Day-Case Anaesthesia

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Day-Case Anaesthesia

A day-case patient is one who is admitted for investigation or operation on a planned non-resident basis. Patients are usually discharged from the hospital or unit later on the day of the procedure. The procedure may require general, regional or local anaesthesia, sedative techniques or a combination of these.

The NHS plan predicts that 75% of all elective operations will be carried out as day cases. According to the British Association of Day Surgery (BADS), patients support day surgery because it provides timely treatment, less risk of cancellation, a lower incidence of hospital-acquired infection and an earlier return to normal activities. Procedures commonly selected for day-case care are those which take < 60 min to complete and which do not cause severe haemorrhage or produce excessive amounts of postoperative pain (Table 26.1). Increasingly complex cases are now performed as day-case procedures, including laparoscopic cholecystectomy and tonsillectomy. By extending day surgery opening hours and using staggered admission times, patients who would normally require hospital admission may be treated as day cases. The British Association of Day Surgery (BADS) publishes guidelines and protocols for the management of specific issues: for example, day surgery for patients with diabetes. BADS has also published a list of 25 procedures which should normally be undertaken as day cases. The NHS Modernisation Agency audited current day surgery rates for these procedures and set target rates for individual hospitals.

TABLE 26.1

A Selection of Surgical Procedures Commonly Undertaken as Day Cases

Gynaecology

Dilatation & curettage, laparoscopy, vaginal termination of pregnancy, colposcopy, hysteroscopy

Plastic Surgery

Dupuytren’s contracture release, removal of small skin lesions, nerve decompression

Ophthalmology

Strabismus correction, cataract surgery, lacrimal duct probing, examination under anaesthesia

ENT

Adenoidectomy, tonsillectomy, myringotomy, insertion of grommets, removal of foreign body, polyp removal, submucous resection

Urology

Cystoscopy, circumcision, vasectomy, transurethral bladder resection

Orthopaedics

Arthroscopies, carpal tunnel release, ganglion removal, bunion operation, removal of metalwork

General Surgery

Breast lumps, herniae, varicose veins, endoscopy, laparoscopic cholecystectomy, haemorrhoidectomy, anal fissure dilatation

Paediatrics

Circumcision, orchidopexy, squint, dental extractions

Achievement of a pain-free ambulant patient requires skilful patient selection and experienced anaesthetists and surgeons working within a day surgery unit. Large-scale reports have indicated that day surgery represents a safe, cost-effective and efficient practice. Advantages include decreased risks of nosocomial infection and deep venous thrombosis, less social disruption to patients and their families and minimal need for inpatient hospital resources. Therefore we now face the challenge of providing faster recovery, more rapid discharge and better pain relief for these patients.

PATIENT SELECTION

The selection of patients for day-case surgery is of vital importance if maximum use is to be made of the resources in the day-case unit and also to facilitate smooth running of the unit. The selection of patients must take into account two separate aspects: firstly, the patient’s state of health, and secondly, his or her social circumstances. Patients should normally be ASA I or II, or medically stable ASA III. Recent reviews have shown that patients with a body mass index of > 35 kg m−2 do not have an increase in unplanned admission rates or postoperative complications. The Association of Anaesthetists of Great Britain and Ireland has recommended that obese patients should not be excluded from day surgery based on their BMI measurement alone. There is no evidence of significant morbidity in the immediate postoperative period when treating morbidly obese patients as day-cases. Although an increased risk of adverse events occurring intraoperatively and in the immediate recovery period in obese patients has been reported, these have not been shown to increase the incidence of unplanned admission significantly.

Evidence has shown that many elderly patients cope better at home. Careful preoperative assessment should highlight patients who will require an extended time in hospital. Elderly patients are more likely to have comorbidities and these patients should be assessed according to their physiological rather than their chronological age. Careful medical and social preoperative assessment is required to help elderly patients to benefit from shorter hospital stays with less risk of postoperative confusion. The patient should stay a minimum of a 1-h drive from the hospital on the night following surgery and they should have an adult escort available for the first 24 h. An example of guidelines used for patient selection for day-case anaesthesia is shown in Table 26.2.

TABLE 26.2

Guidelines for Patient Selection for Day-Case Surgery Under General Anaesthesia

ASA 1 or 2 and medically stable ASA 3

Age: > 52 weeks post-conceptual age

Weight: body mass index = weight/height2 (kg m−2)

 ≤ 35: acceptable

 > 35: discuss with anaesthetic department

Generally healthy, i.e. can climb two flights of stairs

Exclusions

Cardiovascular

 MI/TIA/CVA within 6 months

 Hypertension: persistent diastolic pressure > 110 mmHg

 Unstable angina

 Arrhythmias

 Heart failure

 Poor exercise tolerance

 Symptomatic valve disease

Respiratory

 Acute respiratory tract infection

 Asthma requiring regular β2-agonists or steroids

Metabolic

 Alcoholism /narcotic addiction

 Insulin-dependent diabetes

 Renal failure

 Liver disease

Neurological/musculoskeletal

 Severe arthritis of jaw or neck

 Cervical spondylosis/ankylosing spondylitis

 Myopathies/muscular dystrophies/ myasthenia gravis

 Advanced multiple sclerosis

 Epilepsy > 3 fits per year

Drugs

 Steroids

 Monoamine oxidase inhibitors

 Anticoagulants

 Antiarrhythmics

 Insulin

The selection of patients for day-case surgery is made at the time of outpatient consultation and routine measurement of pulse rate and blood pressure, urine analysis and other relevant investigations (e.g. ECG, full blood count and sickle cell testing) are performed; performance of these routine tests minimizes the number of problems when patients are admitted on the day of surgery. A standardized patient health/anaesthesia questionnaire and preliminary nurse assessment with appropriate referral for anaesthetic consultation minimize difficulties encountered on the day of surgery. Pre-assessment clinics provide an opportunity to educate patients and have been shown to reduce both cancellations by patients and unnecessary preoperative investigations. Children should be treated as day cases if possible and children scheduled for day-case procedures should be healthy and usually ASA I or II. Premature babies who have not reached 52 weeks post-conceptual age should not be considered for day-case surgery because of the risk of postoperative apnoea, and special consideration should be given to babies who have been receiving ventilatory support. The parent must be able to cope with the pre-procedure instructions and with the care of the child following treatment. The parent must agree to day treatment and be available to stay throughout the day although there may be exceptions for older children who attend regularly. Home facilities and travelling conditions should be taken into account. Following a general anaesthetic, the use of public transport is inappropriate.

Following selection of a patient for day-case surgery, the nature of the operation and the routine of management are explained fully to the patient and the consent form may be signed. Many units issue the patient with explanatory leaflets, CDs/DVDs or even podcasts explaining the procedure. A date for surgery can then be arranged and registration completed, as for an in-patient admission. It is wise to book any pathological or radiological investigations which are required well in advance of the day of admission.

The patient should be given written instructions detailing the date and time of attendance at the day unit, with written instructions relating to preoperative starvation and the patient’s regular medication, e.g. antihypertensives, should be taken as usual but oral hypoglycaemics must be omitted on the morning of surgery. These instructions should be written clearly in plain English (or another appropriate language). The patient is usually advised not to eat anything from midnight for a morning operating list.

Recent clinical studies suggest that overnight fasting may not be required in adults or children. Pulmonary aspiration occurs usually in emergency abdominal and obstetric procedures where there may be complicating factors such as recent food and fluid intake, trauma or administration of opioid analgesics. These factors do not normally apply to healthy elective day-case patients. The universal order of nil by mouth from midnight should apply only to solids. Clear fluids should be allowed until 3 h before the scheduled time of surgery. The effect of giving patients 150 mL of clear fluid 2 h before general anaesthesia for termination of pregnancy has been studied; the results showed that clear fluids do not increase the incidence of regurgitation or vomiting during anaesthesia and the postoperative period and that preoperative thirst was decreased in the clear fluid group. It is advisable to ask patients who smoke to refrain from smoking for 4–6 weeks before the operation. Patients should be asked to bring with them all tablets and medicines which they take regularly.

ORGANIZATION OF THE DAY-CASE UNIT

Types Of Unit

In order to help improve the number of day-case operations, BADS has produced a directory of 160 procedures. Attached to each of these procedures are four possible management options.

There are three common types of day-case unit.

Ideally, day surgical units should not be freestanding but situated on in-patient hospital sites. The ward area should be close to the operating theatre to reduce portering time, particularly when short operations are performed. This arrangement also enables parents to accompany their children to the anaesthetic room if this is desirable.

Preferably, the unit should be near a car park and well signposted to facilitate the prompt arrival of patients and to avoid unnecessary delays.

Facilities Available

The accommodation should ideally include the following.

image An admission area, which includes reception, treatment and examination rooms, a nurses’ station, lavatories, a playroom and a discharge area.

image An anaesthetic room, fully equipped and large enough to allow free access around the patient’s trolley to permit the use of local or general anaesthesia. There should be good lighting, scavenging, piped gases and suction equipment, anaesthetic machine and monitoring equipment. The hazards and risks of general anaesthesia for day surgery are no less than those associated with elective in-patient surgery; indeed, in some respects they may be greater and the facilities provided must be at least comparable.

image An operating theatre, which should be of the same specification as the in-patient equivalent. A good operating light, air conditioning and piped services are required, in addition to the usual scrub-up and autoclave facilities. There is always the possibility of a minor operation developing unexpectedly into a major operation and this demands that the theatre is equipped to deal with that eventuality.

image A fully equipped recovery room, which must always be equipped and staffed for the safe recovery of patients following general anaesthesia. Piped gas supplies and resuscitation equipment are mandatory and the full range of monitoring and ventilation equipment must be readily available.

Other facilities which should be available include office space, an equipment store, staff changing and locker rooms, a staff room, a pantry to make drinks and lavatories for patients, parents and staff.

Admission

Patients should be admitted to the day ward in adequate time for history-taking and examination. The results of any investigation requested as an outpatient should be available and noted. Patients should receive an identity bracelet and their name should be entered into the nursing record. The surgeon should ensure that the indication for surgery is still present, e.g. presence or absence of lumps to be removed, because it may be several weeks since the clinic appointment. The consent form should be signed if not already done during the outpatient appointment, and the operation site clearly marked.

Venous thromboembolism prophylaxis should be provided according to local hospital policy based on the risk factors which are present. It is also important that careful attention is paid to WHO checklists and procedures, to maximize patient safety in the day-case environment.

A pregnancy test in women of fertile age may need to be performed if there is any risk of pregnancy. Staggering patient admissions decreases waiting times and improves the efficiency of the unit. Using dedicated paediatric day-case lists ensures an appropriate staffing mix for these patients. The use of separate operating lists for local anaesthesia and general anaesthesia may improve throughput, as does the introduction of day-surgery operating trolleys.

ANAESTHESIA

Premedication

Most anaesthetists do not routinely prescribe premedication for day-case surgery because it is usually unnecessary and for fear of delaying recovery and discharge. Premedicant drugs that may be used if required include the following.

Antiemetics

If patients are at high risk of postoperative nausea and vomiting (PONV), antiemetics may be administered orally before operation, or via the intravenous or rectal routes perioperatively. Apfel et al (2002) developed a simplified PONV risk score and suggested the use of prophylactic antiemetics for any patient with two or more of the following: female gender; past history of motion sickness or PONV; non-smoker; and use of postoperative opioids. However, risk scores such as this have no more than a 70% chance of predicting PONV.

General and Regional Anaesthesia

General, local or regional anaesthesia may be administered safely to day-case patients. The choice of technique should be determined by surgical requirements, anaesthetic considerations and the patient’s physical status and preference.

General Anaesthesia

The choice of induction and maintenance agent depends upon the requirements of the patient and the preferences of the anaesthetist. The anaesthetic induction agent used in day-case anaesthesia should ensure a smooth induction and good immediate recovery with minimal postoperative sequelae and a rapid return to street fitness.

Propofol is the induction agent used routinely in day-case anaesthesia. One of its main advantages is the ease and rapidity with which patients recover. Patients are clear-headed and have a low incidence of PONV. The inhalational agent sevoflurane may be used for induction of anaesthesia. It is non-irritant to the airways and has the advantages of rapid induction in both children and adults, minimal cardiovascular side-effects and a rapid recovery profile. However, sevoflurane causes more PONV than propofol.

Both sevoflurane and desflurane have been marketed as ideal agents for maintenance of anaesthesia for day-case surgery, with favourable recovery profiles and more rapid awakening than those associated with isoflurane. However, both sevoflurane and desflurane have been associated with emergence delirium because of rapid awakening, especially in children. In addition, desflurane is less suitable for spontaneously breathing subjects because it is more irritant to the airways than either sevoflurane or isoflurane. The use of nitrous oxide for maintenance of anaesthesia has been shown to increase the risk of PONV; however, its use does reduce the requirements for volatile agents and may reduce the risk of intraoperative awareness. Target-controlled infusion (TCI) of propofol with or without an infusion of the ultra-rapid-acting opioid remifentanil minimizes the risk of PONV and results in short recovery times; however, the analgesic effect of remifentanil is very short and other analgesic drugs must be administered to deal with analgesia for anticipated postoperative pain.

A clear airway is a fundamental requirement of safe anaesthesia. The laryngeal mask airway (LMA) is used widely, avoids the need for tracheal intubation and extubation, and thus improves turnaround time between cases. Many anaesthetists use the LMA for procedures which were thought formerly to need tracheal intubation, such as tonsillectomy or laparoscopy. The ProSeal LMA provides a higher pressure seal than a conventional LMA and has an internal lumen which aids the escape of gastric contents if necessary. There is now a wide choice of alternative supraglottic airway devices available. However, a rapid-sequence induction technique with tracheal intubation is still required for patients identified as being at risk of regurgitation and aspiration of gastric fluid; this is not a contraindication to day surgery.

The choice of muscle relaxant depends on the anticipated duration of surgery. Succinylcholine is associated with muscle pains, especially in ambulant patients, and for all but the shortest procedures is not ideal in the day-case setting (except when rapid-sequence induction is required). Of the non-depolarizing muscle relaxants (NDMRs) currently available, atracurium and vecuronium have relatively short durations of action when used in appropriate doses and are readily antagonized after 15–30 min. Mivacurium has an even shorter duration of action because it undergoes rapid hydrolysis by plasma cholinesterase, but a small number of patients may suffer prolonged muscle paralysis following the use of mivacurium because of a plasma cholinesterase deficiency. Rocuronium may have a role to play because it has a more rapid onset of action than any of the other NDMRs, providing good intubating conditions within 60–90 s following a dose of 0.6 mg kg−1 and a duration of action of 30–45 min. Cisatracurium, the stereoisomer of atracurium, has a slightly longer duration of action compared with that of atracurium but without the side-effect of histamine release.

The relatively new reversal agent sugammadex is now available for the reversal of the effects of rocuronium and vecuronium. Sugammadex is able to reverse profound rocuronium-induced muscle relaxation. This has advantages over the more conventional reversal agent neostigmine if reversal is required soon after the administration of vecuronium. There may be specific advantages associated with the use of this agent in obese patients, or those with a difficult airway, in whom rapid return of neuromuscular function is desirable.

Regional Anaesthesia

Spinal anaesthesia has been used for day-case anaesthesia, but the side-effects of post-dural puncture headache (PDPH) and motor weakness may delay discharge. Smaller-gauge pencil-point spinal needles have reduced the incidence of PDPH to < 1% in patients aged > 40 years. Shorter-acting local anaesthetics may increase the use of day-case spinals in the future; however, intrathecal lidocaine has been associated with transient neurological symptoms and is not licensed for intrathecal use in the UK. Prilocaine, mepivacaine and pethidine have also been used for outpatient spinals in other countries, including the United States, and hyperbaric prilocaine is now available in the UK. The new preservative-free preparation of 2-chloroprocaine may provide acceptable anaesthesia and discharge times with low potential for transient neurological symptoms, but more clinical trials are needed. Low-dose bupivacaine (3 mL of 0.17%) has been used successfully for knee arthroscopy with times to discharge of 190 min. The addition of fentanyl 10 μg increases the duration of sensory blockade without affecting discharge times.

Local anaesthetic blocks are an excellent choice for day-case patients because of the low incidence of PONV and the provision of good postoperative analgesia. Many anaesthetists now use ultrasound-guided nerve blockade routinely to improve success rates, reduce the volume of local anaesthetic required and hopefully reduce the incidence of complications. Inguinal hernia repair is performed commonly under an ilioinguinal nerve block and local infiltration. For operations on the hand or arm, axillary or mid-humeral approach to brachial plexus block is preferable to the supraclavicular approach to minimize the risk of producing a pneumothorax, which may become apparent only after discharge. Intravenous regional anaesthesia (Bier’s block) is another alternative for hand operations provided that effective exsanguination of the arm is achieved before performing the block.

Caudal block is used to reduce pain in paediatric patients after circumcision, herniorrhaphy, hypospadias or orchidopexy, using 0.25% plain bupivacaine; this provides excellent postoperative analgesia. Whenever a caudal block is administered for analgesia, care must be taken to ensure that motor strength is not compromised. There does not appear to be any advantage in using more concentrated solutions than 0.25% bupivacaine. Penile block and the application of local anaesthetic cream are also effective for circumcision.

Intra-articular local anaesthetics are useful following arthroscopy of the knee or shoulder. Femoral nerve block has been found to give superior analgesia to patients going home after anterior cruciate ligament repair and, combined with sciatic nerve block, reduces admission rates for complex knee surgery. Regional catheter techniques such as continuous interscalene brachial plexus block using a portable infusion pump allow a local anaesthetic infusion to continue at home. Analgesia is improved and side-effects from opioids are minimized. Guidance from community outreach teams improves efficacy and patient satisfaction. New elastomeric pumps which slowly infuse local anaesthetic solution at a fixed rate and which incorporate an air filter have been used safely on an outpatient basis. These pumps do not need a power source and deliver local anaesthetic directly to the surgical site.

POSTOPERATIVE CARE

Recovery from anaesthesia is an important aspect of day-case anaesthesia. The recovery area should be provided with the same range of monitoring equipment and resuscitation facilities as available in an in-patient facility. Many day surgery units in the UK now have three separate recovery areas: the first stage is for the immediate postoperative period, when patients require one-to-one nurse-to-patient care and monitoring; the second involves lower nursing dependency care where the patient is not attached to monitoring, but is mobilizing and usually given food and drink; and the third stage is the discharge area. The overall responsibility for assessing when patients are ready to go home is that of the clinicians involved. Often, experienced nursing staff who work regularly in the day unit become very good at detecting potential problems with day-case patients.

Postoperative pain control should be started pre- or intraoperatively by supplementing intravenous or inhalational anaesthesia with a combination of a non-steroidal anti-inflammatory drug (NSAID), paracetamol (especially in children), a short-acting opioid analgesic and local/regional block intraoperatively. Awakening is smoother and discharge home is quicker. The most frequently used drugs to provide intraoperative analgesia are fentanyl and alfentanil; the relatively short duration of action of these drugs makes them suitable for use in day-case anaesthesia. The provision of good postoperative analgesia is primarily the responsibility of the anaesthetist. Anaesthetists may do little to limit the number of patients requiring admission for surgical complications, but do play a major role in reducing admissions caused by pain or vomiting. NSAIDs, e.g. diclofenac, are useful for provision of postoperative analgesia in day-case patients. COX II inhibitors are available as intravenous or oral preparations and have better gastrointestinal side-effect profiles than NSAIDs and fewer antiplatelet effects. An intravenous preparation of paracetamol is available and provides good analgesia without side-effects. Multimodal analgesia reduces the requirement for postoperative opioids.

Factors contributing to postoperative nausea and vomiting include a previous history of PONV, gender (females are more susceptible), the use of longer-acting opioid analgesic drugs such as morphine, the choice of anaesthetic technique or agents, operative procedure, pain, sudden movement or position change, history of motion sickness, hypotension, obesity, day of menstrual cycle and high oestrogen levels. A relationship between pain and the frequency of nausea and vomiting in the postoperative period has been established. There is controversy regarding the use of opioid analgesics in the day-case patient because they may increase PONV. Several studies have shown that, if an opioid-nitrous oxide anaesthetic is given, the occurrence of PONV is greater compared with an inhalational anaesthetic. In contrast, there are studies that have demonstrated that an opioid-supplemented anaesthetic technique results in earlier ambulation and discharge. PONV may be treated with intravenous 5-HT3 antagonists, dexamethasone or cyclizine, and intramuscular prochlorperazine. Adequate hydration and analgesia are also of paramount importance.

In general, discharge of the patient should not take place until the patient is able to sit unaided, walk in a straight line and stand still without swaying. Usually, patients have been able to drink and eat (this also demonstrates the absence of nausea). A responsible person should be present to escort the patient home and both the responsible person and the patient should be given verbal and written discharge instructions and an adequate supply of oral analgesic drugs for at least 3 days. The patient should be advised to refrain from activities such as driving a car, operating machinery and drinking alcohol for 24 h. Communication with the patient’s general practitioner is very important to ensure awareness of the operation performed and the requirements for postoperative follow-up. A follow-up telephone call to the patient after discharge should highlight any specific problems. Table 26.3 displays typical discharge criteria for day-case patients.

TABLE 26.3

Discharge Criteria for Day-Case Patients

Stable vital signs for at least 1 h

Orientated in time, place and person

Adequate pain control

Minimal nausea, vomiting or dizziness

Adequate oral hydration

Minimal bleeding or wound drainage

Able to pass urine

Responsible escort

Discharge authorized by appropriate staff member

Written and verbal instructions given to patient

Suitable analgesia provided

Patient hotels are a relatively new concept. The patient spends the first postoperative night in a hotel near to the day surgery unit where there is a resident nurse. These have been used so far for patients who have had, for example, a tonsillectomy. Patient hotels are cheaper than an in-patient overnight stay and are useful for patients who live too far from the day unit to be considered under normal circumstances for day surgery.

Each day-care unit should have an established system for audit of outcomes related to anaesthesia and include these outcomes in quality assurance and peer review processes. Reasons for non-attendance, cancellation and unplanned overnight admission should be assessed.

FURTHER READING

British Association of Day Surgery, www.bads.co.uk

Chung, F., Mezei, G., Tong, D. Pre-existing medical conditions as predictors of adverse events in day-case surgery. Br. J. Anaesth. 1999;83:262–270.

Davies, K.E., Houghton, K., Montgomery, J.E. Obesity and day case surgery. Anaesthesia. 2001;56:1090–1115.

Duncan, P.G., Cohen, M.M., Tweed, W.A., et al. The Canadian four centre study of anaesthetic outcomes: III Are anaesthetic complications predictable in day surgical practice? Can. J. Anaesth. 1992;39:440–448.

Ilfeld, B.M., Morey, T.E., Wright, T.W. Continuous interscalene brachial plexus block for postoperative pain control at home: a randomized, double-blinded, placebo controlled study. Anesth. Analg. 2003;96:1089–1095.

Millar, J.M., Rudkin, G.E., Hitchcock, M. Practical anaesthesia and analgesia for day surgery. Oxford: BIOS Scientific Publishers; 1997.

Modernisation Agency Day Surgery Programme, www.wise.nhs.uk

The Association of Anaesthetists of Great Britain & Ireland. Perioperative management of the morbidly obese patient, 2007. http://www.aagbi.org/sites/default/files/Obesity07.pdf

Urmey, W.F. Spinal anaesthesia for outpatient surgery. Best Pract. Res. Clin. Anesthesiol. 2003;17:335–346.

White, P.F., Issioui, T., Skrivanek, G.D. The use of continuous popliteal sciatic nerve block after surgery involving the foot and ankle: does it improve the quality of recovery? Anesth. Analg. 2003;97:1303–1309.

Williams, B.A., Kentor, M.L., Vogt, M.T. Femoral-sciatic nerve blocks for complex outpatient knee surgery are associated with less postoperative pain before same day discharge: a review of 1200 consecutive cases from the period 1996–1999. Anesthesiology. 2003;98:1206–1213.