112 Constipation
Clinical Presentation
Differential Diagnosis
Although the majority of children with constipation have functional disease, it is important to consider the broad differential diagnosis of constipation in the pediatric population (Box 112-1). Patients with an organic disease usually present with a range of symptoms or physical findings in addition to constipation. Children with Hirschsprung’s disease (Figure 112-1) often do not pass meconium during the first 36 hours of life and have problems with constipation beginning in infancy (Table 112-1). On examination, the rectum is generally very small and empty of stool. Patients with constipation secondary to hypothyroidism generally have other symptoms and findings, including lethargy, hypotonia, a large fontanelle if presenting in infancy, short stature, cold intolerance, dry skin, feeding problems, and a palpable goiter (see Chapter 68). Celiac disease can also present with constipation in addition to poor growth and abdominal pain. Children with lead poisoning can present with constipation in addition to vomiting and intermittent abdominal pain. Patients with a tethered spinal cord