinary approach by Rosomoff and colleagues in Florida at the University of Miami. Soon afterwards, pain societies were founded and pain medicine evolved, accompanied by the growing science of pain and its clinical applications. The road was difficult, because insurers and governmental agencies were reluctant to pay for treatment regimens or evolving techniques which were then too neophytic to have accumulated the data to support medical necessity. More than a decade passed until Medicare, in 1988, published its Appendix §35-21.1, Coverages Issues – Medical Procedures of Pain Rehabilitation, which set the first standard and, ultimately, criteria which other payors would use for reimbursement.

Unfortunately, surgical disciplines confounded this approach by developing more complicated operative remedies for which success was claimed, but whose supportive data base was questionable. The burgeoning world of anesthesiologic interventional techniques also claimed success, again unsupported by scientifically reliable data. The rehabilitation model appears to have produced the most acceptable data and, at least, has equal or better outcome results without the risks attending all interventional applications.2

THE NEUROPHYSIOLOGICAL BASIS OF PAIN REHABILITATION

In principle, pain is a signal received by the central nervous system from an anatomical, physiological, or pathological source producing a noxious impulse. Correction and restoration of function will result in diminution and cessation of pain perception.

Pain rehabilitation enables patients with chronic pain to return to a productive lifestyle. Pain centers or clinics are facilities where patients are sent for the treatment of chronic pain, after conventional management has failed and no further directed disease-oriented care is deemed appropriate.3

Patients who are considered candidates for pain rehabilitation have chronic pain, illness, disability conviction, and are physically and functionally impaired. Pathological abnormalities must be distinguished from dysfunction. Activation must occur before pain is resolved.4,5

Functional restoration is a keystone to pain rehabilitation. It must be multidisciplinary as compared to single treatments or exercises. Stretching, strengthening, physical modalities, aerobic activities, resistive exercises, education, conditioning, mobilization, pacing, biofeedback, relaxation, and other components are included as treatment individually and in combination. Although a pain rehabilitation program is designed for individuals with measurable functional deficit, it may also be appropriate for either the physically active individual or for someone with severe disability where optimization of residual capacities is needed.

Patients with chronic pain present a clinical challenge because of the vast time and the diagnostic and therapeutic resources they consume. The pain management approach must be capable of properly identifying patients’ problems whether sensory, perceptual, psychological, psychosocial, environmental, or biomechanical in nature. Treatment goals are to reduce chronicity, prevent re-injury or disability, and restore function, as well as to return the patient to a productive lifestyle.6

The original concept that nerve root compression from a herniated disc produces pain was challenged decades ago when Rosomoff7 presented a series of observations together with clinical and experimental evidence that supported the contention that alternative nonsurgical methods will provide successful treatment even for manifest disc herniations or lumbar stenosis. Physiologic studies demonstrated that, except for a transient painful impulse when the nerve is first impacted, sustained nerve root compression or ‘pinching’ does not produce pain.8 There could be numbness or loss of function, but this is not a painful event.

From inspection of human anatomy, it is inescapably clear that all low back injuries must have associated soft tissue abnormalities. Even if the forces causing the injury reach sufficient magnitude to herniate or rupture an intervertebral disc, the force must be transmitted first through the surrounding soft tissue that binds the spine together as a functional unit. These tissues, when injured, undergo a breakdown of the cell membranes to arachidonic acid, from which biosynthesis of prostaglandins and associated products ensues. One important issue in this process is the induction of a state of hyperalgesia, following which a pain signal will evolve when excessive mechanical stimulation occurs or when compounds of reaction to injury, such as histamine or bradykinin, are produced.9 The nerve itself does not originate the pain signal; nociceptors are stimulated to initiate the transmission of the signal.

It is our thesis that the disordered musculoskeletal system is responsible for initiating these phenomena.3,7,10 These structures are in the surrounding paraspinal muscles, buttocks, hips, and legs. These peripheral sites are treatable by alternative medical approaches. Treatment will restore function and alleviate pain, often without the need for correcting intraspinal abnormalities that have traditionally been designated as the pain generator. Further, a study carried out in 45 000 patients with low back pain indicated that only 1 in 200 of patients may actually need surgical intervention;11 in our experience the number of patients is 1 in 500.

Muscular and fascial abnormalities are called myofascial syndromes. They have been well described by Travell and Simons.12 Abnormal movements of the back, restricted ranges of motion in the hips or legs, or the presence of muscle tenderness and/or trigger points, are seen with myofascial syndromes. These can perpetuate mechanical dysfunction, continued strain, muscle fatigue, and pain.

ALGORITHM FOR PAIN REHABILITATION

Although it can be described in discrete phases, rehabilitation is a continuous process of evaluation, treatment, conditioning, and reevaluations. The intensity and duration of each process depends on a variety of parameters including patient’s response, rate of progress, the presence of comorbidities, and the number and type of objectives to be met. The algorithm is depicted in Figure 110.1 and the elements are described below.

Admission criteria

To enter the system, the patient undergoes evaluation over a 3-day period. The rehabilitation team attempts to identify the medical, behavioral, vocational, financial, social, and other significant problems. The approach is comprehensive and holistic. Patient selection criteria are broad. The patient must have the ability to understand and carry out instructions, must be compliant and cooperative, and must not have aggressive or disruptive behavior that would disturb the milieu. Patients with schizophrenia, manic-depression, or other major psychiatric disorders are not precluded as long as they are receiving treatment which renders them stable. The patient, the family, and significant others, such as the lawyer, the employer, and the insurer must be accepting of vthe program. Worker compensation, liability cases, multiple surgeries, long histories of invalidism, or drug abuse are not exclusionary conditions. Although integral, the financial, legal, and administrative aspects of patient admission are beyond the scope of this chapter.

Upon entry, patients are oriented to the program and are made aware of rules, policies, and expectations. Evaluations and observations are made by the various disciplines in order to:

The multidisciplinary team consists of physicians, psychologists, occupational and physical therapists, massage therapists, ergonomists, nurses, vocational counselors, and biofeedback therapists. Assessment of the injured individual by these disciplines considers not just the injury history but also the patient’s physical and behavioral status and vocational issues, if applicable.

The outcome of the exhaustive assessment is a constructed, formalized care plan detailing problem areas, treatment strategies, and expected outcomes. Due to the large number of possible findings upon initial assessment, a set of ‘key indicators’ is used to monitor progress towards the final goals. Key indicators may include (1) pain level; (2) number of hours of sleep; (3) pain medications; (4) lifting, carrying, sitting, standing, walking tolerances; (5) ranges of motion of the neck and trunk; (6) straight leg raise; (7) composite hip range of motion; (8) posture; (9) strength; (10) gait; (11) and key behavioral and vocational problems. These indicators are updated on a weekly basis.

Phase I may take 2–3 days for interviews and/or evaluations. A team meeting is then held, findings are discussed, and team recommendations are presented to the Medical Director. In a multidisciplinary conference, the Medical Director discusses the findings with the patient and significant other. Team recommendations, clarification of medical concerns, and diagnosis are addressed. Patient questions, misconceptions, and expectations are also discussed. Admission to the program is contingent upon the patient’s full consent to participate in the process, including tapering from narcotics or other dependence-producing substances.

Activation and physical restoration

During this phase, treatment is initiated. A variety of therapeutic approaches are used to restore ranges of motion, resolve trigger points, taper off narcotic medications, and begin the process of education and relearning. Stretching, physical agent modalities, body mechanics training, and behavioral interventions are used to guide the patients through what is probably the most difficult phase of the program. Patients must surmount hurdles of fear, anger, mistrust, and past misconceptions about diagnosis in order to proceed with confidence and acceptance. Education includes topics such as myofascial pain syndrome, relaxation, stress management, and healthy lifestyles. Simultaneously, the patient’s medication is reviewed and a rigorous management program is initiated and monitored, including tapering from narcotics or other dependence-producing drugs. The use of ice and other modalities to alleviate pain are introduced.

A daily treatment schedule is designed to accommodate the various treatments and disciplines. A typical treatment schedule for one patient is shown in Table 110.1. The contents of each patient’s schedule vary on a daily basis depending on the stage (week) in treatment, level of activation, and progress.

Table 110.1 Typical daily treatment schedule

Patient name___________________
Time Activity
8:00–8:30 Movement therapy, warm up, low-impact aerobics
8:30–10:00 Physical therapy, stretching, modalities, back exercises, functional electrical stimulation, active exercises, gait training, flare-up procedures
10:00–11:30 Occupational therapy, body mechanics training, biofeedback, functional circuits, pacing, walking, climbing, lifting, carrying, pushing/pulling, reaching, safety, joint protection, ADL training
11:30–12:00 Psychological counseling, family counseling, stress management, breathing exercises, hypnosis, vocational counseling, vocational preparation, case management
12:00–1:00 Lunch break
1:00–1:30 Strength and cardiovascular training
1:30–2:00 Neuromuscular massage therapy
2:00–3:00 Occupational therapy, upper extremity activities exercises, educational activities, work simulation
3:00–4:00 Group activity, educational sessions
4:00 Evening activities, recreational activities

Treatment is provided on a daily basis including Saturdays. At nighttime, patients are assigned ‘homework’; i.e. evening self-paced exercises determined by the treating therapist and monitored by nursing staff.

A very effective tool in this phase is the concept of daily goals, final goal setting, and self-monitoring. Computerized modeling is used to determine optimal pathways a patient should follow during rehabilitation. The model utilizes statistical projection methods, which take into consideration the patient’s initial performance level and the desired goals.13 This nonlinear model derives its coefficients from retrospective data collected from over 1000 patients with chronic pain who successfully completed the 4-week rehabilitation and functional restoration program, and who have returned to a productive lifestyle. Once initial levels of performance have been measured and treatment goals have been determined, the daily goals are assigned to provide a personalized print-out of the expected ‘daily’ performance. The daily goals program provides daily increments for the patient’s therapeutic activities. The optimal progression print-out from initial tolerances to final goals is used by the patient and the treating staff to determine effects needed to achieve the desired daily performance throughout treatment.

On a weekly basis or sooner, if necessary, a team conference reviews the patient’s progress and level of participation; and the team determines if the program should be continued, modified, or terminated. Behavioral issues are addressed early. The patient must be in agreement with the treatment plan. The building blocks for the postdischarge maintenance program also start during this phase.

EVALUATION OF FUNCTIONAL DISABILITY

Objective measurements are utilized to determine physical condition, functional abilities, behavioral health, vocational parameters, and other patient attributes relevant to the rehabilitation process. Methods of measuring functional capacity fall under three main categories: (1) patient’s self-report of functional levels, which provides information about the perception of how much the patient believes he can or cannot do; (2) medical examination to provide an estimate of medical impairment; and (3) assessment of abilities or limitations producing quantifiable measures reflecting the level of performance, in comparison with performance levels of healthy subjects (e.g. norms) or the match to job/task demands.

Physician evaluation

The entry to evaluation and treatment is through the physician. The physician must obtain a detailed, accurate history. The mechanism of injury and the precise location of the pain at onset are critical. A neurologic examination evaluates reflexes, muscle strength, and sensory status to document the presence or absence of neurologic deficits.14 Although neurologic screening is essential, it is most often not significantly positive. In fact, only 1% of individuals have neurologic dysfunction which is reversible usually and, therefore, should not be considered as a pathological deficit. The soft tissue examination must be sophisticated and thorough.15 All musculoskeletal and myofascial abnormalities must be identified. This is particularly important, since myofascial syndromes may simulate neurological syndromes, particularly radiculopathies. The straight leg raising (SLR) test may produce leg pain considered to be indicative of irritated nerve roots, but this occurs even more regularly with myofascial syndromes. Contractures of the hip musculature, particularly the hip rotators, are common and disabling with standing or walking, so that restricted ranges of motion about the hips are not necessarily an indicator of articular disease. Palpable soft tissue tenderness by itself, again, is thought by some to be less specific or reliable, but, to reiterate, tender/trigger points and restricted ranges of motion are the hallmark of myofascial syndromes and must be sought so they can be identified and treated. They are, in fact, objective findings.

Simple laboratory tests, including blood count and erythrocyte sedimentation rate, are sufficiently inexpensive and efficacious for use as initial tests when there is suspicion of back-related pathology, such as tumor or infection. Lastly, special tests such as radiographs, imaging techniques, electrodiagnostics, thermography, and discography should be reviewed or recommended, if deemed necessary, but should be interpreted with extreme caution.10

Motor dysfunction evaluation

This is a method developed to identify and effectively treat ‘motor’ dysfunction in patients with chronic pain conditions.16 This innovative testing utilizes on-line computerized electromyographic (EMG) methods to study recruitment of muscles involved in a chain of motor activities.17 This method may detect functional muscular abnormalities that cannot be identified by clinical examination, even by experienced observers. The EMG signals of the various muscles are examined for baseline activity, symmetry, magnitude, frequency contents, synchrony, timing, and patterns. Patients’ behaviors are also observed. Motor dysfunction evaluation (MDE) findings are then compared to relevant clinical findings. Patient-specific, as well as condition-specific, multidisciplinary approaches are then generated to deal with the problems during daily treatment. The overall objective is to improve function and accelerate restoration. This is accomplished through using EMG and other electrically assisted methods to increase sensory perception of muscles and joints; increase neuromuscular recruitment; increase strength and endurance; and reestablish synchrony, symmetry, pattern, and synergy of muscle activity, thereby increasing functional capacities and reduction of pain.

Behavioral therapy/psychological evaluation

This examination reveals a great deal about the patient’s mental state, behaviors, coping styles, and the effects of pain or injury on personality. Behavioral analysis considers compliance, achievement level before injury, activity level after injury, functional capacities, anxiety, depression, personality disorders, marital status, role reversal, and family dysfunctional states. There are psychological tests designed to elicit responses which can be translated into numerical values and compared with the performance of other persons, such as the Minnesota Multiphasic Personality Inventory and the Millon Behavioral Health Inventory Assessment. These instruments test psychogenic attitudes, such as chronic tension, recent stress, premorbid pessimism, future despair, social alienation, and somatic anxiety. They are not a predictor of outcome, nor should they be used for that purpose. We no longer use these instruments, but depend heavily on individual interview assessments.18 If utilized, it should be for the purpose of finding out how the treating staff can interact with the individual in an effective manner to allow the patient to accept the rehabilitation plan. The patient has to be a partner in the rehabilitative process; otherwise, the effort will fail.

Psychological services offer biofeedback, relaxation training, coping skills training, assertiveness, stress management, and self-hypnosis. Group and family therapy deal with social interactions, return to environment, employment, and disability versus wellness with an emphasis on function, not pain. Psychological evaluations are tailored to document these issues. They work with the vocational counselors concerning return to work issues.