Oral vesicles of hand, foot, and mouth. There are painful, white, aphthae-like erosions on the tongue, lips, and hard palate. Eating can be painful.

Palmar and plantar vesicles appear cloudy with a small red halo. These lesions may be tender or asymptomatic. They may be sparse or numerous.

Typical vesicles of hand, foot, and mouth disease on the heel. Pain may impede walking, although generally this is a mild illness.