14 Drug interactions – 1
T | F | |
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1. Antacids decrease plasma levels of chlorpromazine. | ![]() |
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2. Caffeine antagonizes the anxiolytic effects of benzodiazepines. | ![]() |
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3. Carbamazepine reduces serum antipsychotic levels. | ![]() |
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4. Cimetidine decreases plasma antidepressant levels. | ![]() |
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5. Alcohol and diazepam interact pharmacokinetically. | ![]() |
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6. Acamprosate interacts with disulfiram. | ![]() |
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7. ACE inhibitors reduce lithium levels. | ![]() |
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8. Aminophylline reduces lithium excretion. | ![]() |
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9. Consuming alcohol whilst taking metronidazole can cause throbbing headache. | ![]() |
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10. Inhalational anaesthetics interact with monoamine oxidase inhibitors (MAOIs). | ![]() |
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11. Smoking increases serum antidepressant levels. | ![]() |
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12. Tricyclic antidepressants (TCAs) interact with antihypertensive drugs. | ![]() |
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13. Alcohol can both decrease and increase the levels of TCAs. | ![]() |
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14. TCAs block the depressant effects of alcohol. | ![]() |
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15. Adrenaline interacts significantly with TCAs. | ![]() |
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16. Barbiturates increase the metabolism of TCAs. | ![]() |
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17. Clozapine and carbamazepine should not be co-prescribed. | ![]() |
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18. Fluoxetine decreases clozapine levels. | ![]() |
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19. Grapefruit juice inhibits cytochrome P450 3A. | ![]() |
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20. Chlorothiazide is less likely to cause lithium toxicity than frusemide. | ![]() |
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21. Reboxetine inhibits cytochrome P450. | ![]() |
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22. SSRIs increase plasma concentrations of carbamazepine. | ![]() |
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23. TCAs enhance the effects of chlorpromazine. | ![]() |
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24. Clonidine may interact significantly with TCAs. | ![]() |
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25. Fluoxetine increases levels of diazepam. | ![]() |
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