Dry Age-Related Macular Degeneration
Clinical Features:
The hallmark feature of dry AMD is the presence of drusen, which are yellow-colored subretinal deposits that range in size and appearance (Fig. 7.1.1). Small, fine drusen without other manifestations such as RPE changes or atrophy should not be considered AMD. Additionally, there can be varied pigmentary changes within the RPE. Advanced forms of AMD feature atrophy of the RPE with eventual GA, which can occur in the presence or absence of drusen (Fig. 7.1.2 and Fig. 7.1.3).
Figure 7.1.1 Color fundus photograph of dry AMD with many drusen of varying size intermixed with RPE hyperpigmentation and hypopigmentation. There is an area of geographic atrophy (arrowheads), which is difficult to appreciate clinically.