Echogenic foci or “bright spots” of the ovary

In a study by Brown and colleagues, small ovarian calcifications (1 to 3 mm) were found in more than half of women examined with transvaginal ultrasound who were scheduled to undergo oophorectomy for unrelated diagnoses. The mean number of echogenic foci per ovary was 8.7 (range, 1 to 30). In 23 ovaries with sonographically detected echogenic foci, the location was peripheral in 17 ovaries, central in 1, and both central and peripheral in 5. Histology identified a potential cause of the echogenic foci in 17 of the 23 ovaries (74%). The most frequent sole histologic finding was a corpus albicans with hemosiderin (26% of cases). Inclusion cysts were also frequently seen along with a corpus albicans. The foci were not associated with either endometriosis or malignancy.