Cerebrospinal and other body fluids

Published on 02/03/2015 by admin

Filed under Basic Science

Last modified 02/03/2015

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Cerebrospinal and other body fluids

Cerebrospinal fluid

Cerebrospinal fluid (CSF) is produced by the choroid plexuses, partly by ultrafiltration and partly by secretion, and fills and circulates through the ventricles and spinal cord. Compared with plasma, it has less protein, and the concentrations of protein-bound components like bilirubin are similarly reduced. Its electrolyte composition is similar to but distinct from plasma (more chloride, less potassium and calcium). Infection or the presence of blood in the CSF alters its composition. This provides the basis for biochemical analysis of CSF in the diagnosis of subarachnoid haemorrhage (SAH) and meningitis.