Chapter 3 Gastrointestinal system
Peptic ulcer
Case history
When you ask Dan about other symptoms he tells you he sometimes gets tension headaches, particularly if he’s had a busy week. He usually takes aspirin or ibuprofen, which work well for him. Apart from the stomach problems and occasional headaches Dan says he feels pretty good most of the time. He drinks 5–6 cups of coffee a day and more if things are particularly busy and he needs to keep going. He also often works through his lunch break and eats when he can, which is often on the run. Dan has noticed if he eats spicy foods he is more likely to experience the stomach problem, so
Analogy: Skin of the apple |
Analogy: Flesh of the apple | Context: Put the presenting complaint into context to understand the disease |
AREAS OF INVESTIGATION AND EXAMPLE QUESTIONS | CLIENT RESPONSES |
Cancer and heart disease | |
Do you experience indigestion that is usually only related to physical activity? (angina) | No. I can often feel it when I am lying still. |
Functional disease | |
So would you say your indigestion is not related to physical activity? (heartburn, oesophageal reflux) | I can get the pain when I am still or when I am moving but most often when I am not moving. |
Analogy: Core of the apple with the seed of ill health | Core: Holistic assessment to understand the client |
AREAS OF INVESTIGATION AND EXAMPLE QUESTIONS | CLIENT RESPONSES |
Daily activities | |
How often does the abdominal discomfort disturb you during the night? | If I don’t take the antacids I can be up most nights for a week and then it will settle down a bit. |
Action needed to heal | |
What do you think is important to do for your symptoms to clear up in the short term? | Coming today to see you to help with the stomach pain and stress levels. Maybe have more medical tests to find out what the pain actually is because it doesn’t seem to be going away in a hurry. |
TABLE 3.4 DAN’S SIGNS AND SYMPTOMS
he usually avoids it. Dan doesn’t drink alcohol during the week, but will relax on the weekends with a bottle or two of red wine.
Results of medical investigations
No medical investigations have been carried out yet.
TABLE 3.5 UNLIKELY DIAGNOSTIC CONSIDERATIONS [2, 7, 8, 10, 11, 54]
CONDITIONS AND CAUSES | WHY UNLIKELY |
---|---|
CANCER AND HEART DISEASE | |
Congestive heart failure | Blood pressure within normal limits; urinalysis NAD |
Cluster headaches: common to begin in males between the ages of 40 and 60; no family history associated with cluster headaches | Extremely severe headaches, stabbing and burning; usually unilateral and pain behind eye radiating to the front of the face |
INFECTION AND INFLAMMATION | |
Kidney infection | Abdominal pain usually is lower and will radiate to lower back and groin rather than upper abdomen and shoulder; no urine crystals and red blood cells |
Sinus headache: headache worse on waking in the morning | No upper respiratory symptoms mentioned, no frontal facial pain reported; need to check if dull ache is aggravated by bending |
ENDOCRINE/REPRODUCTIVE | |
Diabetes: delayed gastric emptying and complains of early fullness, nausea, bloating | Urinalysis NAD |
Case analysis
Not ruled out by tests/investigations already done [2, 7–11, 55, 57, 59, 61, 65] | ||
CONDITIONS AND CAUSES | WHY POSSIBLE | WHY UNLIKELY |
CANCER AND HEART DISEASE | ||
Angina: brought on by physical activity and emotion; will be relieved by nitroglycerin | Burning sensation in chest, fast pulse | Usually not related to eating or abdominal symptoms; acute onset of symptoms; pain relieved by lying down |
Gastric tumour: can have history of Helicobacter pylori (H. pylori) infection [67] | Pain relieved by food or antacids nausea; early satiety, weight loss, lack of appetite | May present with diarrhoea; no mention of blood or mucus in stools, abdominal distension or frequent vomiting; pain made worse or relieved by food |
OBSTRUCTION AND FOREIGN BODY | ||
Acute gallstone pancreatitis: pain in the abdomen that is radiating, nausea, decreased appetite; commonly caused by gallstones that block the pancreatic drainage; often associated with alcoholic binges | Pain in upper abdomen | Upper abdominal pain usually radiates to the lower back; usually associated with significant fever, nausea, vomiting and change in bowel motions; will usually have lower abdominal symptoms such as flatulence |
OCCUPATIONAL TOXINS AND HAZARDS | ||
Causal factor: Sick building syndrome |
Headaches worse after working several days in a row; new buildings recently constructed | No upper respiratory complaints or fatigue reported |
Causal factor: Eye strain |
Headaches will generally occur after several days at work | Unusual unless work requires close vision or eyeglasses are not appropriate |
FUNCTIONAL DISEASE | ||
Causal factor: Intestinal gas: from decreased motility and overgrowth of bacteria |
Indigestion | More common in the elderly, vague symptoms of abdominal discomfort; will have lower abdominal symptoms such as flatulence |
Causal factor: Gas entrapment: hepatic or splenic flexure syndrome |
Can have abdominal discomfort that is referred as chest pain | Made worse by bending over |
Causal factor: Duodenal loop distention |
Indigestion, nausea | Specific to right upper quadrant pain, or pain in the right shoulder |
Causal factor: Hiatus hernia |
Heartburn, indigestion when associated with oesophagitis | Heartburn is a rare symptom of hiatus hernia unless accompanied by oesophagitis |
Functional gastrointestinal disorder | Can have indigestion symptoms made worse by stress | No reports of diarrhoea alternating with constipation; symptoms would be vague and non-specific if a functional disorder; usually continuous pain with no significant weight loss; will have lower abdominal symptoms such as flatulence |
Heartburn: not usually related to physical activity, brought on by oesophageal spasm [53] | Burning sensation in the chest, felt when lying down, caffeine frequently causes symptoms; pain related to meals and made worse by lying down | Pain would be intermittent over several minutes and recur over long periods; pain would radiate to the neck, jaw, arms and back; pain would be felt after heavy meals and bending over; certain foods can cause and relieve heartburn |
Non-ulcer dyspepsia: may have H. pylori; pain or discomfort in the centre of the chest/upper abdomen [53, 56, 58] | Upper abdominal pain, feeling full quickly after eating, lack of appetite, nausea, belching, vomiting, bloating, burning sensation in chest or abdomen | No difficulty swallowing or vomiting mentioned by Dan; symptoms at night rare with non-ulcer dyspepsia; pain is usually worse after eating and not usually relieved by antacids with non-ulcer dyspepsia; diffuse abdominal pain is more common than precise location |
Reflux-dyspepsia Oesophageal reflux (gastro-oesophageal reflux disease, GORD; gastroesophageal reflux disease, GERD)/peptic oesophagitis/spasm: pain not brought on by exercise; may be precipitated by gastric juices, bile and duodenal juices and eating in general; treatment for H. pylori is not useful for reflux dyspepsia [64, 66]; more likely diagnosis if hiatus hernia present; it is possible to have symptoms of epigastric pain without heartburn and reflux in GORD/GERD [52, 55, 56] |
Tightness in chest, lack of appetite, becomes full quickly; common cause of heartburn symptoms that are relieved by antacids and made worse by lying down or bending over; will have chest pain; waterbrash symptoms signifies reflux; belching | In reflux, dyspepsia pain may radiate to the back, arms and neck; usually no nocturnal pain; can get nocturnal asthma and cough; common in pregnant women; chest and upper abdominal pain will be worse on stooping and after large meals; heartburn will be experienced more frequently than once every fortnight and acid regurgitation more than once a week; will have excess belching; possible to have overlapping condition with peptic ulcer; may have associated symptoms of asthma or chronic cough |
Dysmotility dyspepsia: caused by delayed gastric emptying rather than gastric hypersecretion; indigestion always brought on by eating; no H. pylori present [56] | Upper abdominal pain, nausea, early fullness, can be affected by stress; symptoms of heartburn reported | Symptoms often continuous, vomiting more than once every second month, hunger after feeling full quickly, heaviness after eating fatty foods or milk, bloating and distension in the abdomen; need to check if have any food intolerances |
Causal factor: Aerophagia |
Belching, heartburn symptoms, oesophageal reflux, functional GI disease | |
DEGENERATIVE AND DEFICIENCY | ||
Ulcer-like dyspepsia Peptic ulcer: gastric/stomach ulcer, duodenal ulcer, oesophageal ulcer; abdominal pain may be relieved by meals; can have overlapping symptoms of heartburn; will have H. pylori infection; risk factors are age 40 years and over, cigarette smoking, use of NSAIDs, family or past medical history of ulcer disease [56, 65] |
Can point to where burning epigastric pain is in the abdomen and show clearly where it is radiating to; gnawing pain; associated symptoms of nocturnal abdominal pain, nausea, decreased appetite, early satiety, weight loss; symptoms have periodicity like an ulcer and be pain-free for several weeks; can develop from chronic anxiety, tension; abdominal pain relieved by small amount of specific foods or antacids; vomiting can provide relief from pain; taking aspirin and ibuprofen for tension headaches; no significant reflux | May have vomiting on onset and previous history of ulcer disease; can have haematemesis (vomiting of blood); a common sign with a peptic ulcer is a fear to eat, but not with a duodenal ulcer; possibly has concurrent reflux dyspepsia with ulcer dyspepsia |
Cervical arthritis | Headache at the base of the head/neck area | No specific neck pain reported |
Anaemia: organic dyspepsia; pernicious anaemia (B12 deficiency) can cause indigestion and may develop from atropic gastritis and be linked to persistant infection with H. pylori bacteria in the stomach | Eating fewer meals, weight loss | Need to assess mineral absorption, variety of food groups, quantity of meals; usually associated with a long history of indigestion |
INFECTION AND INFLAMMATION | ||
Causal factor: H. pylori: improved by bismuth salts or antibiotics |
Causes bloating, pain in the stomach; involved in peptic ulcer disease, gastric tumour | Not in oesophageal reflux or dysmotility functional dyspepsia |
Gastritis: inflammation of stomach lining that can be made worse by aspirin, NSAIDs, corticosteroids, antibiotics, antiasthma agents; atropic gastritis from autoimmune destruction of parietal cells leading to lack of intrinsic factor and potentiating lack of B12 | Abdominal pain, indigestion, burning; loss of appetite, sense of fullness, nausea; vomiting can provide relief from pain; taking aspirin and ibuprofen for tension headaches | Pain will be worse after eating in gastritis; often associated with alcoholism; vague indigestion is more common in gastritis rather than specific location |
Giardia | Can present with upper abdominal symptoms such as nausea, bloating and persist for months | Symptoms will be persistent symptoms rather than episodic and may have diarrhoea |
Chronic appendicitis | Upper abdominal intermittent pain, nausea, vomiting on one occasion | No constipation or fever |
Cholecystitis: chronic and acute gall bladder inflammation | Symptoms can be vague gastrointestinal disturbance; biliary colic, right abdominal pain | The pain of gallstone colic/cholecystitis does not have periodicity like an ulcer; specific to right upper quadrant pain, or pain in right shoulder; will have lower abdominal symptoms such as flatulence |
Hepatitis | Pain in upper abdomen that is radiating; nausea; loss of appetite | No increased diarrhoea or lower abdominal symptoms mentioned |
Crohn’s disease | Abdominal pain; lesions can be from mouth to anus; weight loss, abdominal pain, low-grade fever and nausea; inflammation is deep and patchy | No blood or mucus in stools; no diarrhoea mentioned or recurrent episodes of watery bowel motions during day and night; no fever |
SUPPLEMENTS AND SIDE EFFECTS MEDICATION/DRUGS | ||
Causal factor: Drug ingestion: NSAIDs, antibiotics, potassium or iron supplements, alcohol, corticosteroids, theophylline derivatives, isoproterenol, anticholinergics |
Heartburn and indigestion, can cause H. pylori negative gastritis, lower esophageal pressure; taking aspirin and ibuprofen for his tension headaches increases the risk of developing a peptic ulcer | |
ENDOCRINE/REPRODUCTIVE | ||
Pancreatic disorders: chronic pancreatitis, vipoma (endocrine pancreatic tumour), Zollinger-Ellison syndrome | Symptoms of abdominal pain, episodes of pain, fatty diet; Zollinger-Ellison syndrome can present like a peptic ulcer (without H. pylori infection) with pain at night, nausea and lack of appetite | Symptoms of diarrhoea and steatorrhoea usually present; rare condition; will be from a long history of indigestion and often related to alcohol abuse |
STRESS AND NEUROLOGICAL DISEASE | ||
Migraine headache: severe painful headaches; often unilateral and located in the front and temporal regions of the head | Stress can exacerbate, can have indigestion and nausea as a complaint | Dan’s headaches not aggravated by or related to sound or light; migraine headaches usually improve upon waking and after sleep; no indication of nausea and vomiting associated with headache |
Causal factor: Stress [25, 26] |
Headaches, heartburn, indigestion | |
EATING HABITS AND ENERGY | ||
Causal factor: Food intolerance amine/salicylate sensitivity |
Headaches, drinking red wine, dairy; may be delayed sensitivity; salicylate sensitivity or overload can cause gastritis | Need to ask more regarding if the headaches are after eating particular foods that usually trigger migraine headaches |
Causal factor: Dehydration |
Lack of water in the diet, dull headaches, drinking excess tea and coffee, drinking alcohol |
TABLE 3.7 DECISION TABLE FOR REFERRAL [2, 7, 8, 10, 12]
Complaint | Context | Core |
---|---|---|
Referral for presenting complaint | Referral for all associated physical, dietary and lifestyle concerns | Referral for contributing emotional, mental, spiritual, metaphysical, lifestyle and constitutional factors |
REFERRAL FLAGS | REFERRAL FLAGS | REFERRAL FLAGS |
TABLE 3.8 FURTHER INVESTIGATIONS THAT MAY BE NECESSARY [2, 6–10, 11, 13, 54]
TEST/INVESTIGATION | REASON FOR TEST/INVESTIGATION |
---|---|
FIRST-LINE MEDICAL INVESTIGATIONS: | |
Abdominal inspection: guarding, rebound tenderness, palpation, abnormal pulsations (auscultation) | Signs of appendicitis, pancreatitis, kidney swelling, enlarged liver, bowel obstruction, perforated ulcer; positive Murphy’s sign for inflamed gall bladder; hiatus hernia signs, swallowed air; mid-epigastric tenderness in gastric and peptic ulcer |
Full blood count | Anaemia, inflammation, allergies |
C-urea breath test | H. pylori |
IgG antibodies | H. pylori |
When CRP is high it can indicate a bacterial infection | |
Stool test | Occult blood in stool may indicate ulcer or carcinoma, H. pylori |
IF NECESSARY: | |
Oesophageal motility studies | Cardiospasm, reflux oesophagitis |
Bernstein test (dilute hydrochloric acid in the distal oesophagus) | Produce symptoms of oesophagitis |
Oesophageal pH monitoring | Reflux oesophagitis GORD/GERD; may not determine oesophagitis |
Endoscopy [60, 62] | Confirmation of peptic ulcer, gastric tumour, non-ulcer dyspepsia; may not always define GORD/GERD or H. pylori |
GI radiographs | Oesophageal reflux, gas entrapment, gall bladder disease |
Gastroscopy | Gastritis |
Serum gastrin levels | To confirm or rule out Zollinger-Ellison syndrome and gastrinoma |
Serum amylase | Pancreatitis |
Small-bowel follow through | Exclusion or confirmation of Crohn’s disease |
Confirmed diagnosis
Dan and peptic ulcer
TABLE 3.9 DECISION TABLE FOR TREATMENT (ONCE DIAGNOSIS IS CONFIRMED)
• Recommendations to improve Dan’s diet and lifestyle
• Recommendations for Dan to exercise regularly
• Recommendation for Dan to take time out to eat his lunch slowly and in a quiet place
• Nutritional supplement recommendations to improve Dan’s general health and increase levels of essential nutrients
• Recommendation for Dan to review his work–home life balance and delegate or offload work where possible
• Recommendation for Dan to take up recreation activities outside of work to help reduce stress
• Recommendation for Dan to use stress-management techniques
• Herbal powder and tonic with adaptogenic, tonic and nervine action
• Herbal tea with nervine action
• Recommendation for a regular massage to reduce stress
• Nutritional supplement to help support Dan’s stress response
appetite and has lost weight recently. Dan says he is definitely burping more often and his symptoms can be worse when he is lying down at night. During the consultation Dan reveals that although he loves his job as a principal of a small school, he has experienced excessive stress with changes in procedures and staff as well as building renovations. He takes aspirin or ibuprofen regularly for tension headaches and has been drinking up to six cups of coffee a day and sometimes skips meals.
Peptic ulcers can be single or multiple open sores affecting the mucous membranes and are usually caused by failure of the digestive tract to withstand the action of pepsin and hydrochloric acid. This usually occurs because the mucous membranes become thinner, rather than as a result of excess pepsin or hydrochloric acid. A major cause of peptic ulcers is Helicobacter pylori (also known as Campylobacter pylori) infection [63]. Additional triggers include excess intake of NSAIDs, which results in thinning of the gastric mucosa and large dosages of pharmaceutical glucocorticosteroids. This influences the production of excessive quantities of pepsin, excessive long-term consumption of alcohol (ethanol) and the increased ingestion of the nicotinic acid form of vitamin B3 on an empty stomach releasing high levels of stomach acid. Stress has a significant impact on existing peptic ulcers and heartburn can be frequently experienced. Risk factors for developing a peptic ulcer are being over 40 years of age, cigarette smoking and family or past medical history of ulcer disease.
General references used in this diagnosis: 2, 6–11, 57, 59, 65
Treatment aims
• Reduce inflammation and promote healing of gastric mucosa [16, 17].
• Enhance integrity of gastric mucosa and gastroduodenal mucosal defence [16–18].
• Normalise gastric acid secretion [15, 18].
• Modulate Dan’s immune and inflammatory response [16].
• Support Dan’s stress response and help reduce his stress levels [16–18].
• Identify and reduce or eliminate contributing factors to Dan’s peptic ulcer [15, 18, 32].
• Determine whether Dan has any food allergies and manage accordingly [15, 18].
Lifestyle alterations/considerations
• Encourage Dan to reduce his stress levels [16–18, 25, 26]. He may find relaxation therapies such as meditation, yoga, tai chi or progressive muscle relaxation helpful to manage his stress levels.
• Encourage Dan to make the time to take a regular lunch break and eat his lunch slowly in a quiet and peaceful environment.
• Encourage Dan to find ways of reducing his work-related stress by reviewing his work schedule and workload. He may need to delegate tasks and/or enlist the help of others where necessary.
• Encourage Dan to take time away from work to enjoy other activities.
• Encourage Dan to exercise daily. Regular exercise is strongly associated with reduced stress levels [27, 28].
• Encourage Dan to stop taking aspirin or other non-steroidal anti-inflammatory medications. These are implicated in the development of peptic ulcers [15–18].
• If Dan smokes, he should stop [15–18].
• Dan may find that raising the head of his bed helps to alleviate symptoms during the night while he is in bed [10].
Dietary suggestions
• Food allergies should be tested for and managed appropriately [17, 18]. Milk should be avoided because it can significantly increase stomach-acid production [17, 18, 33].
• Fermented milk products, such as yoghurt containing live cultures of bifidobacteria and lactobacillus, may be helpful [16, 34, 35]; although, if Dan is allergic or intolerant to dairy products he should avoid them [17, 18].
• Encourage Dan to increase consumption of soluble fibre from fruit and vegetables [16–18].
• Encourage Dan to avoid foods that he knows aggravate his symptoms, and also avoid refined sugars [16, 17].
• Encourage Dan to avoid coffee, alcohol and chocolate [15].
• Encourage Dan to avoid spicy foods, spearmint, peppermint, fatty foods, carbonated beverages, orange juice and tomato juice [10].
• Cabbage and other cruciferous vegetables should be included in Dan’s diet every day [16–18]. The juice of half a head of cabbage or eating the cabbage raw may be beneficial during an acute episode [16, 18]. Cabbage can help prevent recurrence of ulcers [16] and has ulcer healing properties [17, 18].
• Encourage Dan to eat bananas every day. Bananas stimulate gastric mucosal cell growth and help maintain the protective layer on the gastric mucosa [17, 18]. Banana is also helpful to relieve acute symptoms of dyspepsia and heartburn [16].
• Ginger tea may reduce symptoms of dyspepsia [16, 18].
• One tablespoon of unpasteurised Manuka honey taken on an empty stomach at bedtime can relieve ulcers [16].
• Encourage Dan to increase his intake of foods rich in vitamin A. Vitamin A helps maintain the integrity of the mucosal barrier and protect gastric mucosa from damage [16, 17, 19, 22].
• Encourage Dan to reduce consumption of fatty foods and saturated fat [15, 16] and increase consumption of foods containing omega-3 fatty acids [16]. Olive oil is a good choice due to its antioxidant properties [16]. Diets high in olive oil are associated with a higher percentage of ulcer healing and reduced ulcerogenesis from NSAIDs [16].
• Encourage Dan to consume garlic and onions every day [18]. Garlic is effective against Helicobacter pylori [19]. If Dan’s reflux symptoms persist he may find avoiding garlic and onions reduces oesophageal pressure and therefore symptoms of reflux [10].
• Encourage Dan to take lecithin granules daily. The phosphatidylcholine in lecithin is gastroprotective [17, 44].
Physical treatment suggestions
• Dan may find massage therapy very helpful in reducing his stress levels and improve his ability to deal with stress [29, 30].
• A course of acupuncture therapy may be beneficial [31, 32].
• Hydrotherapy would be beneficial, such as dry skin brushing every day followed by a long, relaxing bath [49].
• Briefly tread in a cold foot bath followed by a hot compress to the abdomen, contrasted with a cold compress at the end [49].
• Taking neutral temperature baths for 30 minutes improves indigestion [49].
• Alternate brief hot and cold sitz baths [49].
• Constitutional hydrotherapy for toning of digestion and stress release [50, 51].
Alternative to coffee | ||
HERB | FORMULA | RATIONALE |
Chamomile flowers Matricaria recutita |
2 parts | Anti-inflammatory [16, 19, 20]; spasmolytic [16, 19, 20]; carminative [16, 19, 20]; antimicrobial [19, 20]; alpha-bisabolol in chamomile promotes tissue granulation and tissue regeneration in ulcers [19, 20, 36]; chamomile can prevent formation of ulcers [19, 36] and reduces healing time [19, 36]; anti-inflammatory action interrupts tissue destruction cycle and provides symptomatic relief [16] |
Ginger root powder Zingiber officinale |
½ part | Anti-nausea [19, 20]; anti-ulcer activity [19, 20]; anti-inflammatory [19, 20]; analgesic [19, 20]; inhibitory effect on H. pylori [19, 37] |
Lemon balm Melissa officinalis |
1 part | Anti-inflammatory [19]; analgesic [19]; antispasmodic [19, 21, 23]; antimicrobial [19, 23]; anxiolytic [19, 23]; sedative [19, 21, 23]; beneficial for gastrointestinal conditions associated with nervousness or anxiety [19, 21] |
Chickweed Stellaria media |
2 parts | Demulcent [19, 23]; antiulcer [23]; beneficial in gastric irritation [23] |
Infusion: 1 tsp per cup – 1 cup 3–4 times daily |
HERB | FORMULA | RATIONALE |
---|---|---|
Deglycyrrhizated licorice root powder [15, 18] Glycyrrhiza glabra |
1 part | Anti-inflammatory [19, 20]; mucoprotective [19, 20]; promotes mucosal repair and reduces symptoms of active ulcers [19, 20]; antimicrobial [19, 20]; anti-H. pylori properties [38]; adrenal tonic [20] |
Slippery elm bark powder Ulmus fulva |
1 part | Nutritive demulcent [19, 21]; emollient [19, 21]; traditionally used for inflammatory conditions of the gastrointestinal tract [19, 21] and for dyspepsia [19], gastric reflux [19] and peptic ulcers [19] |
Marshmallow root powder Althea officinalis |
1 part | Demulcent [21, 23]; emollient [21, 23]; vulnerary [21, 23] |
One heaped teaspoon mixed to a smooth paste with a little water 3 times daily before meals. Two heaped teaspoons in water can be taken as required to alleviate acute symptoms of heartburn. |
TABLE 3.12 HERBAL FORMULA (1:2 LIQUID EXTRACTS)
Made with ethanolic extract herbal liquids (alcohol removed) | ||
HERB | FORMULA | RATIONALE |
Meadowsweet Filipendula ulmaria |
70 mL | Anti-inflammatory [19, 23]; analgesic [19, 23]; gastroprotective [19, 23]; normalises stomach acid [16]; promotes healing of stomach ulcers [19, 39]; positive effect on antioxidant status of gastric tissue [40]; traditionally used for dyspepsia, heartburn and hyperacidity [21, 23] |
Golden seal Hydrastis canadensis (cultivated/plantation source) |
40 mL | Antimicrobial [19, 23]; mucous membrane trophorestorative [19, 23]; anti-inflammatory [19, 23]; vulnerary [19, 23]; bitter tonic [19, 23]; traditionally used for dyspepsia and gastritis [41]; beneficial for peptic ulcers [23]; inhibits growth of H. pylori [48] |
Siberian ginseng Eleutherococcus senticosus |
30 mL | Adaptogenic [19, 20]; immunomodulator [19, 20]; tonic [19, 20]; beneficial to improve stress response and increase energy levels [19, 20] |
Skullcap Scutellaria lateriflora |
30 mL | Nervine tonic [23]; spasmolytic [23]; mild sedative [21, 23]; traditional indications include nervous tension and anxiety [21, 23] |
Rhodiola Rhodiola rosea |
30 mL | Adaptogenic [42]; tonic [42]; traditionally used to treat fatigue, depression and nervous system disorders [42]; effective in reducing symptoms of generalised anxiety disorder [43] |
Dosage: | 200 mL | Dose: 10 mL twice daily before meals |
TABLE 3.13 NUTRITIONAL SUPPLEMENTS
SUPPLEMENT AND DOSE | RATIONALE |
---|---|
Supplement providing a daily dose of approx 2000 mg vitamin C, 500 IU vitamin E, 5000 IU vitamin A, 2000 mg mixed bioflavanoids and 10 mg elemental zinc in divided doses [17, 18] | Vitamins C, E and zinc enhance wound healing and recovery [17, 18, 22, 24]; zinc supplementation reduces the incidence, severity and number of gastric lesions [17, 18]; lower levels of vitamin C have been found in people with peptic ulcers [68]; bioflavanoids have anti-allergic properties [18, 22]; may inhibit H. pylori [18] and help prevent ulcer formation [18]; vitamins A [18, 24] and E [18] help maintain integrity of the mucosal barrier |
Omega-3 fish oil 3 × 1000 mg capsules twice daily [17, 19] |
Anti-inflammatory [17, 19, 22]; protective against peptic ulcer disease [17] |
L-glutamine 1500 mg daily in divided doses [18] |
Protects gastrointestinal mucosa from damage and promotes repair [19, 45]; indicated for use to prevent and heal peptic ulcers [22, 45] |
High-potency practitioner-strength multivitamin and mineral complex providing therapeutic doses of B-group vitamins Dosage as recommended by manufacturer |
B vitamins are beneficial to support Dan’s stress response [19, 22]; a broad-spectrum multivitamin and mineral supplement can help increase levels of essential nutrients and antioxidants which may be deficient due to Dan’s diet and lifestyle |
High-potency practitioner-strength probiotic supplement containing therapeutic levels of human strain Lactobacillus and Bifidobacterium organisms [46, 47] Dosage as recommended by manufacturer |
Probiotic supplementation can inhibit H. pylori [46, 47] and in combination with antibiotic therapy may increase its eradication rate [46, 47] and reduce antibiotic side effects [46]; probiotics can stabilise gastric barrier function [46] and decrease mucosal inflammation [46] |
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Irritable bowel syndrome
Case history
Analogy: Skin of the apple |
Analogy: Flesh of the apple | Context: Put the presenting complaint into context to understand the disease |
AREAS OF INVESTIGATION AND EXAMPLE QUESTIONS | CLIENT RESPONSES |
Family health history | |
Is there a family history of similar symptoms to what you have been experiencing? | My brother used to complain a lot of digestive concerns before he died in a motorcycle accident 10 years ago. |
Trauma and pre-existing illness | |
Have you experienced any other illness that may seem unrelated to your current symptoms? | I’ve been tested for haemochromatosis. My mother has this condition passed down from both her parents. I have one gene but have been told I won’t develop symptoms. |
Functional disease | |
Do you experience urgency to pass a watery bowel motion in the morning when you wake? (colon and functional disorder) | Sure do, right on time! |
Infection and inflammation | |
Analogy: Core of the apple with the seed of ill health | Core: Holistic assessment to understand the client |
Areas of investigation and example questions | Client responses |
Emotional health | |
Can you remember a time when you felt extremely healthy and happy? | I felt great around my 40th birthday. My wife and son were with me and we had a really special day. I remember feeling I had everything I needed to make me happy. |
Education and learning | |
Do you feel like you have learned anything significant about yourself through the process of your divorce over the past four years? | I was surprised at how much sadness and anger I had to deal with and how long it took me to let go. I learned that I’ve been working through much underlying grief from my brother’s death. I have learned that I really miss seeing my son. |
TABLE 3.17 ADRIAN’S SIGNS AND SYMPTOMS
Results of medical investigations
Conditions and causes | Why unlikely |
---|---|
OBSTRUCTION AND FOREIGN BODY | |
Kidney stones: hyperoxaluria disorders of uric acid metabolism may develop with inflammatory bowel disease and dehydration | Colic pain usually radiates from the loin to the groin about every 10 minutes; it can be very sharp pain in acute episodes; urinalysis NAD |
DEGENERATIVE AND DEFICIENCY | |
Peptic/duodenal ulcer: abdominal pain and bloating | Not common to be associated with diarrhoea; usually severe episodes of upper or midgut abdominal pain; usually will not eat due to pain after ingesting food |
INFECTION AND INFLAMMATION | |
Gastroenteritis: abdominal pain, diarrhoea | Associated with vomiting, nausea and fever; Adrian has no low-grade fever; acute gastritis is usually self-limiting and lasts less than a week; it is possible, however, to develop functional bowel disease after an acute infective episode [62] |
Bacterial infection: e.g. Yersinia enterocolitica, Escherichia coli, Shigella, Staphylococcal enterocolitis, ileocaecal TB; diarrhoea is the main symptom; may cause ulceration and inflammation; diarrhoea, abdominal pain, bloating [73, 74] | Usually self-limiting and acute in duration between 1 and 10 days depending on bacterial toxin; violent vomiting can be associated; no bloody diarrhoea reported |
Viral infection: retrovirus, hepatitis; diarrhoea, tired, nausea, fatigue, weight loss; recently travelled to new environment | No history or signs of jaundice; stools are not pale; no fever, nausea or change in appetite |
Parasitic infection: giardia, amoebiasis |
H. pylori infection: abdominal pain, bloating
Case analysis
Not ruled out by tests/investigations already done [1, 3–7, 11, 13, 57–59] | ||
CONDITIONS AND CAUSES | WHY POSSIBLE | WHY UNLIKELY |
ALLERGIES AND IRRITANTS | ||
Food allergy: typically to cow’s milk, egg, soya, peanut, wheat and fish [29, 67] | Diarrhoea, cramping colic | Often presents with swelling of lips and tongue, urticaria skin rash, conjunctivitis, rhinitis, anaphylaxis and difficulty breathing; has not linked symptoms to a particular food yet |
Lactose and fructose intolerance [29, 78] | Abdominal pain, bloating, watery and frothy diarrhoea; possible recurrent abdominal pain with onset of lactose ingestion | No nausea; need to investigate how Adrian’s diet has changed |
CANCER AND HEART DISEASE | ||
Bowel cancer, polyps, gastrointestinal lymphoma [58] | Usually associated with alternating diarrhoea and constipation; more common in middle-aged men; carcinomas and polyps can cause irritation and hypermotility | Usually presents with blood in the stool; abdominal pain is more often an advanced symptom |
Lymphoma: malignant lymphadenopathies may infiltrate the small intestine and cause diarrhoea and malabsorption; increased risk if coeliac disease present | Diarrhoea | No significant weight loss and fatigue recently; usually associated with significant fever and night sweats |
OBSTRUCTION AND FOREIGN BODY | ||
Intestinal obstruction e.g. faecal impaction with overflow | Abdominal pain, constipation, diarrhoea, abdominal distension; can be acute and recurrent abdominal pain | Can cause vomiting; Adrian’s abdominal pain is not exclusively worse after eating meals |
FUNCTIONAL DISEASE | ||
Functional abdominal pain syndrome [59] | Abdominal discomfort that can be continuous | Abdominal pain is not exclusively connected with physiological events such as eating or passing a bowel motion |
Functional diarrhoea [59] | Chronic diarrhoea and anxiety; no bleeding from the bowel, weight loss or ongoing fatigue; bowel motions are watery and mushy | Usually symptoms are in absence of abdominal pain; Adrian has bowel motions first thing in morning but need to clarify if he also has further passing during the day; defecation not exclusively after eating food for Adrian |
Functional constipation: more than 1 in 4 bowel motions are lumpy, hard and need to strain, has feeling of incomplete evacuation or blockage; has fewer than 3 evacuations a week and may need manual help to facilitate bowel motions [59] | Constipation | Adrian has constipation that alternates with diarrhoea and has more than 3 evacuations a week |
Functional abdominal bloating [59] | Bloating and visible distension | Functional bloating will not usually be relieved by passing a bowel motion |
Irritable bowel syndrome: a combination of functional pain, diarrhoea, constipation and bloating [57, 59] | Diarrhoea, recurrent episodes, symptom-free episodes, stress; abdominal pain on lower left side; usually alternates between constipation and diarrhoea; bowel motions are rarely nocturnal; poor diet | |
DEGENERATIVE AND DEFICIENCY | ||
Ulcerative colitis | Diarrhoea and lower abdominal pain | Usually affects the rectum alone; may spread to the whole colon but rarely affects the ileum; no blood and mucus in stools, which would usually be present; no significant weight loss, fever or fatigue |
Diverticular disease: diverticula and diverticulitis | Chronic symptoms include abdominal pain and diarrhoea; usually pain in the left lower abdomen; can experience erratic bowel habits; more common for those eating a low-fibre diet | Usually affects people who are over 50 years of age; usually would present with blood or mucus in stools |
Causal factor: Bile acid malabsorption: due to conditions such as Crohn’s disease, coeliac disease, increased small intestine transit, diabetic diarrhoea, postinfective gastroenteritis [62] |
Under-diagnosed cause of chronic diarrhoea; when terminal ileum fails to reabsorb bile salts causes diarrhoea and increases colonic motility | |
INFECTION AND INFLAMMATION | ||
Appendicitis | Abdominal pain, constipation; can be vague symptoms before an acute episode | More common to be right-sided abdominal pain, but can refer to the left side in some cases; usually associated with midgut belly button pain; diarrhoea not as common as a key symptom; no fever, vomiting or loss of appetite |
Crohn’s disease | Diarrhoea, recurrent episodes of watery bowel and lower abdominal pain | No key symptoms of weight loss, fever, nausea or blood and mucus in stools; Adrian only passes a bowel motion during the day |
Small-bowel disease | Chronic bacteria overgrowth due to small-bowel obstruction – diarrhoea, lower abdominal discomfort | Weight loss is not a key symptom |
Candidiasis and dysbiosis | Diarrhoea and abdominal distension | Adrian has not been on medication or antibiotics recently; no reports of feeling significant fatigue; abdominal pain is not a key symptom of candidiasis |
SUPPLEMENTS AND SIDE EFFECTS MEDICATION/DRUGS | ||
Supplement or food additive abuse: excess vitamin C or magnesium? | Diarrhoea, abdominal pain | Adrian is not taking any supplements at this time |
Drug induced (e.g. Pseudomembranous colitis) | Diarrhoea caused by recent antibiotic use (allow overgrowth of fungi), laxatives, antihypertensives, NSAIDs | Not usually associated with episodic abdominal pain; no recent antibiotic use |
ENDOCRINE/REPRODUCTIVE | ||
Pancreatic disorders: chronic pancreatitis, vipoma (endocrine pancreatic tumour), Zollinger-Ellison syndrome [79] | Symptoms of abdominal pain, episodes of diarrhoea, fatty diet; slimy bowel motion | Constipation not usually a symptom; no significant blood or mucus reported in stools; usually upper abdominal pain similar to ulcer or gall bladder colic |
Hyperthyroidism | Diarrhoea and anxiety, weight loss; common to present between 20 and 40 years of age | No goitre or eye symptoms presenting as clinical markers; Adrian not experiencing high levels of anxiety now or restlessness, energy levels are moderate |
AUTOIMMUNE DISEASE | ||
Coeliac disease [71] | Abdominal pain, poor diet, diarrhoea | More often upper abdominal pain with bloating |
STRESS AND NEUROLOGICAL DISEASE | ||
Depression [65, 69, 72] | Often presents as physical symptoms such as diarrhoea; spending more time on his own since his divorce 4 years ago | No loss of appetite, still very active at work, no significant fatigue reported |
Anxiety [69, 70, 72, 79] | Not as socially active as he used to be, diarrhoea | No reports on lack of sleep, palpitations, tight chest, difficulty breathing, loss of appetite, fast talking |
Phobia: intense fear to specific or set of stimuli that are predictable | Has mentioned not socialising as much recently | Adrian is not experiencing symptoms of anxiety that are restricted to a specific event; has not mentioned avoidance of a specific object or event |
EATING HABITS AND ENERGY | ||
Causal factor: Dehydration |
Chronic diarrhoea, not drinking much water, drinking a lot of tea and coffee; symptoms can be asymptomatic, however, colicky pain in the abdomen may be present that can be dull, constant and intermittent |
TABLE 3.20 DECISION TABLE FOR REFERRAL [1, 3–6, 12]
COMPLAINT | CONTEXT | CORE |
---|---|---|
Referral for presenting complaint | Referral for all associated physical, dietary and lifestyle concerns | Referral for contributing emotional, mental, spiritual, metaphysical, lifestyle and constitutional factors |
REFERRAL FLAGS | REFERRAL FLAGS | REFERRAL FLAGS |
TABLE 3.21 FURTHER INVESTIGATIONS THAT MAY BE NECESSARY [1–6, 11, 14]
TEST/INVESTIGATION | REASON FOR TEST/INVESTIGATION |
---|---|
FIRST-LINE INVESTIGATIONS: | |
Abdominal examination: guarding, rebound tenderness, palpation, abdnormal pulsations (auscultation) | Monitor bloating and distension for abdominal mass |
Full blood count | Low haemoglobin in Crohn’s disease, detect anaemia of chronic disease (usually normocytic, normochromic anaemia, and rarely megaloblastic due to B12 deficiency), inflammation, infection or tumour; iron deficiency anaemia; white-blood-cell count raised in appendicitis |
ESR (erythrocyte sedimentation rate)/CRP (C-reactive protein) | Inflammation, tumour, infection |
Blood electrolytes | Addison’s disease, kidney infection, dehydration |
Stool test [68] | Detect ova, parasites, bacteria, calprotectin and fat levels, and occult blood; if acidic stools are passed it indicates lactose intolerance |
Abdominal x-ray | Appendicitis, intestinal obstruction, ulcerative colitis |
Elimination diets | Detect food intolerance |
IF NECESSARY: | |
Hydrogen breath test | To detect bacterial overgrowth; when bacteria is metabolised by lactose or glucose there is a production of hydrogen; can detect fructose intolerance |
Liver function test | Hepatitis, substance abuse |
Fasting blood glucose test | Diabetes, Addison’s disease, raised in pancreatitis |
Antigliadin antibodies | Check if antibodies to gluten are present in blood |
Sigmoidoscopy | To test for Crohn’s disease |
Colonoscopy and biopsy | Rule out bowel cancer, polyps, inflammatory bowel disease, diverticulitis or haemorrhoids |
Serum B vitamins and iron | Possible malabsorption and poor diet [16] |
Hair tissue mineral analysis | To determine the presence of heavy metals [16] and ascertain tissue mineral status due to malabsorption and poor diet |
Confirmed diagnosis
Adrian and irritable bowel syndrome
The condition of irritable bowel syndrome (IBS) has a working criteria [57] of symptoms including abdominal discomfort for 12 or more weeks with at least two of the following features [59]:
• pain relieved by passing a bowel motion
• onset of abdominal discomfort associated with change in bowel motion
• more than three abnormal stools a day alternating with fewer than three stools a week
• consistent abnormal stool formation that can appear ribbon-like
• needing to strain when passing a bowel motion
A more generalised criterion for IBS is that the condition involves abdominal discomfort with changeable bowel motions in the absence of structural or biochemical disorders [57]. However, it is suggested more research is needed to ascertain whether low-grade inflammation may be present for some individuals with IBS [65].
There can be symptom-free intervals and symptoms are often associated with: increased stress, sexual and emotional abuse and trauma; family history of bowel disease and other social factors; and diet [57, 69, 72].
General references used in this diagnosis: 2, 4, 5, 11, 57–61, 63, 75
Prescribed medication
TABLE 3.22 DECISION TABLE FOR TREATMENT (ONCE DIAGNOSIS IS CONFIRMED)
Complaint | Context | Core |
---|---|---|
Treatment for the presenting complaint and symptoms | Treatment for all associated symptoms | Treatment for mental, emotional, spiritual, constitutional, lifestyle issues and metaphysical considerations |
TREATMENT PRIORITY | TREATMENT PRIORITY | TREATMENT PRIORITY |
• Lifestyle recommendations to reduce stress-induced symptoms • Dietary recommendations to avoid potential dietary triggers and increase consumption of foods with a positive effect of bowel function • Physical therapy suggestions to help reduce frequency and severity of symptoms • Herbal tea, tonic or tablets, powder and/or capsules to help reduce frequency and severity of symptoms • Nutritional supplements to help reduce frequency and severity of symptoms |
• Lifestyle recommendations to improve general health and wellbeing
• Dietary recommendations to improve nutritional status and general health
• Dietary recommendations to consume foods with anti-inflammatory properties to reduce potential gastrointestinal inflammation
• Supplemental nutrients to improve nutritional status and gastrointestinal health
• Herbal tonic and tablets with adaptogenic and tonic action to improve Adrian’s vitality and general health
• Lifestyle and physical treatment recommendations to reduce stress
• Recommendation for Adrian to attend counselling to deal with his emotional issues
• Recommendation for Adrian to become more socially active
• Herbal tea, tonic and tablets to support Adrian’s nervous system and stress response
• Herbal tonic or tablets with antidepressant action
NB: If Adrian decides to take the prescribed antidepressant medication his herbal tonic or tablets will need to be reformulated to exclude St John’s wort
Treatment aims
• Identify and eliminate foods that may be causing or aggravating Adrian’s symptoms [15–18, 29].
• Reduce or eliminate symptoms of bloating, flatulence and abdominal pain [15–18].
• Reduce exaggerated gut response to stress [15–18, 26].
• Support Adrian’s stress response [16–18].
• Support normal serotonergic signalling and response [16, 17, 24, 25].
• Reduce mucosal inflammation and modulate the inflammatory response in Adrian’s gastrointestinal tract [27, 28].
• Support healthy intestinal microflora [15–18, 46].
• Determine whether Adrian has any micronutrient deficiencies; improve his diet and nutritional status [81].
Lifestyle alterations/considerations
• Encourage Adrian to use stress-management techniques such as meditation, yoga and other relaxation techniques [16–18, 30].
• Encourage Adrian to exercise regularly [17, 32]. Exercise will help to improve Adrian’s sense of general wellbeing and reduce stress and depression [31]. Regular physical activity is likely to provide symptom improvement [17, 32].
• Encourage Adrian to cook proper meals for himself. He may find cooking classes are beneficial and may help him to enjoy cooking.
• Encourage Adrian to seek counselling to help him deal with the break-up of his marriage. Psychotherapy [35] and cognitive behavioural therapy [33, 34] are also likely to provide ongoing benefit for his physical symptoms.
• Adrian may find hypnotherapy is beneficial [37].
• Encourage Adrian to get out socially. He may try joining a club or sporting group where he can meet new people and become less isolated. He may even find a new partner.
Dietary suggestions
• Identify and eliminate any foods to which Adrian is allergic or intolerant [15–18, 29, 37]. Food intolerance is a major factor in the pathogenesis of IBS [17, 18, 29, 37]. Commonly implicated foods include barley [15, 17], chocolate [15], citrus fruit [15], coffee [15, 16], corn [15, 17], dairy food [15, 37], eggs [15, 37], garlic [15], nuts [15], oats [15, 17], onions [15], potatoes [15], rye [15, 17], soy [15], tea [15, 16] and wheat [15, 17, 37].
• Encourage Adrian to also eliminate alcohol, refined carbohydrates, sugar, fats and hot spices from his diet [15, 17, 18].
• Encourage Adrian to avoid sugar alternatives such as sorbitol, xylitol or mannitol as these may exacerbate flatulence [15].
• Encourage Adrian to eat a fibre-rich whole-food diet [15–17]. Soluble fibre is particularly beneficial to Adrian [51].
• If Adrian finds legumes and beans aggravate his symptoms, he may find them tolerable if they are soaked in water prior to cooking and the water used to soak them is discarded [15].
• Encourage Adrian to increase his intake of water [15, 16].
• Adrian will benefit from including soluble fibre in his diet [15–18, 51]. Ensure Adrian is not sensitive to cereal grains before recommending cereal fibre [16].
• Adrian could include ginger and turmeric in his diet [16].
Physical treatment suggestions
• Adrian may find acupuncture helpful in managing his symptoms. It may also improve his general wellbeing and stress response [80].
• Massage therapy [36] or aromatherapy massage [38] is likely to help Adrian as part of a stress-management program.
• Hydrotherapy: alternating hot and cold showers to the abdomen and spine [52]. Hot trunk wrap [52]. A hot sitz bath for abdominal pain [53]. A hot apple cider vinegar and water compress on the abdomen [53]. For acute diarrhoea, brief cold sitz baths with apple cider vinegar from a few seconds up to 10 minutes every day for a week, then every second day after symptoms subside [53].
• Constitutional hydrotherapy [52, 54, 55].
• For constipation place a hot compress on the abdomen, cover it in plastic, then place a hot water bottle or heating pad on top for 12 minutes. Follow this with cold mitten friction for 30 seconds. Repeat this process three times [56].
• Take a hot shallow bath or hot foot bath for abdominal bloating and pain [56].
• To tone the abdomen when not experiencing pain, apply a cold, wet compress on the abdominal area, covered by a dry towel with an elastic bandage around the trunk at night for at least three months [53].
HERB | FORMULA | RATIONALE |
---|---|---|
Damiana Turnera diffusa |
50 mL | Traditionally used in Western herbal medicine as an antidepressant and anxiolytic [19, 21, 22]; particularly beneficial where there is a sexual factor involved [19] |
Skullcap Scutellaria laterifolia |
40 mL | Nervine tonic [45]; spasmolytic [15, 45]; mild sedative [15, 45]; BHP indication for nervous tension [21] |
St John’s wort Hypericum perforatum |
60 mL | Antidepressant [19, 20, 39]; anxiolytic [20, 39]; nervine [19, 20] |
Rhodiola Rhodiola rosea |
50 mL | Adaptogen [42, 44]; tonic [42, 44]; antidepressant [42, 43]; anxiolytic [42–44] |
Supply: | 200 mL | Dose: 10 mL twice daily |
Alternative to tea and coffee | ||
HERB | FORMULA | RATIONALE |
Chamomile Matricaria recutita |
3 parts | Antispasmodic [19, 20]; sedative [19, 20]; anti-inflammatory [19, 20]; carminative [20]; traditionally used to treat gastrointestinal conditions such as colic, flatulence, cramping, diarrhoea, restlessness and anxiety [19, 20, 39, 21] |
Peppermint Mentha × piperita |
2 parts | Spasmolytic [19, 20]; carminative [19, 20]; traditionally use therapeutically for digestive disorders such as colic, flatulence, cramping [19, 20]; peppermint oil has been shown to improve symptoms of IBS [19, 39] |
Lemon balm Melissa officinalis |
1 part | Anxiolytic [19, 22] sedative [19, 22]; spasmolytic [19, 22] |
Ginger root powder Zingiber officinalis |
¼ part | Carminative [19, 20]; spasmolytic [19, 20]; traditionally used therapeutically for digestive disorders such as colic, cramping and flatulence [19, 20, 39] |
Infusion: 1 tsp per cup, 1 cup three to four times daily |
TABLE 3.25 TABLET ALTERNATIVE TO HERBAL LIQUID: MAY IMPROVE COMPLIANCE
HERB | DOSE PER TABLET | RATIONALE |
---|---|---|
St John’s wort Hypericum perforatum |
750 mg | See above |
Damiana Turnera diffusa |
675 mg | See above |
Schisandra Schisandra chinensis |
625 mg | Adaptogen [19, 23]; hepatoprotective [19]; nervine tonic [23] |
Skullcap Scutellaria laterifolia |
500 mg | See above |
Dose: 2 tablets twice daily |
TABLE 3.26 ADDITIONAL FORMULA TO HERBAL TONIC OR TABLET
HERB | DOSE | RATIONALE |
---|---|---|
Slippery elm bark powder capsules or powder Ulmus fulva |
One 500 mg capsule 4 times daily [21, 39] or ½ tsp powder mixed with hot water 3–4 times daily [19] | Nutritive demulcent [19, 21]; bulking agent and prebiotic [40]; traditionally used for diarrhoea and constipation [19, 39]; indicated for use in IBS [19, 39, 40] |
Peppermint oil Mentha × piperita |
One 200 mg enteric coated capsule 3 times daily [41] | See above Enteric-coated peppermint oil improves symptoms of IBS [16–19, 39, 41] |
TABLE 3.27 NUTRITIONAL SUPPLEMENTS
SUPPLEMENT AND DOSE | RATIONALE |
---|---|
High-potency practitioner-strength probiotic supplement containing Lactobacillus plantarum [15–17, 37, 46, 47] and Lactobacillus GG [37] Dosage as directed by the manufacturer |
Supplementation with specific strains of probiotics may improve symptoms of IBS [15–18, 37, 46, 47]; probiotic supplementation can improve intestinal health [50] |
Prebiotic supplement containing fructo-oligosaccharides (FOS) [16, 37] Dosage as directed by the manufacturer |
Taking a prebiotic together with a probiotic supplement can support growth of the probiotic organisms [48]; supplemental FOS may improve symptoms of IBS [16, 49] |
High-potency practitioner-strength multivitamin and mineral supplement providing therapeutic doses of essential micronutrients Dosage as directed by the manufacturer |
Adrian’s diet is poor and lacking in important micronutrients; diarrhoea may have depleted nutrient levels [81]; particularly important if tests show Adrian has specific micronutrient deficiencies |
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Gallstones (cholecystitis)
Case history
Analogy: Skin of the apple |
Analogy: Flesh of the apple | Context: Put the presenting complaint into context to understand the disease |
AREAS OF INVESTIGATION AND EXAMPLE QUESTIONS | CLIENT RESPONSES |
Obstruction | |
How does movement affect your abdominal pain? (obstruction of gall bladder, biliary tree or ureter from stones will be relieved by movement) | Yes. Sometimes when I have the pain I just need to keep moving, I feel really restless and cannot keep still. |
Recreational drug use | |
Have you had any significant amounts of alcohol recently? | I have not told my host family, but the daughter of the family next door and I like to go out on a weekend and drink a fair bit of beer and spirits and I stay with her overnight. It helps me feel like I’m still on holiday. |
Analogy: Core of the apple with the seed of ill health | Core: Holistic assessment to understand the client |
AREAS OF INVESTIGATION AND EXAMPLE QUESTIONS | CLIENT RESPONSES |
Home life | |
How are you getting on with the family you are living with in Australia? | They are nice people and very accepting of me. They are hard workers though and expect a lot of me. They don’t know how much pain I’m in sometimes. |
Action needed to heal | |
If your parents were here now, what would you want to say to them regarding how you left each other? | I wish they took the time to listen to me before judging me. |
TABLE 3.31 KARIN’S SIGNS AND SYMPTOMS [1, 3, 5]
TABLE 3.32 RESULTS OF MEDICAL INVESTIGATIONS [1–3, 5, 6, 11, 13]
TEST | RESULTS |
---|---|
Abdominal examination: guarding, rebound tenderness, palpation, abnormal pulsations (auscultation) | No sign of appendicitis, pancreatitis, kidney swelling, enlarged liver, bowel obstruction or perforated ulcer; positive Murphy’s sign for inflamed gall bladder |
Cholecystography: oral ingestion of radio-opaque iodinated dye with x-ray | Lack of all dye passing through bile duct into the gall bladder indicates mild acute cholecystitis |
Plain abdominal x-ray | Reveals gallstones, rules out intestinal obstruction, appendicitis |
Ultrasound examination | Reveals distension of gall bladder for acute cholecystitis, shows gall bladder wall thickening, distention of gall bladder and presence of biliary sludge |
Full blood count | Moderate leucocytosis |
ESR/CRP | Inflammation status raised |
Cholesterol blood test | Raised |
Fasting blood lipid test | High LDL, low HDL |
Liver biochemistry blood work | Serum bilirubin, alkaline phosphatase (ALP), γ-glutamyl transpeptidase (γ-GT) and aminotransferase slightly raised |
Serum amylase levels | Not elevated |
Serum albumin levels | Not elevated |
Stool test | No ova, parasites, bacteria and fat, or occult blood; stools not acidic stools, which would indicate lactose intolerance |
Electrolyte blood test | All within normal range |
Urine microscopic investigation | No urine crystals and red blood cells |
Serum assay for β-HCG | Negative |
Fasting blood-sugar test | NAD |
TABLE 3.33 UNLIKELY DIAGNOSTIC CONSIDERATIONS
Diagnostic considerations that have been ruled out [1, 3, 5–7, 11] | |
CONDITIONS AND CAUSES | WHY UNLIKELY |
FAMILY HEALTH – INHERITED | |
Choledochal cyst: due to congenital cystic disease of the bile duct | Symptoms similar to bile duct stones usually present in childhood; has not experienced current symptoms in the past |
Caroli’s syndrome: rare inherited disease of bile duct and liver; can be associated with gallstones; intermittent abdominal pain and fever with mild jaundice present; family history of symptoms | No dilated intrahepatic ducts detected on ultrasound |
CANCER AND HEART DISEASE | |
Gall bladder polyp: adenomas most common benign neoplasm of gall bladder; polyps are inflammatory and composed of cholesterol deposits | Ultrasound did not pick up polyp size masses |
Primary cancer of the gall bladder: adenocarcinoma; may only be detected at time of cholecystectomy for gallstones; more common in women; gall bladder stones and polyps, and chronic cholecystitis has been associated with gall bladder cancer; symptoms of rapid weight loss and gallstones | Usually occurs from 60 years of age and onwards; CRP did not indicate cancer |
Primary cancer of the bile duct: cholangiocarcinoma | Rare cancer; associated with significant jaundice and imaging did not show signs; CRP did not indicate cancer |
Hypertension | Blood pressure is in normal range |
OBSTRUCTION AND FOREIGN BODY | |
Acute cholangitis (inflammation of bile duct) and bile duct stones: abdominal pain, biliary colic symptoms | Fever is rare unless biliary sepsis has caused septicaemia; usually has significant jaundice; x-ray and ultrasound did not reveal stones in the common bile duct; serum amylase usually mildly elevated |
Bile pigment gallstones: black and brown stones (less common than cholesterol) | No significant haemolytic disease or duct disease |
Kidney stones: severe abdominal pain | Abdominal pain usually is lower and radiates to the lower back and groin rather than the upper abdomen and shoulder; no urine crystals and red blood cells |
Intestinal obstruction: pain in the abdomen, nausea, decreased appetite and change in bowel motion | Usually nausea, vomiting and constipation as key symptoms; abdominal x-ray and ultrasound did not detect obstruction |
Constipation: can cause slow colonic transit time that influences bile salt pool | Abdominal x-ray showed no faecal mass |
DEGENERATIVE AND DEFICIENCY | |
Perforated peptic ulcer: pain in the abdomen that is radiating, nausea, decreased appetite [41] | Usually vomiting on onset and previous history of ulcer disease; serum amylase levels not raised significantly; ultrasound did not detect any sign of ulcers; the pain of gallstone colic/cholecystitis does not have periodicity like an ulcer |
INFECTION AND INFLAMMATION | |
Non-calculous cholecystitis: chronic inflammation in the wall of the gall bladder without gallstones | Ultrasound scanning revealed the presence of gallstones; this condition is more common in the elderly and critically ill |
Appendicitis: pain in the upper right quadrant of the abdomen that is radiating, nausea, loss of appetite, increased diarrhoea and constipation, change in diet | Abdominal ultrasound did not detect an inflammation of the appendix |
Acute gallstone pancreatitis: pain in the abdomen that is radiating, nausea, decreased appetite, change in bowel motions; commonly caused by gallstones that block the pancreatic drainage; often associated with alcoholic binge | Usually associated with significant fever, nausea and vomiting; upper abdominal pain radiates to the lower back rather than the shoulder like gallstone pain; serum amylase levels usually markedly raised; no pancreatic swelling shown in the abdominal examination or ultrasound; no dilated intrahepatic ducts detected on ultrasound |
Hepatitis: pain in the upper right quadrant of the abdomen that is radiating, nausea, loss of appetite, increased diarrhoea and constipation, change in diet; serum bilirubin, alkaline phosphatase (ALP), γ-Glutamyl transpeptidase (γ-GT) and aminotransferase slightly raised | Serum albumin levels not elevated; no anaemia or viral markers in full blood count; no liver abnormalities detected on the abdominal ultrasound examination |
Crohn’s disease: can affect bile salt content in the colon to predispose to cholesterol gallstones; diarrhoea experienced with change of diet; ESR raised indicating inflammation | Usually low haemoglobin in Crohn’s disease, did not detect anaemia of chronic disease (usually normocytic, normochromic anaemia, and rarely megablastic due to B12 deficiency); no blood or mucus in stools; abdominal x-ray showed no indication of inflammation in the large intestine or colon |
ENDOCRINE/REPRODUCTIVE | |
Diabetes: can influence gall bladder motility to predispose to cholesterol gallstones | Urinalysis NAD; fasting blood-sugar NAD |
Pregnancy/ectopic or normal: Karin is of child-bearing age and may be sexually active; pain is building in intensity, pain in the abdomen with nausea and loss of appetite | Will have symptoms of missed or delayed menstrual period, vaginal discharge, lower abdominal pain; serum assay for β-HCG test is negative |
Ovarian cyst: abdominal pain | Abdominal ultrasound did not detect a cyst on the ovaries; abdominal pain is usually lower and radiates to the lower back rather than the upper abdomen and shoulder |
AUTOIMMUNE DISEASE | |
Primary sclerosing cholangitis: chronic autoimmune cholestatic liver disease with fibrosis and inflammation of the bile duct; often associated with inflammatory bowel disease; often raised serum alkaline phosphatase | More common in men over 40 years of age; no itching of skin or significant jaundice |
TABLE 3.34 CONFIRMED DIAGNOSIS [3, 5, 11, 40]
CONDITION | RATIONALE |
---|---|
Acute cholecystitis/gallstone colic (cholesterol gall stones) | Pain in the right upper quadrant that can be mild, subside quickly and then gradually build in intensity; severe upper right abdominal pain develops; feverish feeling and nausea are associated symptoms; pain radiating to the right shoulder is indicative of referred pain from the gall bladder; can be asymptomatic for years; change of diet to include more high-cholesterol foods; episode of rapid weight loss recently; feeling ‘bitter’ towards family with suppressed anger; can present with family history of gall bladder symptoms |
Test results | Positive Murphy’s sign for inflamed gall bladder; ultrasound revealed minimal gallstones that have caused pressure on the neck of the gall bladder and cystic duct |
TABLE 3.35 POSSIBLE FURTHER DIFFERENTIAL DIAGNOSIS [3–7, 11]
Not ruled out by tests/investigations already done | ||
CONDITIONS AND CAUSES | WHY POSSIBLE | WHY UNLIKELY |
ALLERGIES AND IRRITANTS | ||
Lactose intolerance | Abdominal pain, bloating, watery and frothy diarrhoea; possible recurrent abdominal pain with onset of lactose ingestion; Karin’s diet has significantly changed since she came to Australia | No nausea; need to understand more how Karin’s diet has changed |
RECREATIONAL DRUG USE | ||
Alcohol abuse: γ-GT raised in liver biochemistry | Can be raised even with a small intake of alcohol; binge drinking will exacerbate symptoms of cholecystitis | Can be raised in parallel to ALP in gall bladder disorders; if raised when serum ALP is normal that is more likely to indicate alcohol abuse |
FUNCTIONAL DISEASE | ||
Irritable bowel syndrome | Pain in the abdomen, alternating between diarrhoea and constipation; pain often presents similar to cholecystitis and may have in conjunction | Pain not necessarily relieved by passing a bowel motion |
INFLAMMATION | ||
Chronic cholecystitis: chronic inflammation of the gall bladder giving rise to vague symptoms of indigestion, distension and upper abdominal discomfort; can be similar to functional bowel disease; can be clinically connected to gallstones | Thickening of gall bladder wall detected on ultrasound | Not an isolated condition because connected with gallstones; not clear whether Karin had this before her gallstones developed; has not had current symptoms ever before |
AUTOIMMUNE DISEASE | ||
Coeliac disease | Abdominal pain, poor diet, diarrhoea; more often upper abdominal pain; diet has significantly changed since being in Australia; family history of symptoms | Significant lower abdominal bloating not reported |
STRESS AND NEUROLOGICAL | ||
Causal factor: Stress |
Being away from home, wanting more finances to go travelling, unresolved issues with parents, significant health concern while being in a foreign country; can exacerbate functional bowel disease | |
EATING HABITS AND ENERGY | ||
Causal factor: Hypercholesterolaemia: increased cholesterol |
Karin has been eating more red meat, dairy products and bread than she used to |
Case analysis
Working diagnosis
Gallstones
• eating foods high in cholesterol
• being female due to increased oestrogen decreasing solubility and excretion of cholesterol
• rapid weight loss or fasting due to an increase in leptin, which can increase cholesterol secretion
• bile salt loss occurring in conditions such as Crohn’s disease
• chronic constipation causing a slow colonic transit time and influencing the composition of the bile salt pool in the colon
• gall bladder motility disorders that may occur during pregnancy and diabetes
Acute cholecystitis
About 90 per cent of acute cholecystitis cases result from an obstruction of the neck of the gall bladder by gallstones. This leads to lack of gall bladder emptying, distension and inflammation. Sometimes the inflammation is mild and quickly subsides and the person may only feel a small amount of pain. It is more common for inflammation to become more severe giving rise to an acute rapid onset of pain that is localised to the middle of the abdomen or specifically in the right upper quadrant. It is at this stage that many people realise for the first time they have gallstones. The pain is continuous and increases gradually in intensity and can radiate to the back and the right shoulder. An episode of pain will slowly ease and there will usually be pain-free periods for between 30 and 360 minutes. The person may also feel nauseous, feverish and often will vomit. At this stage mild jaundice may occur.General references used in this diagnosis: 1, 3, 5, 6, 11, 40
COMPLAINT | CONTEXT | CORE |
---|---|---|
Treatment for the presenting complaint and symptoms | Treatment for all associated symptoms | Treatment for mental, emotional, spiritual, constitutional, lifestyle issues and metaphysical considerations |
TREATMENT PRIORITY | TREATMENT PRIORITY | TREATMENT PRIORITY |
• Lifestyle recommendations to reduce the incidence of acute episodes • Dietary recommendations to reduce recurrence of attacks • Physical therapy recommendations for symptomatic relief • Herbal tonic to support bile flow and formation and to help reduce further stone formation NB: Herbal choleretics and cholagogues are contraindicated in septic cholecystitis where there is a risk of peritonitis; collaborative management of Karin’s case with her GP is therefore essential to ensure there are no contraindications to herbal therapy |
• Lifestyle recommendations to help reduce stone formation
• Specific dietary recommendations to help reduce and/or prevent formation and enlargement of stones
• Dietary recommendations to improve general nutrition and reduce dietary risk factors for stone development
• Herbal tonic and tea to support digestive and liver function
• Specific nutritional supplements to help reduce and/or prevent formation and enlargement of stones
TABLE 3.37 DECISION TABLE FOR REFERRAL [3, 5, 11, 12]
COMPLAINT | CONTEXT | CORE |
---|---|---|
Referral for presenting complaint | Referral for all associated physical, dietary and lifestyle concerns | Referral for contributing emotional, mental, spiritual, metaphysical, lifestyle and constitutional factors |
REFERRAL FLAGS | REFERRAL FLAGS | REFERRAL FLAGS |
ISSUES OF SIGNIFICANCE | ISSUES OF SIGNIFICANCE | ISSUES OF SIGNIFICANCE |
REFERRAL DECISION | REFERRAL DECISION | REFERRAL DECISION |
TABLE 3.38 FURTHER INVESTIGATIONS THAT MAY BE NECESSARY [1, 3–6, 11, 13]
Test/investigation | Reason for test/investigation |
---|---|
FIRST-LINE INVESTIGATIONS: | |
Hydrogen breath test | To detect bacterial overgrowth; when bacteria is metabolised by lactose or glucose there is a production of hydrogen |
Elimination diet | Detect food intolerance |
IF NECESSARY: | |
Oral tolerance lactose test | Determine lactose metabolism |
Antigliadin antibodies | Check if antibodies to gluten are present in blood indicating coeliac disease |
p-ANCA (anti-neutrophil cytoplasmic antibody) | Detect primary sclerosing cholangitis |
Serum immunoglobulins IgG and IgM | Cirrhosis of the liver, postviral disease and autoimmune disease of the liver |
Serum autoantibodies AMA | Primary biliary cirrhosis of the liver |
Magnetic resonance cholangiography (MRC) | Delineates fluid volume in bile tree, detect primary sclerosing cholangitis |
Sprial CT scanning | Detect bile duct dilatation; can exclude carcinoma as the cause of the bile duct obstruction; define if opaque or cholesterol stones; acute pancreatitis |
Endoscopic ultrasound scanning of the bile duct and gall bladder | Identify stones at the distal end of the common bile duct; invasive procedure |
Endoscopic retrograde cholangiography (ERC) | Detects primary sclerosing cholangitis |
Endoscopy | Peptic ulcer |
Sigmoidoscopy | Confirm Crohn’s disease and eliminate from differential diagnosis list |
Liver histology | Confirms primary sclerosing cholangitis |
Confirmed diagnosis
Gallstones (cholecystitis) with hypercholesterol and stress
• Analgesics as required for the pain
TABLE 3.39 DECISION TABLE FOR TREATMENT (ONCE DIAGNOSIS IS CONFIRMED)
COMPLAINT | CONTEXT | CORE |
---|---|---|
Treatment for the presenting complaint and symptoms | Treatment for all associated symptoms | Treatment for mental, emotional, spiritual, constitutional, lifestyle issues and metaphysical considerations |
TREATMENT PRIORITY | TREATMENT PRIORITY | TREATMENT PRIORITY |
Treatment aims
• Prevent bile stasis and supersaturation [14–16].
• Stimulate production and flow of bile [21].
• Increase solubility of bile [15] and solubility of cholesterol in bile [15, 19].
• Prevent further stone formation and enlargement [15].
• Reduce dietary risk factors [15–17] and improve Karin’s diet [15, 16].
Lifestyle alterations/considerations
• Encourage Karin to not be encouraged to use gall bladder flushing techniques because stones may lodge and block her bile duct [16, 17].
• Encourage Karin to ensure she protects her skin from excessive exposure to sunlight and avoids sunburn [15].
• Karin would benefit from dealing with her emotional stress [15]. Chronic stress can increase bile retention and inhibit gall bladder emptying [15]. Stress-management techniques would therefore be helpful to her.
• Karin may find counselling helpful to help her deal with the unresolved conflict with her parents [27].
• Karin would benefit from increasing her physical activity. Symptomatic cholelithiasis can be prevented by physical activity [26]. Regular exercise is associated with lower levels of stress and anxiety [29, 30].
Dietary suggestions
• Encourage Karin to drink six to eight glasses of water every day to ensure the water content of the bile is maintained [15].
• Encourage Karin to try to include turmeric in her diet as often as possible [15]. Turmeric is a choleretic [21] and is used traditionally to improve poor digestion [21]. It has also been demonstrated to reduce gallstone size [24].
• Encourage Karin to reduce her consumption of animal protein, refined carbohydrates, sugar, saturated fats and dietary cholesterol [15, 16].
• Encourage Karin to avoid all fried foods [15].
• Encourage Karin to increase consumption of fruit, vegetables and legumes [15, 16].
• Encourage Karin to increase her consumption of foods containing omega-3 fatty acids, particularly from cold-water fish [15].
• Encourage Karin to increase her consumption of soluble fibre [15, 16].
• Determine whether Karin has any food allergies and manage accordingly [15].
• Karin could include buckwheat regularly in her diet [15]. Buckwheat enhances bile acid synthesis, reduces concentration of cholesterol in the gall bladder and decreases gallstone formation [15].
• Karin could consume 1–2 tsp of lecithin granules daily [15, 16]. The phosphatidyl choline in lecithin increases phospholipids in bile, which can improve bile solubility, therefore reducing the risk of stone formation [16].
• Karin may benefit from drinking lemon juice. Lemon juice increases hepatobiliary excretion and therefore may improve digestive function [25].
Physical treatment suggestions
• Acupuncture may relieve Karin’s abdominal pain and nausea [22, 23]. It may also help reduce her anxiety and stress [29, 30].
• Karin may find massage helpful to reduce stress and anxiety [31, 32].
• Hydrotherapy: hot trunk wrap [33]. Constitutional hydrotherapy [33–35].
• Hot fomentations (5–10 minutes) with vinegar water alternating with cold (1–5 minutes) mitten frictions to abdomen and lower back [34, 35].
HERB | FORMULA | RATIONALE |
---|---|---|
Fringe tree Chionanthus virginicus |
40 mL | Choleretic [18, 21]; cholagogue [18, 19, 21]; traditionally used for cholecystitis |
Dandelion root Taraxacum officinale |
40 mL | Choleretic [18, 20]; cholagogue [19]; traditionally used to treat cholecystitis and gall stones [18, 19] |
Boldo Peumus boldo |
20 mL | Cholagogue [18, 19]; liver stimulant [18, 19]; traditionally used to treat gall bladder pain and gallstones [18, 19]; indicated for use in cholelithiasis with pain [19] |
Globe artichoke Cynara scolymus |
40 mL | Choleretic [21, 20]; cholagogue [21, 20]; antiemetic [21]; hepatoprotective [21, 20] |
St Mary’s thistle Silybum marianum |
60 mL | Choleretic [21]; hepatoprotective [21, 20] |
Supply: | 200 mL | Dose: 5 mL 3 times daily |
Alternative to tea and coffee | ||
HERB | FORMULA | RATIONALE |
Peppermint leaf
Mentha × piperita |
3 parts | Choleretic [20, 21]; antispasmodic [20, 21]; relieves nausea [20, 21] |
Chamomile flower Matricaria recutita |
3 parts | Choleretic [20]; antispasmodic [20, 21]; anti-inflammatory [20, 21]; mild sedative [20, 21] |
Ginger root (powdered) Zingiber officinale |
¼ part | Anti-emetic [20, 21]; anti-nausea [20, 21]; choleretic [20]; anxiolytic [20]; traditionally used to enhance digestion [21] |
Infusion: 1 tsp per cup – 1 cup 3–4 times daily |
TABLE 3.42 NUTRITIONAL SUPPLEMENTS
SUPPLEMENT AND DOSE | RATIONALE |
---|---|
Omega-3 fish oil 3 × 1000 mg capsules twice daily [16, 38] |
Omega-3 oils are essential for the normal formation of bile [15, 16, 38]; supplementation decreases biliary cholesterol saturation in gallstone disease [38] and improves gall bladder dysmotility [39] |
Vitamin C 1000 mg twice daily [15, 16, 37] |
High-dose vitamin C supplementation may reduce cholesterol stone formation by altering bile acid composition and increasing the time taken for gallstones to develop [16, 37] |
Soluble fibre supplement 10 g twice daily [15] |
Soluble fibre reduces biliary cholesterol saturation and cholesterol stone formation [16, 36] |
Lipotropic supplement providing approx. 1000 mg choline [15, 16], 800 mg l-methionine [15, 16] and 3 g taurine [5, 15, 16] daily | Lipotropic factors are essential for normal liver metabolism of fat and bile flow [15, 16]; taurine increases bile acid pool and prevents gallstone formation [5, 28] |
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