Cysts and Lipomas

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12 Cysts and Lipomas

Removing “lumps and bumps” is common in an outpatient setting. The clinician often encounters a multitude of benign cystic lesions and lipomas on physical exam. The most common reasons to remove them include pain and discomfort, growth, discharge, infection or inflammation, and cosmetic concerns. These lesions present as masses and it can sometimes be hard to differentiate them from solid tumors or lymph nodes. Subsequently they may also need to be removed to verify a diagnosis. Epidermal inclusion cysts will frequently have a central punctum (pore) over them and be smooth. There is often a history of foul-smelling drainage. Lipomas are generally softer and more irregular. This chapter discusses treatment options for epidermal inclusion cysts, lipomas, and digital mucinous cysts. These comprise a large portion of the lumps and bumps encountered. An understanding of the basic approaches to each lesion should make treating them more efficient and effective.

Epidermal Inclusion Cysts and Variants

Epidermal inclusion cysts arise from a plugged follicular opening, resulting in a nodular cyst filled with cheesy malodorous keratin material. These are also commonly and incorrectly called sebaceous cysts but do not in fact contain any sebum. Unfortunately, the ICD code for these cysts is named “sebaceous cyst” so you must know this misnomer for billing purposes. Other names include infundibular cysts, keratinous cysts, and epidermoid cysts. Generally, these present as a compressible but nonfluctuant nodule, which can be diagnosed clinically due to a comedo-like central punctum that can be distinguished at the apex (Figure 12-1). Because the keratin material inside the cyst wall is highly inflammatory, any cyst that has ruptured can spark a vigorous inflammatory response that can be mistaken for cellulitis (Figure 12-2). Even if these do become superinfected, the treatment of choice is incision and drainage to remove the inflammatory and/or infected contents.

Pilar cysts (also known as trichilemmal cysts and commonly called wens) are very similar to epidermal inclusion cysts with the exception that the capsule is much thicker and the location generally on the scalp (Figures 12-3 and 12-4). Pilar cysts rarely have a punctum but the thickness of the capsule makes removal somewhat easier. These can also become very large but in most cases they are 5 to 20 mm in size. It is not unusual for the hair to become thinned or actually stop growing over the cyst (Figures 12-3 and 12-4).

One variant of the epidermal cyst is the milium cyst. Milia are histologically identical to classic epidermal cysts but only grow to 1 to 2 mm. They are generally located around the eyes and central portion of the face (See Figure 33-20 in Chapter 33, Procedures to Treat Benign Conditions).

Cysts can be located almost anywhere but are common on the trunk, neck, face, and behind the ears. They range in size from millimeters to centimeters. Epidermal inclusion cysts are benign; however, there are rare proliferating epidermal inclusion cysts that can become carcinogenic. Any cyst that does not look 100% typical on excision should be sent to the pathologist. A full differential diagnosis is given in Box 12-1.

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FIGURE 12-5 A Bartholin’s duct cyst.

(Copyright Richard P. Usatine, MD.)

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FIGURE 12-7 A solid cystic hidradenoma.

(Copyright Richard P. Usatine, MD.)

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FIGURE 12-9 A mucinous cystadenoma near the eye.

(Copyright Richard P. Usatine, MD.)

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FIGURE 12-11 Pilonidal cyst.

(Copyright Richard P. Usatine, MD.)

Dermoid cysts are far less common. They occur along congenital lines of cleavage (lingually, lateral eyes, behind the ears, and base of the nose) due to sequestration of embryonic cells. Unlike the common cyst, they are usually found in children and teenagers. So, young age is a warning sign for “something different.” Facial cysts in young children need to be approached with caution and may need an imaging study before performing an excision.

The occurrence of multiple true sebaceous cysts at a younger age is termed steatocystoma multiplex, which is a genetically inherited problem. These capsules are extremely thin. Small fluid-filled very thin-walled cysts around the eyes are called hidrocystomas (Figure 12-10).

Several techniques for removing epidermal inclusion cysts and pilar cysts are described below. The best approach depends on size, location, and cyst condition. The minimal excision technique is simplest. Other methods include elliptical excision and incision and drainage with iodine crystals. Each offers advantages in select cases. Familiarity with various techniques balances preventing recurrence with maximizing efficiency and cosmetic outcome.

Contraindications for Cyst Removal

Avoid trying to remove cysts that are actively inflamed (Figure 12-2). Although it can be done successfully, wound healing may be impaired. The keratinaceous material in epidermal inclusion cysts is highly immunogenic and an inflamed cyst should be treated with incision and drainage and allowed to heal before attempting to remove the cyst wall. Antibiotics are rarely helpful. Small lesions can be excised going around the entire area of inflammation.1
Diagnosis is usually made on clinical grounds before proceeding with removal. Keep the differential in mind even though the diagnosis may seem certain (Box 12-1). For example, a dermoid cyst on the face can communicate with the cerebrospinal fluid in some circumstances. Consider imaging for a possible dermoid cyst if the cyst has been present on the face since early childhood and is midline (Figure 12-13). When encountering something atypical, send samples to pathology, or confer with a colleague before proceeding.

Minimal Excision Technique

The minimal incision technique for removing cysts involves purposefully incising the cyst wall and expressing its contents allowing cyst removal through a smaller incision (linear opening or small punch rather than a larger ellipse that surrounds the cyst).

Minimal Excision Technique: Steps and Principles

Preoperative Measures

Prep the area with an antiseptic such as chlorhexidine or alcohol. Mark the apex with a line (Figure 12-14), a small ellipse, or a small circle to orient a punch depending on which technique is chosen to enter the cyst wall. It is also worthwhile to draw a circle around the widest margins of the cyst (Figure 12-14). You may use a fenestrated drape if you plan to place a suture.
Inject anesthetic around the cyst with a 27- to 30-gauge needle. Avoid injecting anesthesia directly into the cyst because it may squirt cyst contents out of the punctum, producing an unpleasant smell (Figure 12-14). If the anesthesia enters the cyst and does not squirt out it may cause increased pain for the patient as the pressure builds inside the cyst. It is best to plan to inject around the cyst performing a ring block. In Figure 12-14 the arrows show how you can start at one corner of a square and inject at the arrow ahead each time so that the new injection will be less painful from the effect of the preceding injection. A fifth injection may be added to the skin above the cyst at the site for the planned incision to ensure a painless surgery (Figure 12-15). In Figure 12-16 the pressure of the anesthesia has caused some keratin to be extruded from the punctum without any harm.

Performing the Procedure

Stretch the skin to anchor the lesion. Incise a linear or punch opening (Figure 12-17A and B) over the cyst apex and into the cyst itself. Alternatively, cut a small ellipse instead of a linear or circular opening.
Express all cyst contents with firm digital pressure on the cyst and surrounding tissue (Figure 12-17C). Keep plenty of 4 × 4 gauze on the field to mop up the contents of the cyst.
Inspect the material removed. You should have extracted a nearly complete cyst wall (Figures 12-19 and 12-20). Pilar cysts have a thicker wall and are easier to extract intact than an epidermal cyst (Figure 12-21). You may be able to piece sections together like a jigsaw puzzle to make sure that the entire cyst is out.

Alternatives to the Minimal Excision Technique

A couple of alternatives to the minimal excision technique are worth discussing.

Elliptical Excision

Full elliptical excisions are covered in Chapter 11. This technique may be a good option if cysts have been heavily manipulated or have recurred. One approach is to avoid cutting into the cyst wall and attempting to remove the cyst whole. Another approach is similar to the minimal cyst removal in which the cyst is cut on purpose and the contents are evacuated to allow the cyst to be removed through a smaller ellipse. If the cyst is large and elevated, make sure the width of the ellipse is equal to the width of the cyst to avoid dog ears (standing cones).3 This is especially true with large protuberant pilar cysts (Figure 12-22). The scalp will not lay flat unless the ellipse is as long as the cyst. The elliptical excision method is preferred with any large protuberant cysts that would leave redundant skin if the cyst is excised through a punch or a linear incision.

Incision and Drainage of Inflamed and Infected Cysts

When patients present with an acutely inflamed or possibly infected cyst, the treatment is to incise, drain, and pack the wound. The same principles apply as those described in Chapter 17, Incision and Drainage. Use a ring block for anesthesia and a No. 11 blade scalpel to incise the inflamed area. Because the incision will be packed and not closed, clean technique is adequate. Antibiotics are rarely beneficial because the majority of these inflammatory changes are due to a reaction to the ruptured contents rather than a true infection. Antibiotics are not needed especially after an I&D, nor are cultures. Some clinicians may want to culture and use antibiotics in immune-suppressed patients, but even then the definitive treatment is I&D.

Hidrocystomas

Hidrocystomas (Figure 12-10) can be easily excised using pickups and cutting a small thin ellipse over the cyst with a sharp tissue scissor. The fluid will drain out easily. There should be little bleeding so pressure alone should be adequate for hemostasis.

Dermoid Cysts

Be aware of the precautions cited earlier. If a dermoid cyst (Figure 12-13) is suspected, excisional removal is indicated. If a dermoid cyst is found on the face of a young child, refer for removal under sedation or general anesthesia.

Lipomas

Lipomas are subcutaneous benign tumors composed of adipose tissue held together with connective tissue. Although they may be encapsulated, in general they are more amorphous, lobulated masses that are either slightly lighter or darker than surrounding adipose. Often it is nearly indistinguishable from normal tissue by color, but the fat may be held together so that it is separate from the surrounding subcutaneous fat. Lesions typically arise after the fourth decade of life and present as single or multilobed soft tumors that are easily compressible and have a doughy consistency. Lipomas most commonly arise over the neck and trunk, though they can also be found on the extremities and face. Usually patients complain of lipomas when they are located on pressure-bearing areas and become painful, when they arise in cosmetically sensitive areas, or when they become very large. In these cases, and in instances of rapid growth, it is reasonable to remove them. Another indication would be if the diagnosis is in doubt.

Lipomas can usually be diagnosed clinically, although the differential diagnosis includes many of the same entities discussed for cysts (Box 12-1). Additional considerations are hematoma, panniculitis, rheumatic nodules, and metastatic cancer. Rapidly growing subcutaneous masses should be removed and sent for pathology. Several approaches are used to remove lipomas: incision and expression, elliptical excision, and liposuction.

Preoperative

After obtaining informed consent, prep the area with chlorhexidine. Mark the borders of the lipoma with a surgical marking pen (Figure 12-23A). Locate the best area for the linear incision or punch biopsy and mark it with the marking pen taking into account skin lines and cosmetic considerations (Figure 12-23A). The incision need not be directly in the center of the lesion.

Incision and Pressure Method

The easiest method to remove lipomas is the incision and pressure method. Draw out the linear incision so that it is approximately one-third to one-half the diameter of the lipoma (Figure 12-24A). Make a linear incision through the skin over the top of the lipoma. Hold the No. 11 blade perpendicular to the skin and cut through the skin into the lipoma with a sawing motion. Fortunately, lipomas are relatively avascular so little bleeding should be encountered. If there is much bleeding, reassess the diagnosis and procedure immediately.

Once the incision has been made, insert and spread the curved hemostats around the edge of the lipoma to break up the fibrous bands that attach it to the surrounding tissue. Do this through 360 degrees and try to get under the lipoma as well. Then express the lipoma through the incision using digital pressure (Figure 12-24B). If this does not work, use the hemostat again to free the lipoma further. If this still does not work, consider extending the incision on both sides to give more room for the lipoma to come out. Pulling the lipoma with the hemostat clamped on it can help while an assistant is squeezing the lipoma out from below with digital pressure.

Once the lipoma is out, see if it appears whole and explore the cavity to make sure the entire lipoma has been removed. Bleeding should be nonexistent to minimal. Hold pressure on the defect to express any blood or fluid. The incision can be closed with simple interrupted sutures or subcuticular sutures. If the defect is large consider placing some deep sutures to close dead space (see Chapter 6, Suturing Techniques). Some clinicians use Steri-Strips with no sutures underneath a pressure dressing. With experience and efficient office staff, this procedure can be done in 10 minutes. Even a large lipoma can be removed using this method (Figure 12-25).

Examination and Pathology

Inspect the lipoma and feel it between your fingers. It should be a contiguous yellow mass without significant vascularity or calcifications (Figure 12-25E). Any hint of abnormality or odd behavior of the tissue during the procedure should prompt you to send the specimen for pathology. Any lesions with significant vascularity, size, calcifications, or other worrisome features should be sent to pathology to confirm a benign diagnosis.

Elliptical Excision of A Lipoma

A true elliptical excision for removal can be practical for larger lipomas or those under thick skin (back of the neck, posterior trunk) and with lesions that are of uncertain diagnosis or unusually firm. The elliptical excision is covered fully in Chapter 11. It may be more helpful to leave the elliptical piece of skin attached to the dermis and use the skin as a convenient handle to manipulate the lipoma with a hemostat, clamp, or forceps. The scar will be larger using this technique, but in some instances that is not a concern.

Digital Mucous (Myxoid) Cysts

Digital mucous cysts or myxoid cysts are similar to ganglia but arise on the distal fingers and occasionally toes (Figures 12-27 and 12-28). These are the most common cysts on the hand and are benign. The exact etiology is uncertain, but the cysts likely form from the mucoid degeneration associated with arthritis. Cysts usually present after the fifth decade of life, but can present earlier when associated with arthropathy such as rheumatoid arthritis. The most common location is the distal interphalangeal joint, on the dorsal aspect. Lesions that occur in the proximal nail fold can distort the lunula, put pressure on the matrix, and cause nail deformities and pain (Figure 12-28).

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FIGURE 12-27 Digital mucous cyst on a toe.

(Copyright Richard P. Usatine, MD.)

When treatment is sought, options range from observation to joint surgery with osteophyte removal and flap reconstruction. In the office setting, the most common options are draining with repeat sterile needling and cryotherapy.1,2 Alternatives include the injection of sclerosing agents, steroid injections, or excision with flap repair. All options risk recurrence with radical joint surgery as the most definitive and most costly option.

Alternatives to Cryotherapy

Minami et al.7 described a method of cryotherapy that involved direct contact with a probe or liquid nitrogen–soaked cotton tipped swab applied over a thin plastic film after the pseudocyst had been drained. Presumably this prevented cotton contents from adhering to the tissue. After a median of 2.64 treatments, they had an 85% to 92% cure rate.

Another very good alternative is serial needling. This can be done in the office or at home by a capable patient who is given sterile needles. The success rate is 70% with minimal expense aside from office visits.8 Another option is excision of the cyst in the office with a small rotation flap pinned with two small sutures. This requires a digital block and a surgical tray, but the long-term cure rate may rival joint surgery.9 A similar but simpler technique was described wherein a three-sided or fingertip-shaped pedicle is created around the cyst and undermined—creating a small flap. Then, instead of rotating or transposing the cyst containing flap, tack it back down with one or two sutures. The scarring that forms theoretically blocks a path from the joint space to the cyst.10

Coding and Billing Pearls

Epidermal cysts (ICD-9 code 706.2) are skin lesions and as such, excisions are coded by the size of the cyst, the location, and the fact that they are benign. Simple excision and repair includes the anesthetic, the excision, the repair, and suture removal. The size is based on the size of the cyst, not the size of the incision so a minimal cyst removal is not compensated at a lower rate because the incision was shorter. Additional charges are made for an intermediate closure if deep sutures are needed to close dead space or approximate wound edges under tension. The intermediate closure charge is based on the size of the final closed wound. Make sure to document the reason for the intermediate closure to avoid a denial of the service.

If the cyst was infected or inflamed and the procedure performed was only an incision and drainage, use the code for simple I&D (10060). Use this code if the lesion was opened and drained but not packed or sutured. If multiple cysts were done, if it was complicated with the use of packing or iodine crystals, or if the sack was removed, then the correct code is 10061 for “multiple or complex removal.” Note that just adding packing to the opened incision and drainage automatically qualifies the procedure as a complex I&D (10061).

Lipoma excisions may be coded as for a skin lesion or a subcutaneous tumor. If the lipoma is superficial in the subcutaneous fat below the skin, the removal may be coded the same as for an excision of an epidermal cyst (excision of a benign skin lesion). Similar to epidermal cysts, the size is based on the measurement of the lipoma and not the incision. Also, if a two-layered closure is performed, document the necessity for this and bill for an intermediate closure.

Lipomas may also be coded with the new 2010 CPT codes for excision of a subcutaneous tumor based on anatomic location. Some coders advocate using these codes only for deep lipomas including those under fascia or under muscle. Other coders state that all lipomas should be coded with these codes. See Table 38-13 in Chapter 38, Surviving Financially, for the specific soft tissue tumor codes based on location of the lipoma. The most commonly needed codes for lipomas are listed in Table 12-1. These soft tissue tumor codes are all inclusive. Neither the length of the incision nor the type of repair that is used matter. The large lipoma in Figure 12-25 was deep based on the visibility of the latissimus dorsi muscle at the time of excision and could easily be coded as 21931. If a decision is made to code it as a skin lesion (an acceptable alternative), then the code used would be 11446 for a benign skin lesion excised with a diameter over 4.0 cm. Both coding methods pay well and are considered legitimate for the procedure performed. The specific ICD-9 codes for lipomas are 214.0 for the face and 214.1 for other areas.

TABLE 12-1 Subcutaneous Soft Tissue Tumor Excisions (Including Lipomas)

CPT

Description

2010 National Medicare Reimbursement

21930 Back or flank, <3 cm 430
21931 Back or flank, ≥3 cm 459
24071 Upper arm or elbow, <3 cm 395
24075 Upper arm or elbow, ≥3 cm 441
25071 Forearm and/or wrist, <3 cm 341
25075 Forearm and/or wrist, ≥3 cm 414
21011 Face or scalp, <2 cm 306
21012 Face or scalp, ≥2 cm 328

As of 2010, four new codes (21011, 21012, 21013, and 21014) are available for reporting the excisions of soft tissue tumors (including lipomas) of the face and scalp. If a lipoma is less than 2 cm in maximum dimension, report code 21011. If the lipoma is larger than 2 cm, report 21012. If the tumor is subfascial (i.e., intramuscular or subgaleal) and is less than 2 cm in maximum dimension, report code 21013. If it is larger than 2 cm, report 21014. Therefore, the excision of a 3-cm submuscular lipoma of the forehead is reported with code 21014.

Speak with staff and/or consultants who support coding and billing functions to help make decisions when the best coding strategy for a specific lipoma is not clear.

(For further tips see Chapter 38, Surviving Financially.)